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Puerto Rico Science, Technology, And Research Trust

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$963,360
Total funding
1
Grants

Funding mix

By agency

DOD$963,360 · 1

By mechanism

—$963,360 · 1

Investigators at Puerto Rico Science, Technology, And Research Trust

Investigator-initiatedAll funding

InvestigatorsiAttributed = a PI's even-split share of each grant — a $1M grant with 2 PIs counts $500K each.
Exposure= the full size of every grant they're on ($1M each).

Rising Stars

First grant in the last 5 yrs

Not enough data

Emerging Leaders

6–10 yrs in

Not enough data

All-Time

Most funded here, all years

Not enough data

Largest grants

THE OBJECTIVE FOR THE PROPOSED WORK IS TO DEVELOP METHODS TO FACILITATE THE QUICK IDENTIFICATION OF NATURAL PRODUCTS IN EXTRACTS AND THE QUICK IDENTIFICATION OF HUMAN PROTEIN TARGETS. BY COMBINING THE ETHOS OF BIG DATA AND -OMICS TECHNOLOGIES WE SHOULD BE ABLE (1) TO ESTABLISH THE CHEMICAL TAXONOMY OF ACTIVE COMPOUNDS IN A NATURAL PRODUCT MIXTURE USING HIGH-RESOLUTION MASS SPECTROMETRY WITH MOLECULAR NETWORKING AND (2) TO IDENTIFY THE HUMAN PROTEIN TARGETS WITHIN THE MIXTURE USING A HUMAN PROTEOME ARRAY CHIP MADE BY PUERTO RICO-BASED COMPANY CDI LABORATORIES. THE PROPOSAL ADDRESSES A CURRENT GAP WITHIN THE ASSIGNED THRUST AREA 7 THROUGH EXPANSION OF THE RESOURCES AND CAPABILITIES AVAILABLE FOR DRUG DISCOVERY AND DEVELOPMENT PIPELINES, AS WELL AS MEDICAL COUNTERMEASURE DEVELOPMENT PLATFORMS. THE TECHNICAL APPROACH FOR THIS PROJECT IS AN INNOVATIVE ONE, WHICH INVOLVES DEVELOPING METHODS TO FACILITATE THE QUICK IDENTIFICATION OF NATURAL PRODUCTS IN EXTRACTS AND THE QUICK IDENTIFICATION OF HUMAN PROTEIN TARGETS.$963,360
· FY2025 · Defense Threat Reduction Agency