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Oleg Butovsky

Brigham And Women'S Hospital

$13,581,013
Attributed
$20,386,873
Total exposure
11
Grants
6
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $2.6M · FY201425
$5M$3.8M$2.5M$1.3M$0
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$20,386,873 · 11

By mechanism

R01$17,842,338 · 6
R21$1,476,541 · 3
R41$1,067,994 · 2

Top collaborators

Most similar at Brigham And Women'S Hospital

Same institution · by research overlap

Others in their field

Top investigators on “Alzheimer&Apos

Research focus

Alzheimer&AposMicrogliaPhenotypeCellsBrainDisease ProgressionInflammatoryMediatingPathway InteractionsMouse ModelAffectBaseMonocyteTransforming Growth Factor BetaNerve DegenerationImmuneAblationSignal TransductionRegulationMacrophageInvestigationMolecular ProfilingMolecularFunctional Disorder

Grant awards (41)

Role of a novel risk loci HAVCR2 of late-onset Alzheimer's disease in the regulation of microglial response in neurodegeneration$813,314
R01 · FY2025 · AG
Gender-dependent APOE4 regulation of neutrophil-microglia crosstalk in Alzheimer's disease$723,316
R01 · FY2025 · AG · contact PI
Targeting TGFb/IFNy-IRF8 Signaling to Modulate Monocytes and their Crosstalk with Microglia and Astrocytes to Treat Multiple Sclerosis$644,207
R01 · FY2025 · NS · contact PI
Targeting aVb8 integrin to restore astrocyte-microglia crosstalk to treat Alzheimer's disease$254,896
R41 · FY2025 · AG
Role of a novel risk loci HAVCR2 of late-onset Alzheimer's disease in the regulation of microglial response in neurodegeneration$829,912
R01 · FY2024 · AG
Gender-dependent APOE4 regulation of neutrophil-microglia crosstalk in Alzheimer's disease$738,078
R01 · FY2024 · AG · contact PI
Role of a novel risk loci HAVCR2 of late-onset Alzheimer's disease in the regulation of microglial response in neurodegeneration$831,274
R01 · FY2023 · AG
Gender-dependent APOE4 regulation of neutrophil-microglia crosstalk in Alzheimer's disease$694,787
R01 · FY2023 · AG · contact PI
Restoration of Homeostatic Microglia in CNS Inflammation$392,305
R01 · FY2023 · NS · contact PI
Gender-dependent APOE4 regulation of neutrophil-microglia crosstalk in Alzheimer's disease$694,787
R01 · FY2022 · AG · contact PI
APOE e4 negative regulation of microglia-astrocytes crosstalk in Alzheimer's disease$429,168
R21 · FY2022 · AG · contact PI
Restoration of homeostatic microglia in CNS inflammation$374,973
R01 · FY2022 · NS · contact PI
Xenon gas treatment to modulate microglia in neurodegenerative diseases$313,552
R41 · FY2022 · AG
Targeting the miR-155 and APOE-TREM2 pathways to restore dysfunctional microglia in Alzheimer’s disease$809,297
R01 · FY2021 · AG · contact PI
Xenon gas treatment to modulate microglia in neurodegenerative diseases$499,546
R41 · FY2021 · AG
Restoration of homeostatic microglia in CNS inflammation$374,973
R01 · FY2021 · NS · contact PI
Targeting the miR-155 and APOE-TREM2 pathways to restore dysfunctional microglia in Alzheimer's disease$809,297
R01 · FY2020 · AG · contact PI
Microglial mechanisms of postoperative CNS inflammation and cognitive decline$506,483
R01 · FY2020 · AG
Restoration of homeostatic microglia in CNS inflammation$374,973
R01 · FY2020 · NS · contact PI
Targeting the miR-155 and APOE-TREM2 pathways to restore dysfunctional microglia in Alzheimer’s disease$813,171
R01 · FY2019 · AG · contact PI
Microglial mechanisms of postoperative CNS inflammation and cognitive decline$502,438
R01 · FY2019 · AG
Role of Microglia in Retinitis Pigementosa$454,680
R01 · FY2019 · EY
Restoration of homeostatic microglia in CNS inflammation$374,973
R01 · FY2019 · NS · contact PI
Identification of exosome signature in serum from ALS patients$242,406
R21 · FY2019 · NS · contact PI
Role of Microglia in Retinitis Pigementosa$122,264
R01 · FY2019 · EY
Targeting the miR-155 and APOE-TREM2 pathways to restore dysfunctional microglia in Alzheimer’s disease$812,962
R01 · FY2018 · AG · contact PI
Microglial mechanisms of postoperative CNS inflammation and cognitive decline$502,647
R01 · FY2018 · AG
Role of Microglia in Retinitis Pigementosa$454,680
R01 · FY2018 · EY
Mechanism of regulation of CNS inflammation by microglia$342,657
R01 · FY2018 · NS · contact PI
Identification of exosome signature in serum from ALS patients$300,740
R21 · FY2018 · NS · contact PI
Identification of MicroRNA and Proteomics in immune cells and plasma in ALS$220,238
R21 · FY2018 · NS · contact PI
Targeting the miR-155 and APOE-TREM2 pathways to restore dysfunctional microglia in Alzheimer’s disease$828,613
R01 · FY2017 · AG · contact PI
Microglial mechanisms of postoperative CNS inflammation and cognitive decline$499,461
R01 · FY2017 · AG
Role of Microglia in Retinitis Pigementosa$471,550
R01 · FY2017 · EY
Mechanism of regulation of CNS inflammation by microglia$341,258
R01 · FY2017 · NS · contact PI
Identification of MicroRNA and Proteomics in immune cells and plasma in ALS$283,989
R21 · FY2017 · NS · contact PI
Microglial mechanisms of postoperative CNS inflammation and cognitive decline$167,579
R01 · FY2017 · AG
Microglial mechanisms of postoperative CNS inflammation and cognitive decline$499,660
R01 · FY2016 · AG
Mechanism of regulation of CNS inflammation by microglia$354,375
R01 · FY2016 · NS · contact PI
Mechanism of regulation of CNS inflammation by microglia$344,068
R01 · FY2015 · NS · contact PI
Mechanism of regulation of CNS inflammation by microglia$343,326
R01 · FY2014 · NS · contact PI