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David A Agard

University Of California San Francisco

$26,371,232
Attributed
$29,949,734
Total exposure
39
Grants
29
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $8.7M · FY200525
$10M$7.5M$5M$2.5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$38,982,001 · 40

By mechanism

U54$11,009,344 · 3
R01$7,724,942 · 2
U19$5,661,828 · 1
T32$5,100,209 · 1
R35$3,607,619 · 1
U01$3,206,170 · 1

Most similar at University Of California San Francisco

Same institution · by research overlap

Others in their field

Top investigators on “Proteins

Research focus

ProteinsComplexStructureMicrotubulesCryoelectron MicroscopyResolutionIn VitroTubulinIn VivoMolecularCellsCentrosomeBiochemicalRegulationInsightTomographyStructural BiologyBaseProtein ComplexGrantFundingCytoskeletonLinkMolecular Chaperones

Grant awards (101)

Tau Metabolism in FTD: From Gene Mutations to Molecular Chaperones and Lysosomal Proteases$1,806,742
U54 · FY2025 · NS
Core B: Macromolecular and Cellular Structure Core$403,611
U54 · FY2025 · NS · contact PI
Tau Metabolism in FTD: From Gene Mutations to Molecular Chaperones and Lysosomal Proteases$1,806,742
U54 · FY2024 · NS
Core B: Macromolecular and Cellular Structure Core$403,611
U54 · FY2024 · NS · contact PI
Chaperone protection in Lewy body and Alzheimer’s dementias: determining the structural, molecular and cellular mechanisms of a novel, non-canonical Hsp70 action blocking a-synuclein oligomerization$251,970
R21 · FY2024 · AG
Tau Metabolism in FTD: From Gene Mutations to Molecular Chaperones and Lysosomal Proteases$1,806,742
U54 · FY2023 · NS
Core B: Macromolecular and Cellular Structure Core$403,611
U54 · FY2023 · NS · contact PI
Chaperone protection in Lewy body and Alzheimer’s dementias: determining the structural, molecular and cellular mechanisms of a novel, non-canonical Hsp70 action blocking a-synuclein oligomerization$201,875
R21 · FY2023 · AG
Structural biology core$5,661,828
U19 · FY2022 · AI · contact PI
Tau Metabolism in FTD: From Gene Mutations to Molecular Chaperones and Lysosomal Proteases$1,803,439
U54 · FY2022 · NS
Structure and Mechanism: Hsp90 proteostasis, cilia biogenesis and the jumbo phage “nucleus”$845,077
R35 · FY2022 · GM · contact PI
Core B: Macromolecular and Cellular Structure Core$407,574
U54 · FY2022 · NS · contact PI
Tau Metabolism in FTD: From Gene Mutations to Molecular Chaperones and Lysosomal Proteases$1,808,602
U54 · FY2021 · NS
Structure and Mechanism: Hsp90 proteostasis, cilia biogenesis and the jumbo phage “nucleus”$867,180
R35 · FY2021 · GM · contact PI
Core B: Macromolecular and Cellular Structure Core$358,670
U54 · FY2021 · NS · contact PI
Structure & Mechanism: microtubule nucleation, centrosomes, phage cytoskeleton$716,957
R35 · FY2020 · GM · contact PI
Acquisition of Leica EM ICE High Pressure Freezer for cryoTomography$248,410
R35 · FY2020 · GM · contact PI
Structure & Mechanism: microtubule nucleation, centrosomes, phage cytoskeleton$427,174
R35 · FY2019 · GM · contact PI
Structure & Mechanism: microtubule nucleation, centrosomes, phage cytoskeleton$106,028
R35 · FY2019 · GM · contact PI
The Structure and Regulation of Microtubule Nucleation by y-tubulin$301,347
P01 · FY2018 · GM · contact PI
Structure & Mechanism: microtubule nucleation, centrosomes, phage cytoskeleton$194,452
R35 · FY2018 · GM · contact PI
The Structure and Regulation of Microtubule Nucleation by y-tubulin$306,930
P01 · FY2017 · GM · contact PI
Structure & Mechanism: microtubule nucleation, centrosomes, phage cytoskeleton$202,340
R35 · FY2017 · GM · contact PI
Centrosome structure and mechanism of MT nucleation by gamma-tubulin complexes$479,841
R01 · FY2016 · GM · contact PI
Characterization of a bacteriophage tubulin involved in viral replication$416,353
R01 · FY2016 · GM
The Structure and Regulation of Microtubule Nucleation by y-tubulin$280,864
P01 · FY2016 · GM · contact PI
The Structure and Regulation of Microtubule Nucleation by y-tubulin$199,592
P01 · FY2016 · GM · contact PI
Structure & Mechanism: microtubule nucleation, centrosomes, phage cytoskeleton$1
R35 · FY2016 · GM · contact PI
Centrosome structure and mechanism of MT nucleation by gamma-tubulin complexes$479,084
R01 · FY2015 · GM · contact PI
Characterization of a bacteriophage tubulin involved in viral replication$418,998
R01 · FY2015 · GM
The Structure and Regulation of Microtubule Nucleation by y-tubulin$172,708
P01 · FY2015 · GM · contact PI
Structural Basis of Protein Homeostasis$1,079,168
U01 · FY2014 · GM
Centrosome structure and mechanism of MT nucleation by gamma-tubulin complexes$476,814
R01 · FY2014 · GM · contact PI
Characterization of a bacteriophage tubulin involved in viral replication$421,280
R01 · FY2014 · GM
The Structure and Regulation of Microtubule Nucleation by y-tubulin$190,357
P01 · FY2014 · GM · contact PI
Structural Basis of Protein Homeostasis$1,039,242
U01 · FY2013 · GM
Centrosome structure and mechanism of MT nucleation by gamma-tubulin complexes$474,796
R01 · FY2013 · GM · contact PI
Characterization of a bacteriophage tubulin involved in viral replication$388,864
R01 · FY2013 · GM
Structural Basis of Protein Homeostasis$1,087,760
U01 · FY2012 · GM
Structural Biology Training Program$459,021
T32 · FY2012 · GM · contact PI
Microtubule Nucleation: Structure & Mechanism$432,572
R01 · FY2012 · GM · contact PI
Structural Biology Training Program$484,416
T32 · FY2011 · GM · contact PI
Microtubule Nucleation: Structure & Mechanism$431,729
R01 · FY2011 · GM · contact PI
REFINING THE STRUCTURE OF THE SMALL GAMMA TUBULIN COMPLEX$28,839
P41 · FY2011 · RR · contact PI
CRYO-EM RECONSTRUCTION OF THE HUMAN HSP90:HOP COMPLEX$6,427
P41 · FY2011 · RR · contact PI
STRUCTURAL BASIS FOR MICROTUBULE NUCLEATION BY THE GAMMA-TUBULIN SMALL COMPLEX$6,427
P41 · FY2011 · RR · contact PI
Structural Biology Training Program$478,973
T32 · FY2010 · GM · contact PI
Microtubule Nucleation: Structure & Mechanism$435,262
R01 · FY2010 · GM · contact PI
LEGINON TOMOGRAPHY$12,918
P41 · FY2010 · RR · contact PI
STRUCTURAL BASIS FOR MICROTUBULE NUCLEATION BY THE GAMMA-TUBULIN SMALL COMPLEX$12,918
P41 · FY2010 · RR · contact PI
REFINING THE STRUCTURE OF THE SMALL GAMMA TUBULIN COMPLEX$9,629
P41 · FY2010 · RR · contact PI
CRYO-EM RECONSTRUCTION OF THE HUMAN HSP90:HOP COMPLEX$6,453
P41 · FY2010 · RR · contact PI
Structural Biology Training Program$476,329
T32 · FY2009 · GM · contact PI
Microtubule Nucleation: Structure & Mechanism$360,522
R01 · FY2009 · GM · contact PI
Microtubule Nucleation: Structure & Mechanism$26,109
R01 · FY2009 · GM · contact PI
STRUCTURAL BASIS FOR MICROTUBULE NUCLEATION BY THE GAMMA-TUBULIN SMALL COMPLEX$12,892
P41 · FY2009 · RR · contact PI
TECH R&D CORE SUPPORT FOR AIDS RESEARCH$8,569
P41 · FY2009 · RR · contact PI
LEGINON TOMOGRAPHY$6,453
P41 · FY2009 · RR · contact PI
EXAMINING THE ROLE OF THE ATPASE CYCLE OF HSP90 IN CONFORMATION AND COMPLEX FORM$213
P41 · FY2009 · RR · contact PI
Structural Biology Training Program$473,685
T32 · FY2008 · GM · contact PI
3D Structure and Mechanism of Centrosome Function$300,904
R01 · FY2008 · GM · contact PI
LEGINON TOMOGRAPHY$37,872
P41 · FY2008 · RR · contact PI
REFINING THE STRUCTURE OF THE SMALL GAMMA TUBULIN COMPLEX$19,466
P41 · FY2008 · RR · contact PI
EXAMINING THE ROLE OF THE ATPASE CYCLE OF HSP90 IN CONFORMATION AND COMPLEX FORM$1,923
P41 · FY2008 · RR · contact PI
Structural Biology Training Program$362,695
T32 · FY2007 · GM · contact PI
3D Structure and Mechanism of Centrosome Function$324,654
R01 · FY2007 · GM · contact PI
LEGINON TOMOGRAPHY$53,669
P41 · FY2007 · RR · contact PI
REFINING THE STRUCTURE OF THE SMALL GAMMA TUBULIN COMPLEX$12,507
P41 · FY2007 · RR · contact PI
EXAMINING THE ROLE OF THE ATPASE CYCLE OF HSP90 IN CONFORMATION AND COMPLEX FORM$2,777
P41 · FY2007 · RR · contact PI
SAXS STUDY OF NUCLEOTIDE-DEPENDENT CONFORMATIONAL CHANGE IN AB-TUBULIN AND HSP90$199
P41 · FY2007 · RR · contact PI
Structural Biology Training Program$368,637
T32 · FY2006 · GM · contact PI
3D Structure and Mechanism of Centrosome Function$315,644
R01 · FY2006 · GM · contact PI
NUCLEOTIDE-DEPENDENT CONFORMATIONAL CHANGE IN ALPHA/BETA-TUBULIN & HSP90$17,817
P41 · FY2006 · RR · contact PI
LEGINON TOMOGRAPHY$12,642
P41 · FY2006 · RR · contact PI
SAXS STUDY OF NUCLEOTIDE-DEPENDENT CONFORMATIONAL CHANGE IN AB-TUBULIN AND HSP90$2,367
P41 · FY2006 · RR · contact PI
EXAMINING THE ROLE OF THE ATPASE CYCLE OF HSP90 IN CONFORMATION AND COMPLEX FORM$219
P41 · FY2006 · RR · contact PI
Structural Biology Training Program$368,637
T32 · FY2005 · GM
3D Structure and Mechanism of Centrosome Function$299,349
R01 · FY2005 · GM
REFINING THE STRUCTURE OF THE SMALL GAMMA TUBULIN COMPLEX$17,530
P41 · FY2005 · RR
STRUCTURAL CHAR OF LYTIC PROTEASE FOLDING INTERMEDIATE BY CROSS LINKING &MS$24
P41 · FY2005 · RR
Structural Biology Training Program$368,637
T32 · FY2004 · GM
3D STRUCTURE AND FUNCTION OF CENTROSOMES AND CHROMOSOMES$101,001
R01 · FY2004 · GM
THE STRUCTURE OF THE SMALL GAMMA TUBULIN COMPLEX$60,430
P41 · FY2004 · RR
STRUCTURAL CHAR OF LYTIC PROTEASE FOLDING INTERMEDIATE$363
P41 · FY2004 · RR
Structural Biology Training Program$358,217
T32 · FY2003 · GM
3D STRUCTURE AND FUNCTION OF CENTROSOMES AND CHROMOSOMES$290,588
R01 · FY2003 · GM
STRUCTURAL BIOLOGY TRAINING PROGRAM$317,272
T32 · FY2002 · GM
3D STRUCTURE AND FUNCTION OF CENTROSOMES AND CHROMOSOMES$290,874
R01 · FY2002 · GM
OXIDATIVE FOLDING OF POLYPEPTIDES$0
P41 · FY2002 · RR
CORE--NMR FACILITY$0
P01 · FY2002 · DK
STRUCTURE AND DYNAMICS OF THE ESTROGEN RECEPTOR$0
P01 · FY2002 · DK
STRUCTURAL BIOLOGY TRAINING PROGRAM$301,176
T32 · FY2001 · GM
3D STRUCTURE AND FUNCTION OF CENTROSOMES AND CHROMOSOMES$279,734
R01 · FY2001 · GM
CORE--NMR FACILITY$0
P01 · FY2001 · DK
OXIDATIVE FOLDING OF POLYPEPTIDES$0
P41 · FY2001 · RR
STRUCTURE AND DYNAMICS OF THE ESTROGEN RECEPTOR$0
P01 · FY2001 · DK
GATAN IMAGING ENERGY FILTER WITH CCD CAMERA FOR IVEM$399,823
S10 · FY2000 · RR
STRUCTURAL BIOLOGY TRAINING PROGRAM$282,514
T32 · FY2000 · GM
3D STRUCTURE AND FUNCTION OF CENTROSOMES AND CHROMOSOMES$279,970
R01 · FY2000 · GM
OXIDATIVE FOLDING OF POLYPEPTIDES$9,880
P41 · FY2000 · RR
FASEB CONFERENCE: PROTEIN FOLDING AND ASSEMBLY IN CELLS$5,000
R13 · FY2000 · GM