← Leaderboards
Edward W Yu
Iowa State University
$11,743,923
Attributed
$21,947,149
Total exposure
13
Grants
4
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $3.4M · FY2005–25$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$21,947,149 · 13
By mechanism
R01$20,770,449 · 10
R56$1,093,696 · 2
F32$83,004 · 1
Top collaborators
- James E Kirby9 shared
- Georgiana E Purdy6 shared
- Qijing Zhang6 shared
- Roman Manetsch5 shared
- George A O'Doherty4 shared
- Herbert P. Schweizer4 shared
- Daniel E Goldberg1 shared
- Mary Jackson1 shared
Others in their field
Top investigators on “Resistance”
- Judith S. Currier · University Of California Los Angeles$243,611,225
- Gregory H Reaman · National Childhood Cancer Foundation$217,720,574
- Joseph J. Eron · Univ Of North Carolina Chapel Hill$180,092,958
- Ralph Parchment · Leidos Biomedical Research, Inc.$149,556,948
- Wafaa M. El-Sadr · Columbia University Health Sciences$113,991,858
- Peter C Adamson · National Childhood Cancer Foundation$113,790,601
Research focus
ResistanceStructureProteinsPathogenAntibioticsAntimicrobialInsightInfectionBindingMulti-Drug ResistanceMediatingBaseCellsPathogenic BacteriaMembranePhysiologyStructure-Activity RelationshipPeriplasmSite-Directed MutagenesisMolecularAntibiotic ResistanceCrystallizationDesignPharmaceutical Preparations
Grant awards (42)
Intermembrane transport of lipids and metabolites by mycobacterial MmpL protein complexes$811,396
R01 · FY2025 · AI
Function of PfNCR1 at the PPM/PVM Interface$633,218
R01 · FY2025 · AI
Use of De Novo Synthesis Approaches and Structure-guided Design to Optimize Therapeutic Properties of Streptothricin Class Antimicrobials$761,258
R01 · FY2024 · AI
Emerging multidrug resistance mechanisms in Campylobacter$626,007
R01 · FY2024 · AI
Use of De Novo Synthesis Approaches and Structure-guided Design to Optimize Therapeutic Properties of Streptothricin Class Antimicrobials$766,825
R01 · FY2023 · AI
De Novo Synthesis, and Functional and Structural Characterization of Novel Aminoglycoside Analogues to Bypass Resistance Mechanisms and Optimize Selectivity$757,156
R01 · FY2023 · AI
Emerging antibiotic resistance in Gram-negative pathogens$667,051
R01 · FY2023 · AI · contact PI
Emerging multidrug resistance mechanisms in Campylobacter$629,067
R01 · FY2023 · AI
Use of De Novo Synthesis Approaches and Structure-guided Design to Optimize Therapeutic Properties of Streptothricin Class Antimicrobials$772,231
R01 · FY2022 · AI
De Novo Synthesis, and Functional and Structural Characterization of Novel Aminoglycoside Analogues to Bypass Resistance Mechanisms and Optimize Selectivity$765,318
R01 · FY2022 · AI
Emerging antibiotic resistance in Gram-negative pathogens$667,051
R01 · FY2022 · AI · contact PI
Emerging multidrug resistance mechanisms in Campylobacter$629,067
R01 · FY2022 · AI
Use of De Novo Synthesis Approaches and Structure-guided Design to Optimize Therapeutic Properties of Streptothricin Class Antimicrobials$777,478
R01 · FY2021 · AI
De Novo Synthesis, and Functional and Structural Characterization of Novel Aminoglycoside Analogues to Bypass Resistance Mechanisms and Optimize Selectivity$772,551
R01 · FY2021 · AI
Emerging antibiotic resistance in Gram-negative pathogens$667,051
R01 · FY2021 · AI · contact PI
Emerging multidrug resistance mechanisms in Campylobacter$629,067
R01 · FY2021 · AI
Metabolite modulation of Mtb regulators of cell wall biogenesis$481,646
R01 · FY2021 · AI
Use of De Novo Synthesis Approaches and Structure-guided Design to Optimize Therapeutic Properties of Streptothricin Class Antimicrobials$818,324
R01 · FY2020 · AI
De Novo Synthesis, and Functional and Structural Characterization of Novel Aminoglycoside Analogues to Bypass Resistance Mechanisms and Optimize Selectivity$815,399
R01 · FY2020 · AI
Emerging antibiotic resistance in Gram-negative pathogens$665,756
R01 · FY2020 · AI · contact PI
Emerging multidrug resistance mechanisms in Campylobacter$641,884
R01 · FY2020 · AI
Metabolite modulation of Mtb regulators of cell wall biogenesis$481,646
R01 · FY2020 · AI
Emerging antibiotic resistance in Gram-negative pathogens$678,943
R01 · FY2019 · AI · contact PI
Metabolite modulation of Mtb regulators of cell wall biogenesis$481,646
R01 · FY2019 · AI
Emerging multidrug resistance mechanisms in Campylobacter$617,308
R56 · FY2018 · AI
Metabolite modulation of Mtb regulators of cell wall biogenesis$481,646
R01 · FY2018 · AI
Metabolite modulation of Mtb regulators of cell wall biogenesis$495,146
R01 · FY2017 · AI
Structure and mechanism of the AbgT-family transporters$366,406
R01 · FY2017 · AI · contact PI
Structure and mechanism of the AbgT-family transporters$363,915
R01 · FY2016 · AI · contact PI
Mtb regulators of essential and virulence-associated MmpLs$476,388
R56 · FY2015 · AI
Structure and mechanism of the AbgT-family transporters$364,361
R01 · FY2015 · AI · contact PI
Metal ion export in bacteria$269,696
R01 · FY2013 · GM · contact PI
Metal ion export in bacteria$279,726
R01 · FY2012 · GM · contact PI
Metal ion export in bacteria$279,964
R01 · FY2011 · GM · contact PI
Metal ion export in bacteria$283,023
R01 · FY2010 · GM · contact PI
Efflux pump mechanisms for drug recognition/extrusion$231,902
R01 · FY2009 · GM · contact PI
Efflux pump mechanisms for drug recognition/extrusion$232,859
R01 · FY2008 · GM · contact PI
Efflux pump mechanisms for drug recognition/extrusion$233,822
R01 · FY2007 · GM · contact PI
Efflux pump mechanisms for drug recognition/extrusion$242,216
R01 · FY2006 · GM · contact PI
Efflux pump mechanisms for drug recognition/extrusion$248,731
R01 · FY2005 · GM
STRUCTURAL INVESTIGATIONS OF THE ASPARTATE CHEMORECEPTOR$43,772
F32 · FY2001 · CA
STRUCTURAL INVESTIGATIONS OF THE ASPARTATE CHEMORECEPTOR$39,232
F32 · FY2000 · CA