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George A O'Doherty

West Virginia University

$4,408,102
Attributed
$7,049,011
Total exposure
8
Grants
3
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $1.3M · FY200523
$2M$1.5M$1M$500K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23

Funding mix

By agency

NIH$7,049,011 · 8

By mechanism

R01$5,910,424 · 4
R21$951,603 · 2
R03$182,984 · 1
R13$4,000 · 1

Top collaborators

Others in their field

Top investigators on “Analog

Research focus

AnalogPharmaceutical ChemistryLaboratoriesBaseInfectionMulti-Drug ResistanceCarbohydratesSchemeAnti-Infective AgentsModificationStructureAntimicrobialPositioning AttributeSugarFrequenciesPathogenic BacteriaMicrobiologyAcinetobacter BaumanniiEnzymesAntibioticsPseudomonas AeruginosaEmerging Antimicrobial ResistanceCarbapenem-Resistant EnterobacteriaceaePathogen

Grant awards (23)

De Novo Synthesis, and Functional and Structural Characterization of Novel Aminoglycoside Analogues to Bypass Resistance Mechanisms and Optimize Selectivity$757,156
R01 · FY2023 · AI
De Novo Synthesis, and Functional and Structural Characterization of Novel Aminoglycoside Analogues to Bypass Resistance Mechanisms and Optimize Selectivity$765,318
R01 · FY2022 · AI
De Novo Synthesis, and Functional and Structural Characterization of Novel Aminoglycoside Analogues to Bypass Resistance Mechanisms and Optimize Selectivity$772,551
R01 · FY2021 · AI
De Novo Synthesis, and Functional and Structural Characterization of Novel Aminoglycoside Analogues to Bypass Resistance Mechanisms and Optimize Selectivity$815,399
R01 · FY2020 · AI
Apramycin scaffold exploration using novel glycochemistry and SAR studies to enhance activity against Acinetobacter baumannii and other multidrug-resistant Gram-negative pathogens$210,119
R21 · FY2020 · AI
Fusidic acid derivatization to enhance entry into Gram-negative pathogens$209,030
R21 · FY2020 · AI
Targeted modification of the apramycin 2-deoxystreptamine ring to block aminoglycoside modifying enzyme-based inactivation and enhance potency against multidrug-resistant Gram-negative pathogens$82,117
R03 · FY2020 · AI
Apramycin scaffold exploration using novel glycochemistry and SAR studies to enhance activity against Acinetobacter baumannii and other multidrug-resistant Gram-negative pathogens$266,324
R21 · FY2019 · AI
Fusidic acid derivatization to enhance entry into Gram-negative pathogens$266,130
R21 · FY2019 · AI
Targeted modification of the apramycin 2-deoxystreptamine ring to block aminoglycoside modifying enzyme-based inactivation and enhance potency against multidrug-resistant Gram-negative pathogens$100,867
R03 · FY2019 · AI
2013 Carbohydrate GRC$4,000
R13 · FY2013 · GM · contact PI
De Novo Synthesis of Oligosaccharides$304,811
R01 · FY2012 · GM · contact PI
De Novo Synthesis of Oligosaccharides$304,811
R01 · FY2011 · GM · contact PI
De Novo Synthesis of Oligosaccharides$307,890
R01 · FY2010 · GM · contact PI
De Novo Synthesis for MedChem on Sugars$307,546
R01 · FY2010 · GM · contact PI
De Novo Synthesis for MedChem on Sugars$3,254
R01 · FY2010 · GM · contact PI
De Novo Synthesis of Oligosaccharides$293,000
R01 · FY2009 · GM · contact PI
De Novo Synthesis for MedChem on Sugars$293,000
R01 · FY2009 · GM · contact PI
Synthesis of Papulacandins A-D;New Antifungal Analogs$248,200
R01 · FY2005 · GM
Synthesis of Papulacandins A-D;New Antifungal Analogs$248,200
R01 · FY2004 · GM
Synthesis of Papulacandins A-D;New Antifungal Analogs$248,200
R01 · FY2003 · GM
Synthesis of Papulacandins A-D;New Antifungal Analogs$149,619
R01 · FY2002 · GM
Synthesis of Papulacandins A-D;New Antifungal Analogs$91,469
R01 · FY2002 · GM