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Tracy L Young-Pearse

Brigham And Women'S Hospital

$25,012,544
Attributed
$28,202,720
Total exposure
20
Grants
17
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $10.8M · FY200625
$20M$15M$10M$5M$0
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$31,911,434 · 21

By mechanism

RF1$11,647,240 · 5
R01$9,059,752 · 4
U54$6,462,190 · 3
R21$1,929,030 · 4
R33$1,282,313 · 1
R00$717,487 · 1

Top collaborators

Most similar at Brigham And Women'S Hospital

Same institution · by research overlap

Others in their field

Top investigators on “Alzheimer&Apos

Research focus

Alzheimer&AposNeuronsGenesMolecularCellsS DiseaseGeneticBrainInduced Pluripotent Stem CellMutationPathway InteractionsPlayPhenotypeLinkAffectPathogenesisBrain TissueCell LineAutopsyAstrocytesMediatingPathologyFunctional DisorderLead

Grant awards (46)

Development of Human Microphysiological Systems for Testing of AD/ADRD Interventional Strategies across Genetically Diverse Populations$3,708,714
U54 · FY2025 · AG · contact PI
Establishment of a Human Microphysiological System to Elucidate Cellular Mechanisms Underlying Vulnerability to AD$2,683,965
RF1 · FY2025 · NS · contact PI
MPS Models Development and Validation Core$1,873,030
U54 · FY2025 · AG · contact PI
Administrative and Data Management Core$880,446
U54 · FY2025 · AG · contact PI
Probing Heterogeneity of Alzheimer's Disease Using iPSCs$809,963
R01 · FY2025 · AG · contact PI
Identifying cell type-specific autonomous and non-autonomous interactions in AD$802,494
R01 · FY2025 · AG
Cell and Molecular Consequences of Alzheimer's Disease Genetic Variants on BBB Integrity and Function$908,817
R01 · FY2024 · NS · contact PI
Probing Heterogeneity of Alzheimer's Disease Using iPSCs$835,443
R01 · FY2024 · AG · contact PI
Probing Heterogeneity of Alzheimer's Disease Using iPSCs$855,193
R01 · FY2023 · AG · contact PI
Identifying cell type-specific autonomous and non-autonomous interactions in AD$2,567,371
RF1 · FY2022 · AG
Probing Heterogeneity of Alzheimer's disease using iPSCs$489,251
R01 · FY2022 · AG · contact PI
Probing Heterogeneity of Alzheimer's disease using iPSCs$489,200
R01 · FY2021 · AG · contact PI
Cell and Molecular Consequences of Alzheimer's Disease Genetic Variants on BBB Integrity and Function$3,598,522
RF1 · FY2020 · NS · contact PI
Probing Heterogeneity of Alzheimer's disease using iPSCs$524,557
R01 · FY2020 · AG · contact PI
Establishing a human cellular model of sex differences in the brain$223,750
R21 · FY2020 · MH · contact PI
Probing Heterogeneity of Alzheimer's disease using iPSCs$461,347
R01 · FY2019 · AG · contact PI
Building Novel Predictive Networks for high-throughput, in-silico Key Driver Prioritization to Enhance Drug Target Discovery in AMP-AD and M2OVE-AD$383,750
RF1 · FY2019 · AG
Establishing a human cellular model of sex differences in the brain$268,500
R21 · FY2019 · MH · contact PI
Genes and developmental signaling pathways in neuropsychiatric disorders$527,883
R01 · FY2018 · MH · contact PI
Probing Heterogeneity of Alzheimer's disease using iPSCs$416,553
R01 · FY2018 · AG · contact PI
Feasibility of studying vulnerability versus protection to high amyloid load using iPSCs$266,250
R21 · FY2018 · AG · contact PI
Building Novel Predictive Networks for high-throughput, in-silico Key Driver Prioritization to Enhance Drug Target Discovery in AMP-AD and M2OVE-AD$1,710,225
RF1 · FY2017 · AG
Genes and developmental signaling pathways in neuropsychiatric disorders$528,960
R01 · FY2017 · MH · contact PI
Altered APP metabolism triggers changes in tau that cause dementia$266,250
R21 · FY2017 · AG · contact PI
Feasibility of studying vulnerability versus protection to high amyloid load using iPSCs$221,875
R21 · FY2017 · AG · contact PI
Building Novel Predictive Networks for high-throughput, in-silico Key Driver Prioritization to Enhance Drug Target Discovery in AMP-AD and M2OVE-AD$218,521
RF1 · FY2017 · AG
Genes and developmental signaling pathways in neuropsychiatric disorders$441,270
R01 · FY2016 · MH · contact PI
Detection of cell type specific effects of pathway manipulation in neural cells$416,390
R33 · FY2016 · AG · contact PI
Altered APP metabolism triggers changes in tau that cause dementia$221,875
R21 · FY2016 · AG · contact PI
Genes and developmental signaling pathways in neuropsychiatric disorders$88,748
R01 · FY2016 · MH · contact PI
Genes and developmental signaling pathways in neuropsychiatric disorders$440,551
R01 · FY2015 · MH · contact PI
Detection of cell type specific effects of pathway manipulation in neural cells$414,766
R33 · FY2015 · AG · contact PI
Detection of cell type specific effects of pathway manipulation in neural cells$451,157
R33 · FY2014 · AG · contact PI
Genes and developmental signaling pathways in neuropsychiatric disorders$439,522
R01 · FY2014 · MH · contact PI
Functions of DISC1 and APP in Cortical Development and Neuropsychiatric Disorders$226,418
R00 · FY2013 · MH · contact PI
Profiling of cortical cells by microengraving and mass spectrometry imaging$192,780
R21 · FY2013 · MH · contact PI
Analyses of AD relevant phenotypes in neural cells derived from human iPSCs$484,886
RF1 · FY2012 · AG · contact PI
Confocal Microscope for the Study of Neurologic Diseases$482,783
S10 · FY2012 · OD · contact PI
Profiling of cortical cells by microengraving and mass spectrometry imaging$267,750
R21 · FY2012 · MH · contact PI
Functions of DISC1 and APP in Cortical Development and Neuropsychiatric Disorders$242,069
R00 · FY2012 · MH · contact PI
Functions of DISC1 and APP in Cortical Development and Neuropsychiatric Disorders$249,000
R00 · FY2011 · MH · contact PI
Functions of DISC1 and APP in Cortical Development and Neuropsychiatric Disorders$89,367
K99 · FY2010 · MH · contact PI
Functions of DISC1 and APP in Cortical Development and Neuropsychiatric Disorders$90,000
K99 · FY2009 · MH · contact PI
Functions of APP Family Members in Neuronal Development$52,048
F32 · FY2008 · NS · contact PI
Functions of APP Family Members in Neuronal Development$50,428
F32 · FY2007 · NS · contact PI
Functions of APP Family Members in Neuronal Development$48,796
F32 · FY2006 · NS · contact PI