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Arkansas State University

State University, AR

$12,764,198

Total funding

35

Grants

Funding over time

peak $2.9M · FY2006–25

$5M$3.8M$2.5M$1.3M$0

'06

'07

'08

'09

'10

'11

'12

'13

'14

'15

'16

'17

'18

'19

'20

'21

'22

'23

'24

'25

Funding mix

By agency

DOE$4,706,916 · 4

USDA$3,176,476 · 20

NIH$3,169,069 · 9

DOD$1,711,736 · 2

By mechanism

—$9,595,129 · 26

R15$1,836,360 · 5

R01$700,556 · 2

R21$361,760 · 1

R03$270,393 · 1

Investigators at Arkansas State University

Investigator-initiated All funding

Investigatorsi

Rising Stars

First grant in the last 5 yrs

1Mohammad Abrar Alam$419,1611 gr

Emerging Leaders

6–10 yrs in

1Robert Colquhoun Shields$637,9272 gr 2Guolei Zhou$419,1901 gr

All-Time

Most funded here, all years

1Robert Colquhoun Shields$637,9272 gr 2Guolei Zhou$419,1901 gr 3Mohammad Abrar Alam$419,1611 gr

Largest grants

NEW CONGRESSIONALLY DIRECTED PROJECT AWARD TO ARKANSAS STATE UNIVERSITY ENTITLED, "ETHANOL FROM AGRICULTURE FOR ARKANSAS AND AMERICA."$2,927,500

· FY2008 · Department of Energy

ETHANOL FROM AGRICULTURE FOR ARKANSAS AND AMERICA$1,451,084

· FY2009 · Department of Energy

BECK PRIDE CENTER - AN EFFECTIVE SOLUTION FOR COMBAT INJURED STUDENT VETERANS$1,360,912

· FY2011 · Department of Defense

ALTERNATIVES TO METHYL BROMIDE FOR EFFECTIVE INTEGRATED PEST MANAGEMENT IN RICE MILLS$475,638

· FY2014 · National Institute of Food and Agriculture

INTEGRATED PEST MANAGEMENT PROGRAMS TO REDUCE RELIANCE ON METHYL BROMIDE FUMIGATION IN RICE MILLS$450,502

· FY2011 · National Institute of Food and Agriculture

** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** THIS IS AN INTEGRATED PROJECT SUBMITTED BY OUR INTERDISCIPLINARY RESEARCH TEAM CONSISTING OFPRINCIPAL INVESTIGATORS FROM THREE COLLABORATIVE INSTITUTIONS IN TWO STATES (ARKANSAS AND KANSAS).OUR PROJECT ADDRESSES THE PRIMARY GOAL AND OBJECTIVE OF THE METHYL BROMIDE TRANSITION PROGRAMBY RESEARCHING THE IMPLEMENTATION OF PRACTICAL INTEGRATED PEST MANAGEMENT (IPM) SYSTEMS TOPROTECT POST-HARVEST BAGGED COMMODITIES DURING TRANSPORTATION IN SHIPPING CONTAINERS. WE AREPROPOSING TO OPTIMIZE FUMIGANT APPLICATION METHODS FOR PHOSPHINEBASED ONEXPERIMENTS IN SHIPPING CONTAINERS AND BY DEVELOPING AND VALIDATING A COMPUTATIONAL FLUIDDYNAMICS MODEL OF PHOSPHINE DISTRIBUTION INSIDE THE CONTAINERS. AT THE SAME TIME, WE WILLEVALUATE THE EFFECTIVENESS OF PRE-LOADING APPLICATIONS OF CONTACT INSECTICIDES IN SHIPPINGCONTAINERS AND INSECTICIDE-INCORPORATED PACKAGING AT SUPPRESSING INSECT POPULATIONS ANDPROTECTING COMMODITIES. A COMPREHENSIVE COST/BENEFIT ANALYSIS FOR EACH OF THESE IPMTECHNOLOGIES ALONE AND IN COMBINATION WILL BE CONDUCTED. THE FINAL AIM IS TO TRANSFER THISINFORMATION ON BEST PRACTICES TO UNITED STATES AND INTERNATIONAL STAKEHOLDERS INCLUDING FOOD ANDFEED INDUSTRIES AND HUMANITARIAN AID AGENCIES TO BETTER IMPLEMENT IPM PRACTICES. WITHIN THESEBROAD OBJECTIVES, WE WILL SHOW HOW COMBINING IPM TOOLS COULD REDUCE INFESTATION FROM STOREDPRODUCT INSECTS ECONOMICALLY COMPARED TO FUMIGATION ALONE.$420,391

· FY2023 · National Institute of Food and Agriculture

Phosphor-regulation of CAP1 Functions in Cell Adhesion and Migration$419,190

R15 · FY2019 · GM

Systematic Functional Genomics Analysis of the Oral Pathogen Streptococcus Mutans$419,161

R15 · FY2024 · DE

Dual localization of angiopoietin like protein 4 in the extracellular milieu and nucleus regulates the hematogenous brain metastasis of triple negative breast cancer$408,259

R15 · FY2025 · CA

Engineering novel designer biologics in plant cells for oral treatment of ulcerative colitis$395,242

R15 · FY2021 · DK

Mechanisms of Integrative and Conjugative Elements in Oral Bacteria$360,555

R01 · FY2024 · DE

PSEUDO-CONTINUUM SOURCE VOLUME ISOTOPE EFFECT ABSORPTION SPECTRA FOR FIELDABLE MEASUREMENT OF URANIUM AND PLUTONIUM ENRICHMENT$350,824

· FY2016 · Defense Threat Reduction Agency

FUNDAMENTAL STUDIES OF SOILING AND CEMENTATION OF PV COVER GLASS MATERIALS: ADDRESSING RELIABILITY WITH ADVANCED X-RAY SCATTERING/SPECTROSCOPY AND FIRST PRINCIPLES MODELING$341,113

· FY2020 · Department of Energy

HuR regulates Th17 cells for promoting autoimmune neuroinflammation$340,000

R01 · FY2015 · AI

PHYTOPHTHORA STEM AND ROOT ROT (PSR), CAUSED BY THE OOMYCETEPHYTOPHTHORA SOJAE, CAUSES SIGNIFICANT LOSSES IN SOYBEAN.P. SOJAESECRETES EFFECTOR PROTEINS CODED BY AVIRULENCE (AVR) GENES TO SUCCESSFULLY INFECT SOYBEAN. PSR IS PRIMARILY MANAGED BY PLANTING VARIETIES WITH RESISTANT GENES (RPS) THAT PREVENT INFECTION. HOWEVER, THE DURABILITY OF THESE GENES IS LIMITED TO 8-15 YEARS BECAUSE NEW VIRULENT PATHOTYPES EVOLVE TO BECOME VIRULENT AGAINST THERPSGENE. CONSEQUENTLY, NOVEL WAYS TO MANAGE THIS PSR ARE NEEDED.P. SOJAEIS ATTRACTED TO THE SOYBEAN RHIZOSPHERE BY ROOT EXUDATES. ROOT EXUDES ALSO TO ATTRACT BENEFICIAL MICROBES TO THE RHIZOSPHERE AND THESE MICROBES MAY SUPPRESS SOIL-BORNE PATHOGENS LIKEP. SOJAE. WE HYPOTHESIZE THATP. SOJAEUSES ITS EFFECTOR PROTEINS TOMANIPULATE THE HOST ROOT MICROBIOME FOR SUCCESSFUL INFECTION.STUDYING THE INTERACTION OF EFFECTOR PROTEINS WITH THE RHIZOSPHERE MICROBIOME MAY HELP US DISCOVER NOVEL BIO-BASED MATERIALS FOR BIOCONTROL OF PSR AND CONTRIBUTE TOTHE LONG-RANGE IMPROVEMENT IN AND SUSTAINABILITY OF US AGRICULTURE AND FOOD SYSTEMS. IN THE PROPOSED STUDY, WE WILL INVESTIGATE CHANGES IN ABUNDANCE, DIVERSITY, AND FUNCTION OF THE SOYBEAN ROOT MICROBIOME OVER TIME DURING COMPATIBLE AND INCOMPATIBLE SOYBEAN-P. SOJAEINTERACTIONS WITH TWO SOYBEAN GENOTYPES. THIS AIM ALIGNS WELL WITH THE PROGRAM AREA PRIORITY OF STUDYING FUNCTIONS OFAGRICULTURAL MICROBIOMES IN PLANT SYSTEMS AND NATURAL RESOURCES. THE OUTCOME OF THIS PROJECT WILL STRENGTHEN OUR RESEARCH PROGRAM BY CONTRIBUTING TO OUR UNDERSTANDING OF HOWP. SOJAEALTERS THE SOYBEAN ROOT MICROBIOME FOR INFECTION AND COLONIZATION. IN ADDITION, THIS STUDY WILL BUILD RESOURCES AND EXPERTISE FOR US TO BE MORE COMPETITIVE FOR EXTERNAL GRANT APPLICATIONS (NSF/USDA) TO STUDY BENEFICIAL AND PATHOGENIC MICROBE INTERACTIONS.$299,989

· FY2022 · National Institute of Food and Agriculture

**AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** FINDING NOVEL GENETIC TARGETS TO IMPROVE CROP YIELDS AND MAINTAIN QUALITY IS INCREASINGLY IMPORTANT AS PLANT BREEDERS RACE TO KEEP UP INCREASINGLY UNPREDICTABLE CLIMATES, RISING COSTS OF AGRICULTURAL INPUTS, AND THE NEED TO CONSERVE NATURAL RESOURCES. THIS PROJECT FOCUSES ON TWO THEMES TOWARDS ACCELERATING PLANT BREEDING EFFORTS: 1) DEVELOPMENT OF NEW APPROACHES FOR CHARACTERIZING PLANT TRAITS FROM HIGH RESOLUTION DRONE IMAGERY AND 2) LEVERAGING MACHINE LEARNING AND ARTIFICIAL INTELLIGENCE TO IDENTIFY GENES IMPORTANT FOR IMPROVED CROP PERFORMANCE UNDER LOW INPUT ENVIRONMENTS. OUR PROPOSED RESEARCH WILL DETERMINE WHETHER GENOME ASSOCIATIONS WITH MULTIPLE IMAGES, INSTEAD OF JUST A SINGLE IMAGE, COULD HELP REVEAL NOVEL TARGETS FOR GENETIC IMPROVEMENT OF RICE, A CRITICALLY IMPORTANT STAPLE FOOD. RICE PRODUCTION CAN HAVE OUTSIZED ENVIRONMENTAL IMPACTS DUE TO WATER-INTENSIVE CULTIVATION SYSTEMS AND GREENHOUSE GAS EMISSIONS, AND SO DEVELOPMENT OF VARIETIES THAT PERFORM WELL UNDER LOW-INPUT CONDITIONS IS A TOP PRIORITY. ADDITIONALLY, WE WILL DETERMINE WHETHER GENETIC VARIANTS ASSOCIATED WITH IMPROVED NITROGEN AND WATER USE EFFICIENCY COULD BE DETERMINED FROM EXISTING ECOLOGICAL AND GENOMIC DATASETS. OUR MODEL PUBLIC-PRIVATE PARTNERSHIP CONTRIBUTES TO THE NATIONAL ARTIFICIAL INTELLIGENCE INITIATIVE THROUGH ITS FOCUS ON INCREASING CROP YIELDS WHILE CONSERVING NATURAL RESOURCES, AND CONTRIBUTES TO THE DESIGN AND VALIDATION OF NOVEL METHODS FOR ANALYSIS AND INTEGRATION OF BIG AGRICULTURAL DATA, ONE OF THE TOP PRIORITIES FOR THE DATA SCIENCE FOR FOOD AND AGRICULTURAL SYSTEMS PROGRAM AREA.DEVELOPMENT OF RICE VARIETIES WITH IMPROVED PERFORMANCE UNDER LOW WATER INPUT MANAGEMENT CONDITIONS WILL HELP TO CONSERVE FRESHWATER RESOURCES IN THE FACE OF INCREASING WATER SCARCITY. ADDITIONALLY, REDUCING FERTILIZER INPUTS THROUGH DEVELOPMENT OF NITROGEN-EFFICIENT RICE VARIETIES AND PRECISION MANAGEMENT TOOLS WILL REDUCE NUTRIENT POLLUTION AND DECREASE GREENHOUSE GAS EMISSIONS IN WATER-LIMITED RICE PRODUCTION SYSTEMS. REDUCED INPUT COSTS FOR IRRIGATION AND FERTILIZER WILL TRANSLATE TO IMPROVED ECONOMIC VIABILITY FOR RICE PRODUCTION, AS COSTS FOR NITROGEN AND WATER INPUTS CONTINUE TO RISE. BEYOND RICE, OUR APPROACH TO IDENTIFYING GENES ASSOCIATED WITH REDUCED INPUTS IN MODERN AGRICULTURAL SYSTEMS COULD BE BROADLY APPLICABLE TO OTHER CROPS AND SYSTEMS.$297,976

· FY2023 · National Institute of Food and Agriculture

CHRONIC DISEASES SUCH AS INFLAMMATORY BOWEL DISEASE, DIABETES, AND OSTEOPOROSIS AFFECT MILLIONS OF AMERICANS AND REQUIRE LONG-TERM TREATMENT WITH EXPENSIVE DRUGS THAT ARE USUALLY DELIVERED BY INJECTION. INJECTIONS ARE NOT ONLY COSTLY AND INCONVENIENT, BUT THEY ALSO DISCOURAGE PATIENTS FROM STAYING ON THEIR MEDICATIONS, WHICH CAN WORSEN HEALTH OUTCOMES AND INCREASE HEALTHCARE COSTS FOR FAMILIES AND COMMUNITIES. FINDING AFFORDABLE, SAFE, AND EASY-TO-USE ALTERNATIVES IS A CRITICAL NEED.THIS PROJECT WILL ESTABLISH PROOF-OF-CONCEPT FOR USING LETTUCE AS A PLATFORM TO PRODUCE AND DELIVER NEXT-GENERATION ORAL BIOLOGICS. LETTUCE IS ALREADY A SAFE, WIDELY CONSUMED CROP, AND IT CAN BE GROWN QUICKLY AND INEXPENSIVELY USING STANDARD AGRICULTURAL PRACTICES. WE WILL TEST NEW WAYS OF ENGINEERING LETTUCE TO PRODUCE PROTEIN-BASED MEDICINES THAT ARE PROTECTED DURING DIGESTION AND RELEASED IN THE INTESTINE WHERE THEY ARE MOST EFFECTIVE. WE WILL USE STANDARD GREENHOUSE PRACTICES TO GROW LETTUCE PLANTS THAT CONTAIN SPECIALLY DESIGNED PROTEINS, THEN EVALUATE HOW WELL THESE PROTEINS ARE MADE, HOW STABLE THEY ARE, AND WHETHER THEY REMAIN ACTIVE AFTER PASSING THROUGH SIMULATED STOMACH AND INTESTINAL CONDITIONS. BY SHOWING THAT LETTUCE CAN SERVE AS A SAFE AND EFFECTIVE CAPSULE FOR ORAL DELIVERY OF MEDICINES, THIS RESEARCH WILL LAY THE FOUNDATION FOR A NEW GENERATION OF AFFORDABLE BIOLOGICS THAT PATIENTS CAN TAKE BY MOUTH INSTEAD OF INJECTIONS. THE ULTIMATE GOAL IS TO IMPROVE HUMAN HEALTH THROUGH MORE ACCESSIBLE TREATMENTS, WHILE ALSO CREATING NEW USES FOR AGRICULTURAL CROPS THAT CAN BENEFIT FARMERS, BIOTECHNOLOGY INDUSTRIES, AND THE LARGER COMMUNITY.$280,305

· FY2025 · National Institute of Food and Agriculture

Nicotine and Development of Autonomic Neurons$194,508

R15 · FY2006 · DA

RTB-mediated delivery: Orchestrating antigen trafficking to enhance cell immunity$191,760

R21 · FY2013 · AI

INVESTIGATIONS OF NEW TECHNOLOGIES FOR THE EARLY-DETECTION AND CONTROL OF W$179,427

· FY2016 · Forest Service