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Celeste Marie Karch

Washington University

$19,357,585
Attributed
$33,516,116
Total exposure
16
Grants
12
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $8.2M · FY201425
$10M$7.5M$5M$2.5M$0
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$42,548,383 · 17

By mechanism

U54$11,681,128 · 3
R01$10,769,297 · 3
U01$8,232,263 · 1
U19$4,735,080 · 2
RF1$3,355,622 · 2
P30$1,929,932 · 3

Top collaborators

Most similar at Washington University

Same institution · by research overlap

Others in their field

Top investigators on “Alzheimer&Apos

Research focus

Alzheimer&AposS DiseaseMolecularBrainNeuronsGenesTau ProteinsInduced Pluripotent Stem CellMutationPathologicCellsGenomicsNerve DegenerationEventPathogenesisVariantPathway InteractionsTranscriptomicsGeneticRisk VariantResourcesTranscriptome SequencingBrain TissueBiological Models

Grant awards (52)

Tau Metabolism in FTD: From Gene Mutations to Molecular Chaperones and Lysosomal Proteases$1,806,742
U54 · FY2025 · NS
Identification and Characterization of Cell-Specific Transposable Elements Implicated on Alzheimer Disease and Healthy Aging$1,773,745
R01 · FY2025 · AG
iPSC-based Model to Study Frontotemporal Dementia Due to MAPT Mutation$1,540,579
RF1 · FY2025 · NS
Investigating the Functional Impact of AD Risk Genes on Neuro-Vascular Interactions$1,514,673
U01 · FY2025 · AG
Human iPSC Models Core$749,642
U19 · FY2025 · AG · contact PI
Project 2: Tau metabolism: Quantifying tau half-life and secretion$468,009
U54 · FY2025 · NS · contact PI
Biomarker Core$342,105
P30 · FY2025 · AG · contact PI
Identification and Characterization of Cell-Specific Transposable Elements Implicated on Alzheimer Disease and Healthy Aging$1,809,944
R01 · FY2024 · AG
Tau Metabolism in FTD: From Gene Mutations to Molecular Chaperones and Lysosomal Proteases$1,806,742
U54 · FY2024 · NS
Investigating the Functional Impact of AD Risk Genes on Neuro-Vascular Interactions$1,573,956
U01 · FY2024 · AG
Human iPSC Models Core$733,612
U19 · FY2024 · AG · contact PI
Targeting Tau Proteoforms in Frontotemporal Dementia$575,398
R01 · FY2024 · NS · contact PI
Project 2: Tau metabolism: Quantifying tau half-life and secretion$468,009
U54 · FY2024 · NS · contact PI
Core F: Biomarker$275,625
P30 · FY2024 · AG · contact PI
Identification and Characterization of Cell-Specific Transposable Elements Implicated on Alzheimer Disease and Healthy Aging$1,809,944
R01 · FY2023 · AG
Tau Metabolism in FTD: From Gene Mutations to Molecular Chaperones and Lysosomal Proteases$1,806,742
U54 · FY2023 · NS
Investigating the Functional Impact of AD Risk Genes on Neuro-Vascular Interactions$1,603,401
U01 · FY2023 · AG
Project 2: Tau metabolism: Quantifying tau half-life and secretion$770,562
U54 · FY2023 · NS · contact PI
Human iPSC Models Core$665,778
U19 · FY2023 · AG · contact PI
Defining the Mechanisms by Which MS4A Genes Regulate TREM2 in Alzheimer Disease$544,079
R01 · FY2023 · AG · contact PI
Core F: Biomarker$505,011
P30 · FY2023 · AG · contact PI
Dominantly Inherited Alzheimer Network: Project 1$340,272
U19 · FY2023 · AG · contact PI
Investigating the Functional Impact of AD Risk Genes on Neuro-Vascular Interactions$93,149
U01 · FY2023 · AG
Identification and Characterization of Cell-Specific Transposable Elements Implicated on Alzheimer Disease and Healthy Aging$1,846,196
R01 · FY2022 · AG
Tau Metabolism in FTD: From Gene Mutations to Molecular Chaperones and Lysosomal Proteases$1,803,439
U54 · FY2022 · NS
Investigating the Functional Impact of AD Risk Genes on Neuro-Vascular Interactions$1,635,911
U01 · FY2022 · AG
Human iPSC Models Core$670,976
U19 · FY2022 · AG · contact PI
Defining the Mechanisms by Which MS4A Genes Regulate TREM2 in Alzheimer Disease$567,704
R01 · FY2022 · AG · contact PI
Project 2: Tau metabolism: Quantifying tau half-life and secretion$469,603
U54 · FY2022 · NS · contact PI
Dominantly Inherited Alzheimer Network: Project 1$338,002
U19 · FY2022 · AG · contact PI
Core F: Biomarker$275,625
P30 · FY2022 · AG · contact PI
Investigating the Functional Impact of AD Risk Genes on Neuro-Vascular Interactions$121,788
U01 · FY2022 · AG
Investigating the Functional Impact of AD Risk Genes on Neuro-Vascular Interactions$31,078
U01 · FY2022 · AG
Targeting Tau Proteoforms in Frontotemporal Dementia$1,815,043
RF1 · FY2021 · NS · contact PI
Tau Metabolism in FTD: From Gene Mutations to Molecular Chaperones and Lysosomal Proteases$1,808,602
U54 · FY2021 · NS
Investigating the Functional Impact of AD Risk Genes on Neuro-Vascular Interactions$1,658,307
U01 · FY2021 · AG
Brain Single-nuclei and iPS-derived cells transcriptomic analysis to define the contribution of neuronal and glial pathw$719,094
R56 · FY2021 · AG
Dominantly Inherited Alzheimer Network: Project 1$583,896
U19 · FY2021 · AG · contact PI
Defining the Mechanisms by Which MS4A Genes Regulate TREM2 in Alzheimer Disease$567,704
R01 · FY2021 · AG · contact PI
Project 2: Tau metabolism: Quantifying tau half-life and secretion$472,678
U54 · FY2021 · NS · contact PI
Core F: Biomarker$264,125
P30 · FY2021 · AG · contact PI
Defining the Mechanisms by Which MS4A Genes Regulate TREM2 in Alzheimer Disease$629,791
R01 · FY2020 · AG · contact PI
Dominantly Inherited Alzheimer Network: Project 1$324,222
U19 · FY2020 · AG · contact PI
Core F: Biomarker$267,441
P30 · FY2020 · AG · contact PI
Defining the Mechanisms by Which MS4A Genes Regulate TREM2 in Alzheimer Disease$644,792
R01 · FY2019 · AG · contact PI
Targeting Tau Proteoforms in Frontotemporal Dementia$558,119
R56 · FY2019 · NS · contact PI
Dominantly Inherited Alzheimer Network: Project 1$328,680
U19 · FY2019 · AG · contact PI
GENETIC DISRUPTION OF TAU METABOLISM IN TAUOPATHIES$113,700
K01 · FY2018 · AG · contact PI
GENETIC DISRUPTION OF TAU METABOLISM IN TAUOPATHIES$113,700
K01 · FY2017 · AG · contact PI
GENETIC DISRUPTION OF TAU METABOLISM IN TAUOPATHIES$113,700
K01 · FY2016 · AG · contact PI
GENETIC DISRUPTION OF TAU METABOLISM IN TAUOPATHIES$113,700
K01 · FY2015 · AG · contact PI
GENETIC DISRUPTION OF TAU METABOLISM IN TAUOPATHIES$113,048
K01 · FY2014 · AG · contact PI