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Dora M Kovacs

Massachusetts General Hospital

$12,707,695
Attributed
$20,036,251
Total exposure
9
Grants
5
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $4.7M · FY200518
$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18

Funding mix

By agency

NIH$32,600,641 · 10

By mechanism

P01$25,751,503 · 8
R01$6,849,138 · 2

Top collaborators

Most similar at Massachusetts General Hospital

Same institution · by research overlap

Others in their field

Top investigators on “Alzheimer&Apos

Research focus

Alzheimer&AposBaseNeuronsCellsS DiseaseBrainProteinsAffectMediatingIn VivoMembranePresenilinBiologyEventSecretaseGenerationsComplexInhibitor/AntagonistProgramsIn VitroProductionMutationBinding (Molecular Function)Amyloid Precursor Protein Processing

Grant awards (58)

Presenilin Biology and the Mechanisms of Alzheimer's Disease$2,095,236
P01 · FY2018 · AG
Presenilin Biology and the Mechanisms of Alzheimer's Disease$2,096,690
P01 · FY2017 · AG
STRUCTURE, FUNCTION AND REGULATION OF GAMMA-SECRETASE$699,153
P01 · FY2017 · AG
ROLE OF PRESENILIN 1 AT THE SYNAPSE$426,525
P01 · FY2017 · AG
ROLE OF SYNAPTOTAGMINS IN APP PROCESSING$418,739
P01 · FY2017 · AG · contact PI
EFFECTS OF APP-SELECTIVE GSMS AND ADAMIO MUTATIONS ON Y-SECRETASE ACTIVITY$406,723
P01 · FY2017 · AG
ADMINISTRATIVE AND EDUCATIONAL CORE$145,550
P01 · FY2017 · AG
Presenilin Biology and the Mechanisms of Alzheimer's Disease$2,096,690
P01 · FY2016 · AG
STRUCTURE, FUNCTION AND REGULATION OF GAMMA-SECRETASE$699,153
P01 · FY2016 · AG
ROLE OF PRESENILIN 1 AT THE SYNAPSE$426,525
P01 · FY2016 · AG
ROLE OF SYNAPTOTAGMINS IN APP PROCESSING$418,739
P01 · FY2016 · AG · contact PI
EFFECTS OF APP-SELECTIVE GSMS AND ADAMIO MUTATIONS ON Y-SECRETASE ACTIVITY$406,723
P01 · FY2016 · AG
ADMINISTRATIVE AND EDUCATIONAL CORE$145,550
P01 · FY2016 · AG
Presenilin Biology and the Mechanisms of Alzheimer's Disease$2,033,235
P01 · FY2015 · AG
STRUCTURE, FUNCTION AND REGULATION OF GAMMA-SECRETASE$677,724
P01 · FY2015 · AG
ROLE OF PRESENILIN 1 AT THE SYNAPSE$413,729
P01 · FY2015 · AG
ROLE OF SYNAPTOTAGMINS IN APP PROCESSING$406,175
P01 · FY2015 · AG · contact PI
EFFECTS OF APP-SELECTIVE GSMS AND ADAMIO MUTATIONS ON Y-SECRETASE ACTIVITY$394,522
P01 · FY2015 · AG
ADMINISTRATIVE AND EDUCATIONAL CORE$141,085
P01 · FY2015 · AG
Presenilin Biology and the Mechanisms of Alzheimer's Disease$2,093,246
P01 · FY2014 · AG
STRUCTURE, FUNCTION AND REGULATION OF GAMMA-SECRETASE$696,221
P01 · FY2014 · AG
ROLE OF PRESENILIN 1 AT THE SYNAPSE$426,525
P01 · FY2014 · AG
ROLE OF SYNAPTOTAGMINS IN APP PROCESSING$418,739
P01 · FY2014 · AG · contact PI
EFFECTS OF APP-SELECTIVE GSMS AND ADAMIO MUTATIONS ON Y-SECRETASE ACTIVITY$406,723
P01 · FY2014 · AG
ADMINISTRATIVE AND EDUCATIONAL CORE$145,038
P01 · FY2014 · AG
Presenilin Biology and the Mechanisms of Alzheimer's Disease$2,149,293
P01 · FY2013 · AG
STRUCTURE, FUNCTION AND REGULATION OF GAMMA-SECRETASE$695,267
P01 · FY2013 · AG
ROLE OF PRESENILIN 1 AT THE SYNAPSE$445,639
P01 · FY2013 · AG
ROLE OF SYNAPTOTAGMINS IN APP PROCESSING$437,853
P01 · FY2013 · AG · contact PI
EFFECTS OF APP-SELECTIVE GSMS AND ADAMIO MUTATIONS ON Y-SECRETASE ACTIVITY$425,837
P01 · FY2013 · AG
ACAT inhibitors regulate palmitoylated APP and Abeta production$356,056
R01 · FY2013 · NS · contact PI
ADMINISTRATIVE AND EDUCATIONAL CORE$144,697
P01 · FY2013 · AG
ACAT inhibitors regulate palmitoylated APP and Abeta production$369,647
R01 · FY2012 · NS · contact PI
PS1 and BACE1 regulate processing and activity of voltage-gated sodium channels$310,755
R01 · FY2012 · AG · contact PI
Common regulation of BACE1 and y-secretase substrate processing$171,620
P01 · FY2012 · AG · contact PI
Common regulation of BACE1 and y-secretase substrate processing$469,879
P01 · FY2011 · AG · contact PI
ACAT inhibition regulates ERAD of APP and Abeta production$337,642
R01 · FY2011 · NS · contact PI
PS1 and BACE1 regulate processing and activity of voltage-gated sodium channels$310,755
R01 · FY2011 · AG · contact PI
Common regulation of BACE1 and y-secretase substrate processing$463,077
P01 · FY2010 · AG · contact PI
ACAT inhibition regulates ERAD of APP and Abeta production$341,086
R01 · FY2010 · NS · contact PI
PS1 and BACE1 regulate processing and activity of voltage-gated sodium channels$323,299
R01 · FY2010 · AG · contact PI
Common regulation of BACE1 and y-secretase substrate processing$373,561
P01 · FY2009 · AG · contact PI
ACAT inhibition regulates ERAD of APP and Abeta production$344,531
R01 · FY2009 · NS · contact PI
PS1 and BACE1 regulate processing and activity of voltage-gated sodium channels$325,489
R01 · FY2009 · AG · contact PI
Common regulation of BACE1 and y-secretase substrate processing$360,631
P01 · FY2008 · AG · contact PI
ACAT inhibition regulates ERAD of APP and Abeta production$344,531
R01 · FY2008 · NS · contact PI
PS1 and BACE1 regulate processing and activity of voltage-gated sodium channels$323,644
R01 · FY2008 · AG · contact PI
GAMMA SECRETASE ACTIVITY N COORDINATED CELL-CELL INTERACTIONS$472,748
P01 · FY2007 · AG · contact PI
Role of the g-secretase/PS1 complex in APP processing$383,008
R01 · FY2007 · AG · contact PI
ACAT inhibition regulates ERAD of APP and Abeta production$344,531
R01 · FY2007 · NS · contact PI
GAMMA SECRETASE ACTIVITY IN CELL CELL INTERACTIONS$406,443
P01 · FY2006 · AG · contact PI
Role of the g-secretase/PS1 complex in APP processing$394,448
R01 · FY2006 · AG · contact PI
Cholesterol distribution & regulation of AB generation$320,976
R01 · FY2006 · NS · contact PI
Role of the g-secretase/PS1 complex in APP processing$403,940
R01 · FY2005 · AG
Cholesterol distribution &regulation of AB generation$328,700
R01 · FY2005 · NS
Cholesterol distribution &regulation of AB generation$328,700
R01 · FY2004 · NS
Cholesterol distribution &regulation of AB generation$328,700
R01 · FY2003 · NS
Cholesterol distribution &regulation of AB generation$328,700
R01 · FY2002 · NS