Manolis Kellis

Massachusetts Institute Of Technology

$46,984,324

Attributed

$89,218,988

Total exposure

Grants

Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $12.1M · FY2007–25

$20M$15M$10M$5M$0

'07

'08

'09

'10

'11

'12

'13

'14

'15

'16

'17

'18

'19

'20

'21

'22

'23

'24

'25

Funding mix

By agency

NIH$89,218,988 · 26

By mechanism

R01$48,113,275 · 13

U01$20,246,891 · 4

RF1$6,919,543 · 2

RC2$4,086,417 · 1

UH3$3,475,569 · 1

UG3$2,484,900 · 1

Top collaborators

Most similar at Massachusetts Institute Of Technology

Same institution · by research overlap

Peter Karl Sorger$53,861,857
Richard O Hynes$17,553,047
Veronique Belzil$4,105,202
David K. Gifford$23,199,191

Others in their field

Top investigators on “Alzheimer&Apos”

Jose A Luchsinger · Columbia University Health Sciences$56,595,040
Eric M Reiman · Banner Health$48,982,487
Yadong Huang · J. David Gladstone Institutes$40,311,515
Lindsay A. Farrer · Boston University Medical Campus$34,189,802
David M Holtzman · Washington University$28,985,806
Michael W Weiner · Northern California Institute Res &Educ$28,197,224

Research focus

Alzheimer&AposGenesMapsCell TypeEnhancersCellsData SetEpigenomicsPathway InteractionsNucleic Acid Regulatory SequencesGeneticVariantMolecularLinkAffectInsightPhenotypeBaseDissectionGene ExpressionResourcesSamplingGene Expression ProfileBrain

Grant awards (87)

Single Cell Transcriptomic and Epigenomic Dissection of Opioid and Cocaine Responses in HIV$2,610,459

U01 · FY2025 · DA · contact PI

Identification of TDP-43 modifiers through single-cell transcriptional and epigenomic dissection of ALS and FTLD-MND$1,752,943

R01 · FY2025 · NS

Single-cell epigenomic and trancriptional dissection of sex-specific differences in Alzheimerâs Disease$1,068,252

R01 · FY2025 · AG · contact PI

Single-cell multi-region transcriptional and epigenomic dissection of VCID.$1,034,087

R01 · FY2025 · NS · contact PI

Single-cell multi-region dissection of AD-pathogen interactions for HSV-1 and CMV$727,847

R01 · FY2025 · AG · contact PI

Single-Cell Transcriptional and Epigenomic Dissection to Identify Therapeutic Targets for ALS and FTD$700,630

R01 · FY2025 · AG · contact PI

Single-Cell Dissection of Ensembles and Cell Types Mediating Opioid Action in the Rodent Brain$616,630

R01 · FY2025 · DA

Integration and Validation of Single-Cell Neuronal and Immune Molecular Responses in SUD and HIV$558,668

R01 · FY2025 · DA · contact PI

Single Cell Transcriptomic and Epigenomic Dissection of Opioid and Cocaine Responses in HIV$2,610,459

U01 · FY2024 · DA · contact PI

Identification of TDP-43 modifiers through single-cell transcriptional and epigenomic dissection of ALS and FTLD-MND$1,818,953

R01 · FY2024 · NS

Single-cell epigenomic and trancriptional dissection of sex-specific differences in Alzheimerâs Disease$1,135,203

R01 · FY2024 · AG · contact PI

Single-cell multi-region dissection of AD-pathogen interactions for HSV-1 and CMV$752,834

R01 · FY2024 · AG · contact PI

Single-Cell Transcriptional and Epigenomic Dissection to Identify Therapeutic Targets for ALS and FTD$725,002

R01 · FY2024 · AG · contact PI

Single-Cell Dissection of Ensembles and Cell Types Mediating Opioid Action in the Rodent Brain$616,630

R01 · FY2024 · DA

Single Cell Transcriptomic and Epigenomic Dissection of Opioid and Cocaine Responses in HIV$2,433,874

U01 · FY2023 · DA · contact PI

Identification of TDP-43 modifiers through single-cell transcriptional and epigenomic dissection of ALS and FTLD-MND$2,054,384

R01 · FY2023 · NS

Construction of an Integrated Immune - Vascular Brain - Chip as a Platform for the Study, Drug Screening, and Treatments of Alzheimer's Disease$1,158,523

UH3 · FY2023 · NS

Single-cell epigenomic and trancriptional dissection of sex-specific differences in Alzheimerâs Disease$1,080,026

R01 · FY2023 · AG · contact PI

Single-cell multi-region dissection of AD-pathogen interactions for HSV-1 and CMV$786,088

R01 · FY2023 · AG · contact PI

Investigating cell-type specific convergence of APOE and ABCA7 lipid dysregulation in Alzheimerâs disease$753,667

R56 · FY2023 · AG

Single-Cell Transcriptional and Epigenomic Dissection to Identify Therapeutic Targets for ALS and FTD$733,242

R01 · FY2023 · AG · contact PI

Single-Cell Dissection of Ensembles and Cell Types Mediating Opioid Action in the Rodent Brain$616,630

R01 · FY2023 · DA

Single-cell multi-region transcriptional and epigenomic dissection of VCID.$3,058,535

RF1 · FY2022 · NS · contact PI

Single Cell Transcriptomic and Epigenomic Dissection of Opioid and Cocaine Responses in HIV$2,447,914

U01 · FY2022 · DA · contact PI

Identification of TDP-43 modifiers through single-cell transcriptional and epigenomic dissection of ALS and FTLD-MND$1,662,271

R01 · FY2022 · NS

Elucidating the Molecular Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Disease$1,294,415

R01 · FY2022 · AG · contact PI

Construction of an Integrated Immune-Vascular Brain - Chip as a Platform for the Study, Drug Screening, and Treatments of Alzheimer's Disease$1,158,523

UH3 · FY2022 · NS

Single-cell epigenomic and trancriptional dissection of sex-specific differences in Alzheimerâs Disease$1,085,125

R01 · FY2022 · AG · contact PI

Single-Cell Transcriptional and Epigenomic Dissection to Identify Therapeutic Targets for ALS and FTD$741,221

R01 · FY2022 · AG · contact PI

Single-Cell Dissection of Ensembles and Cell Types Mediating Opioid Action in the Rodent Brain$616,630

R01 · FY2022 · DA

Single Cell Transcriptomic and Epigenomic Dissection of Opioid and Cocaine Responses in HIV$2,461,914

U01 · FY2021 · DA · contact PI

Identification of TDP-43 modifiers through single-cell transcriptional and epigenomic dissection of ALS and FTLD-MND$1,817,770

R01 · FY2021 · NS

Epigenomic, transcriptional and cellular dissection of Alzheimer's variants$1,552,886

R01 · FY2021 · AG · contact PI

Elucidating the Molecular Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Disease$1,294,990

R01 · FY2021 · AG · contact PI

Construction of an integrated immune - vascular brain - chip as a platform for the study, drug screening, and treatments of Alzheimer's disease$1,158,523

UH3 · FY2021 · NS

Single-cell epigenomic and trancriptional dissection of sex-specific differences in Alzheimerâs Disease$1,076,916

R01 · FY2021 · AG · contact PI

Single-Cell Transcriptional and Epigenomic Dissection to Identify Therapeutic Targets for ALS and FTD$757,149

R01 · FY2021 · AG · contact PI

Epigenomic, transcriptional and cellular dissection of Alzheimer's variants$1,578,214

R01 · FY2020 · AG · contact PI

Single-cell transcriptional and epigenomic dissection of Alzheimer's Disease and Related Dementias$1,345,399

U01 · FY2020 · NS · contact PI

Elucidating the Molecular Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Disease$1,295,549

R01 · FY2020 · AG · contact PI

Single-Cell Transcriptional and Epigenomic Dissection to Identify Therapeutic Targets for ALS and FTD$753,520

R56 · FY2020 · AG · contact PI

Network-based prediction and validation of causal schizophrenia genes and variants$398,193

R01 · FY2020 · MH · contact PI

Construction of an integrated immune - vascular brain - chip as a platform for the study, drug screening, and treatments of Alzheimer's disease$225,900

UG3 · FY2020 · NS

Construction of an integrated immune - vascular brain - chip as a platform for the study, drug screening, and treatments of Alzheimer's disease$2,259,000

UG3 · FY2019 · NS

Epigenomic, transcriptional and cellular dissection of Alzheimer's variants$1,610,182

R01 · FY2019 · AG · contact PI

Single-cell transcriptional and epigenomic dissection of Alzheimer's Disease and Related Dementias$1,345,399

U01 · FY2019 · NS · contact PI

Elucidating the Molecular Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Disease$1,296,090

R01 · FY2019 · AG · contact PI

Single Cell Transcriptional and Epigenomic Dissection of Schizophrenia and Bipoloar Disease$624,981

U01 · FY2019 · MH · contact PI

Network-based prediction and validation of causal schizophrenia genes and variants$398,936

R01 · FY2019 · MH · contact PI

Epigenomic, transcriptional and cellular dissection of Alzheimer's variants$1,642,247

R01 · FY2018 · AG · contact PI

Single-cell transcriptional and epigenomic dissection of Alzheimer's Disease and Related Dementias$1,348,579

U01 · FY2018 · NS · contact PI

Elucidating the Molecular Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Disease$1,308,813

R01 · FY2018 · AG · contact PI

Network-based prediction and validation of causal schizophrenia genes and variants$427,188

R01 · FY2018 · MH · contact PI

Epigenomic, transcriptional and cellular dissection of Alzheimer's variants$1,527,396

R01 · FY2017 · AG · contact PI

Interpreting non-coding variants using epigenomics, regulatory models, & validation experiments$546,251

R01 · FY2017 · HG · contact PI

Network-based prediction and validation of causal schizophrenia genes and variants$475,347

R01 · FY2017 · MH · contact PI

Comparative analysis and regulatory architecture of epigenomics datasets$284,959

R01 · FY2017 · GM · contact PI

Interpreting non-coding variants using epigenomics, regulatory models, & validati$162,708

R01 · FY2017 · HG · contact PI

Cell type specific epigenetic analysis to understand complex mechanisms underlying Alzheimer's disease phenotypes$3,861,008

RF1 · FY2016 · AG

Interpreting non-coding variants using epigenomics, regulatory models, & validati$812,809

R01 · FY2016 · HG · contact PI

Network-based prediction and validation of causal schizophrenia genes and variants$424,175

R01 · FY2016 · MH · contact PI

Comparative analysis and regulatory architecture of epigenomics datasets$284,106

R01 · FY2016 · GM · contact PI

Epigenomic variation atlas across human tissues and individuals in GTEx$100,000

U01 · FY2016 · HG · contact PI

Epigenomic variation atlas across human tissues and individuals in GTEx$941,793

U01 · FY2015 · HG · contact PI

Interpreting non-coding variants using epigenomics, regulatory models, & validati$811,770

R01 · FY2015 · HG · contact PI

Epigenomic variation atlas across human tissues and individuals in GTEx$450,000

U01 · FY2015 · HG · contact PI

Comparative analysis and regulatory architecture of epigenomics datasets$283,300

R01 · FY2015 · GM · contact PI

Regulatory Morif Discovery in the Human Genome Using Comparative Genomics$55,688

R01 · FY2015 · HG · contact PI

Epigenomic variation atlas across human tissues and individuals in GTEx$1,291,947

U01 · FY2014 · HG · contact PI

Regulatory Morif Discovery in the Human Genome Using Comparative Genomics$670,000

R01 · FY2014 · HG · contact PI

Regulatory Morif Discovery in the Human Genome Using Comparative Genomics$406,271

R01 · FY2014 · HG · contact PI

Epigenomic variation atlas across human tissues and individuals in GTEx$234,173

U01 · FY2014 · HG · contact PI

Regulatory Morif Discovery in the Human Genome Using Comparative Genomics$395,908

R01 · FY2013 · HG · contact PI

Regulatory Morif Discovery in the Human Genome Using Comparative Genomics$414,563

R01 · FY2012 · HG · contact PI

A Data Analysis Center for integration of fly and worm modENCODE datasets$1,296,550

RC2 · FY2011 · HG · contact PI

Integrative analysis of genomic and epigenomic datasets in multiple cell types$449,390

RC1 · FY2011 · HG · contact PI

Regulatory Morif Discovery in the Human Genome Using Comparative Genomics$306,571

R01 · FY2011 · HG · contact PI

A Data Analysis Center for integration of fly and worm modENCODE datasets$1,316,360

RC2 · FY2010 · HG · contact PI

Genome-wide chromatin modification targeting by endogenous small RNAs$996,415

RC1 · FY2010 · CA

Integrative analysis of genomic and epigenomic datasets in multiple cell types$468,161

RC1 · FY2010 · HG · contact PI

Regulatory Morif Discovery in the Human Genome Using Comparative Genomics$372,834

R01 · FY2010 · HG · contact PI

Regulatory Morif Discovery in the Human Genome Using Comparative Genomics$310,423

R01 · FY2010 · HG · contact PI

A Data Analysis Center for integration of fly and worm modENCODE datasets$1,473,507

RC2 · FY2009 · HG · contact PI

Integrative analysis of genomic and epigenomic datasets in multiple cell types$471,240

RC1 · FY2009 · HG · contact PI

Regulatory Morif Discovery in the Human Genome Using Comparative Genomics$311,149

R01 · FY2009 · HG · contact PI

Regulatory Morif Discovery in the Human Genome Using Comparative Genomics$310,352

R01 · FY2008 · HG · contact PI

Regulatory Morif Discovery in the Human Genome Using Comparative Genomics$313,861

R01 · FY2007 · HG · contact PI