← Leaderboards
Shilpa J Buch
University Of Kansas Medical Center
$35,602,348
Attributed
$58,495,657
Total exposure
31
Grants
26
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $5.9M · FY2005–25$10M$7.5M$5M$2.5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$66,132,117 · 32
By mechanism
R01$39,673,738 · 19
U01$15,678,766 · 2
P30$8,814,349 · 2
R21$1,224,880 · 3
P20$590,384 · 5
R03$150,000 · 1
Top collaborators
- Minglei Guo24 shared
- Howard S. Fox21 shared
- Guoku Hu11 shared
- Siddappa N Byrareddy10 shared
- Kee Jun Kim5 shared
- Udaykumar Ranga5 shared
- Nazira El-Hage4 shared
- Courtney V. Fletcher4 shared
Others in their field
Top investigators on “Brain”
- Douglas S. Hawkins · Children'S Hosp Of Philadelphia$157,315,120
- Michael W Weiner · Northern California Institute Res &Educ$149,959,854
- David A Bennett · Rush University Medical Center$148,375,056
- David Heimbrook · Leidos Biomedical Research, Inc.$145,442,397
- Walter John Curran · Thomas Jefferson University$114,442,832
- Hongkui Zeng · Allen Institute$113,960,965
Research focus
BrainCellsMediatingBaseHiv InfectionsMicrogliaIn VitroMolecularInfectionHiv-1In VivoAntiretroviral TherapyPathogenesisMacaca MulattaProteinsPharmaceutical PreparationsDrug AbuseMacacaMacrophageResponseFutureNeuronsAffectAstrocytes
Grant awards (127)
Single cell determinants of brain in the context of viral persistence in SIV/cART/cocaine non-human primates$2,467,417
U01 · FY2025 · DA
Uncovering HIV/opioid effects in the brain at the single cell level: transcription, chromatin accessibility, and reservoir analysis in the SIV/cART/morphine/rhesus monkey model$929,071
U01 · FY2025 · DA
Title: Pharmacokinetic, pharmacodynamic , and toxicological interactions among Opioids and Cabotegravir$694,456
R01 · FY2025 · DA
Molecular interplay of HIV Tat, cocaine, and cART in microglial pyroptosis: Role of NLRP3 inflammasome$490,172
R01 · FY2025 · DA · contact PI
HIV Tat and Opiate-mediated aberrations in glial-neuronal crosstalk: Implications for the role of extracellular RNA in HAND$472,930
R01 · FY2025 · DA · contact PI
Single cell determinants of brain in the context of viral persistence in SIV/cART/cocaine non-human primates$2,473,493
U01 · FY2024 · DA
Uncovering HIV/opioid effects in the brain at the single cell level: transcription, chromatin accessibility, and reservoir analysis in the SIV/cART/morphine/rhesus monkey model$1,579,167
U01 · FY2024 · DA
HIV Tat and Opiate-mediated aberrations in glial-neuronal crosstalk: Implications for the role of extracellular RNA in HAND$469,340
R01 · FY2024 · DA · contact PI
Title: Pharmacokinetic, pharmacodynamic , and toxicological interactions among Opioids and Cabotegravir$356,454
R01 · FY2024 · DA
Single cell determinants of brain in the context of viral persistence in SIV/cART/cocaine non-human primates$2,494,069
U01 · FY2023 · DA
Uncovering HIV/opioid effects in the brain at the single cell level: transcription, chromatin accessibility, and reservoir analysis in the SIV/cART/morphine/rhesus monkey model$2,099,091
U01 · FY2023 · DA
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome$514,688
R01 · FY2023 · DA · contact PI
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome$383,750
R01 · FY2023 · DA · contact PI
Title: Pharmacokinetic, pharmacodynamic , and toxicological interactions among Opioids and Cabotegravir$365,335
R01 · FY2023 · DA
Uncovering HIV/opioid effects in the brain at the single cell level: transcription, chromatin accessibility, and reservoir analysis in the SIV/cART/morphine/rhesus monkey model$2,093,258
U01 · FY2022 · DA
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome$514,688
R01 · FY2022 · DA · contact PI
Title: Pharmacokinetic, pharmacodynamic , and toxicological interactions among Opioids and Cabotegravir$374,030
R01 · FY2022 · DA
Mechanisms underlying dysregulated neuroimmune signaling and neuronal dysfunction in HIV (+) individuals with cART and cocaine$362,188
R01 · FY2022 · DA · contact PI
Uncovering HIV/opioid effects in the brain at the single cell level: transcription, chromatin accessibility, and reservoir analysis in the SIV/cART/morphine/rhesus monkey model$125,849
U01 · FY2022 · DA
Chronic HIV Infection and Aging in NeuroAIDS (CHAIN) Center$1,525,860
P30 · FY2021 · MH
Uncovering HIV/opioid effects in the brain at the single cell level: transcription, chromatin accessibility, and reservoir analysis in the SIV/cART/morphine/rhesus monkey model$1,417,351
U01 · FY2021 · DA
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome$476,259
R01 · FY2021 · DA · contact PI
HIV-1 mediated synaptodendritic injury and microglial activation: Role of extracellular vesicle miRNAs$386,785
R01 · FY2021 · MH · contact PI
Combinatorial effects of HIV, cART, & morphine on neuroinflammation: implications for HAND$381,250
R01 · FY2021 · DA · contact PI
Mechanisms underlying dysregulated neuroimmune signaling and neuronal dysfunction in HIV (+) individuals with cART and cocaine$362,188
R01 · FY2021 · DA · contact PI
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome$15,211
R01 · FY2021 · DA · contact PI
Chronic HIV Infection and Aging in NeuroAIDS (CHAIN) Center$1,512,315
P30 · FY2020 · MH · contact PI
The brain as a SIV reservoir under suppressive cART potentiation by drugs of abuse$752,188
R01 · FY2020 · DA
The combinatorial effects of Opiates and the emerging promoter-variant strains of HIV-1 subtype C on HIV neuropathogensis and latency$718,779
R01 · FY2020 · DA · contact PI
HIV-1 mediated synaptodendritic injury and microglial activation: Role of extracellular vesicle miRNAs$386,785
R01 · FY2020 · MH · contact PI
Combinatorial effects of HIV, cART, & morphine on neuroinflammation: implications for HAND$381,250
R01 · FY2020 · DA · contact PI
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome$377,439
R01 · FY2020 · DA · contact PI
HIV Tat & cocaine-mediated alterations in microglial migration & activation involve epigenetic reulation of miRNAs$376,250
R01 · FY2020 · DA · contact PI
Mechanisms underlying dysregulated neuroimmune signaling and neuronal dysfunction in HIV (+) individuals with cART and cocaine$362,188
R01 · FY2020 · DA · contact PI
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome$107,789
R01 · FY2020 · DA · contact PI
Chronic HIV Infection and Aging in NeuroAIDS (CHAIN) Center$1,525,860
P30 · FY2019 · MH · contact PI
The combinatorial effects of Opiates and the emerging promoter-variant strains of HIV-1 subtype C on HIV neuropathogensis and latency$757,800
R01 · FY2019 · DA · contact PI
The brain as a SIV reservoir under suppressive cART potentiation by drugs of abuse$752,188
R01 · FY2019 · DA
HIV Tat & Morphine induce mircroglial migration & activation via release of miR-9 & 138$500,413
R01 · FY2019 · DA · contact PI
PDGF-CC Mediated Reversal of Synaptodendritic Injury in HAND$405,021
R01 · FY2019 · MH · contact PI
HIV-1 mediated synaptodendritic injury and microglial activation: Role of extracellular vesicle miRNAs$386,785
R01 · FY2019 · MH · contact PI
Combinatorial effects of HIV, cART, & morphine on neuroinflammation: implications for HAND$381,250
R01 · FY2019 · DA
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome$377,438
R01 · FY2019 · DA · contact PI
HIV Tat & cocaine-mediated alterations in microglial migration & activation involve epigenetic reulation of miRNAs$376,250
R01 · FY2019 · DA · contact PI
Mechanisms underlying dysregulated neuroimmune signaling and neuronal dysfunction in HIV (+) individuals with cART and cocaine$362,188
R01 · FY2019 · DA
Chronic HIV Infection and Aging in NeuroAIDS (CHAIN) Center$1,521,315
P30 · FY2018 · MH · contact PI
The combinatorial effects of Opiates and the emerging promoter-variant strains of HIV-1 subtype C on HIV neuropathogensis and latency$830,071
R01 · FY2018 · DA · contact PI
The brain as a SIV reservoir under suppressive cART potentiation by drugs of abuse$752,188
R01 · FY2018 · DA
HIV Tat & Morphine induce mircroglial migration & activation via release of miR-9 & 138$500,413
R01 · FY2018 · DA · contact PI
PDGF-CC Mediated Reversal of Synaptodendritic Injury in HAND$478,969
R01 · FY2018 · MH · contact PI
HIV-1 mediated synaptodendritic injury and microglial activation: Role of extracellular vesicle miRNAs$455,408
R01 · FY2018 · MH · contact PI
Combinatorial effects of HIV, cART, & morphine on neuroinflammation: implications for HAND$381,042
R01 · FY2018 · DA
HIV Tat & cocaine-mediated alterations in microglial migration & activation involve epigenetic reulation of miRNAs$376,250
R01 · FY2018 · DA · contact PI
Mechanisms underlying dysregulated neuroimmune signaling and neuronal dysfunction in HIV (+) individuals with cART and cocaine$362,188
R01 · FY2018 · DA
Chronic HIV Infection and Aging in NeuroAIDS (CHAIN) Center$1,551,110
P30 · FY2017 · MH · contact PI
The combinatorial effects of Opiates and the emerging promoter-variant strains of HIV-1 subtype C on HIV neuropathogensis and latency$838,842
R01 · FY2017 · DA · contact PI
The brain as a SIV reservoir under suppressive cART potentiation by drugs of abuse$752,188
R01 · FY2017 · DA
Opiate induced SIV-Neuropathogenesis: Role of miRNA-29b in the Periphery-CNS Cro$545,735
R01 · FY2017 · DA · contact PI
HIV Tat & Morphine induce mircroglial migration & activation via release of miR-9 & 138$500,413
R01 · FY2017 · DA · contact PI
HIV-1 mediated synaptodendritic injury and microglial activation: Role of extracellular vesicle miRNAs$476,063
R01 · FY2017 · MH · contact PI
PDGF-CC Mediated Reversal of Synaptodendritic Injury in HAND$459,153
R01 · FY2017 · MH · contact PI
Combinatorial effects of HIV, cART, & morphine on neuroinflammation: implications for HAND$378,750
R01 · FY2017 · DA
HIV Tat & cocaine-mediated alterations in microglial migration & activation involve epigenetic reulation of miRNAs$376,250
R01 · FY2017 · DA · contact PI
HIV Tat & cocaine-mediated alterations in microglial migration & activation involve epigenetic reulation of miRNAs$8,467
R01 · FY2017 · DA · contact PI
The brain as a SIV reservoir under suppressive cART potentiation by drugs of abuse$752,188
R01 · FY2016 · DA
The combinatorial effects of Opiates and the emerging promoter-variant strains of HIV-1 subtype C on HIV neuropathogensis and latency$744,839
R01 · FY2016 · DA · contact PI
HIV Tat & Morphine induce mircroglial migration & activation via release of miR-9 & 138$495,408
R01 · FY2016 · DA · contact PI
PDGF-CC Mediated Reversal of Synaptodendritic Injury in HAND$453,202
R01 · FY2016 · MH · contact PI
Opiate induced SIV-Neuropathogenesis: Role of miRNA-29b in the Periphery-CNS Cro$434,810
R01 · FY2016 · DA · contact PI
HIV Tat & cocaine-mediated alterations in microglial migration & activation involve epigenetic reulation of miRNAs$376,250
R01 · FY2016 · DA · contact PI
HIV Tat & Morphine induce mircroglial migration & activation via release of miR-9 & 138$500,413
R01 · FY2015 · DA · contact PI
PDGF-CC Mediated Reversal of Synaptodendritic Injury in HAND$477,659
R01 · FY2015 · MH · contact PI
Opiate induced SIV-Neuropathogenesis: Role of miRNA-29b in the Periphery-CNS Cro$425,301
R01 · FY2015 · DA · contact PI
HIV Tat & Cocaine-Mediated induction of Astrogliosis: Role of ER Stress in HAND$370,606
R01 · FY2015 · DA · contact PI
PDGF-BB Reverses Impaired Neurogenesis Mediated by Tat and Cocaine$329,113
R01 · FY2015 · DA · contact PI
Cell/Tissue/Animal Core (Page 182)$219,398
P30 · FY2015 · MH · contact PI
Opiate induced SIV-Neuropathogenesis: Role of miRNA-29b in the Periphery-CNS Cro$445,688
R01 · FY2014 · DA · contact PI
HIV Tat & Cocaine-Mediated induction of Astrogliosis: Role of ER Stress in HAND$376,250
R01 · FY2014 · DA · contact PI
PDGF-BB Reverses Impaired Neurogenesis Mediated by Tat and Cocaine$334,125
R01 · FY2014 · DA · contact PI
Cell/Tissue/Animal Core (Page 182)$222,137
P30 · FY2014 · MH · contact PI
Opiate induced SIV-Neuropathogenesis: Role of miRNA-29b in the Periphery-CNS Cro$436,367
R01 · FY2013 · DA · contact PI
HIV Tat & Cocaine-Mediated induction of Astrogliosis: Role of ER Stress in HAND$376,250
R01 · FY2013 · DA · contact PI
Cocaine & HIV: Role of PDGF/PDGF-Receptor Axis in Blood Brain Barrier Disruption$345,469
R01 · FY2013 · DA · contact PI
PDGF-BB Reverses Impaired Neurogenesis Mediated by Tat and Cocaine$320,760
R01 · FY2013 · DA · contact PI
Cell/Tissue/Animal Core (Page 182)$224,858
P30 · FY2013 · MH · contact PI
Cocaine & HIV: Role of PDGF/PDGF-Receptor Axis in Blood Brain Barrier Disruption$365,755
R01 · FY2012 · DA · contact PI
Mechanism and Therapy of HIV Encephalitis$340,641
R01 · FY2012 · MH · contact PI
PDGF-BB Reverses Impaired Neurogenesis Mediated by Tat and Cocaine$334,125
R01 · FY2012 · DA · contact PI
Cell/Tissue/Animal Core (Page 182)$262,646
P30 · FY2012 · MH · contact PI
Molecular Mechanisms & Therapy for Cocaine Abuse in HAND$200,436
R21 · FY2012 · DA · contact PI
Cell/Tissue/Animal Core (Page 182)$11,250
P30 · FY2012 · MH · contact PI
Morphine and the Neuropathogenesis of SIV in Macaques$427,818
R01 · FY2011 · DA · contact PI
Cocaine & HIV: Role of PDGF/PDGF-Receptor Axis in Blood Brain Barrier Disruption$371,789
R01 · FY2011 · DA · contact PI
Mechanism and Therapy of HIV Encephalitis$347,454
R01 · FY2011 · MH · contact PI
Cell/Tissue/Animal Core (Page 182)$237,600
P30 · FY2011 · MH · contact PI
Molecular Mechanisms & Therapy for Cocaine Abuse in HAND$202,824
R21 · FY2011 · DA · contact PI
Morphine and the Neuropathogenesis of SIV in Macaques$732,432
R01 · FY2010 · DA · contact PI
Cocaine & HIV: Role of PDGF/PDGF-Receptor Axis in Blood Brain Barrier Disruption$373,820
R01 · FY2010 · DA · contact PI
Mechanism and Therapy of HIV Encephalitis$350,963
R01 · FY2010 · MH · contact PI
HIV-Encephalitis and Cocaine Abuse: Mechanism of Synergy and Therapy$279,793
R01 · FY2010 · DA · contact PI
PLGA/Antisense IL-10: Gene Therapy for Cocaine Abusers with HAD$221,565
R21 · FY2010 · DA · contact PI
Morphine and the Neuropathogenesis of SIV in Macaques$702,275
R01 · FY2009 · DA · contact PI
Cocaine & HIV: Role of PDGF/PDGF-Receptor Axis in Blood Brain Barrier Disruption$384,712
R01 · FY2009 · DA · contact PI
Mechanism and Therapy of HIV Encephalitis$314,213
R01 · FY2009 · MH · contact PI
HIV-Encephalitis and Cocaine Abuse: Mechanism of Synergy and Therapy$282,619
R01 · FY2009 · DA · contact PI
PLGA/Antisense IL-10: Gene Therapy for Cocaine Abusers with HAD$173,732
R21 · FY2009 · DA · contact PI
LUMINEX CORE$83,784
P20 · FY2009 · RR · contact PI
PLGA/Antisense IL-10: Gene Therapy for Cocaine Abusers with HAD$27,255
R21 · FY2009 · DA · contact PI
Morphine and the Neuropathogenesis of SIV in Macaques$449,154
R01 · FY2008 · DA · contact PI
Mechanism and Therapy of HIV Encephalitis$330,750
R01 · FY2008 · MH · contact PI
HIV-Encephalitis and Cocaine Abuse: Mechanism of Synergy and Therapy$279,765
R01 · FY2008 · DA · contact PI
LUMINEX CORE$77,765
P20 · FY2008 · RR · contact PI
Morphine and the Neuropathogenesis of SIV in Macaques$531,418
R01 · FY2007 · DA · contact PI
HIV-Encephalitis and Cocaine Abuse: Mechanism of Synergy and Therapy$285,474
R01 · FY2007 · DA · contact PI
LUMINEX CORE$74,791
P20 · FY2007 · RR · contact PI
HIV-Encephalitis and Cocaine Abuse: Mechanism of Synergy and Therapy$23,000
R01 · FY2007 · DA · contact PI
HIV-Encephalitis and Cocaine Abuse: Mechanism of Synergy and Therapy$294,000
R01 · FY2006 · DA · contact PI
Mechanism and Therapy of SHIV Encephalitis in Macaques$251,205
R01 · FY2006 · MH · contact PI
IMMUNOGENICITY OF AN HIV DNA VACCINE$245,279
P20 · FY2006 · RR · contact PI
Development of Neuronal gene therapy for HIV-dementia$215,318
R21 · FY2006 · MH · contact PI
LUMINEX CORE: AIDS$108,765
P20 · FY2006 · RR · contact PI
Mechanism and Therapy of SHIV Encephalitis in Macaques$257,250
R01 · FY2005 · MH
Development of Neuronal gene therapy for HIV-dementia$183,750
R21 · FY2005 · MH
Mechanism and Therapy of SHIV Encephalitis in Macaques$257,250
R01 · FY2004 · MH
Mechanism and Therapy of SHIV Encephalitis in Macaques$257,250
R01 · FY2003 · MH
DEVELOPMENT OF GENE THERAPY FOR LENTIVIRAL ENCEPHALITIS$75,000
R03 · FY2002 · MH
DEVELOPMENT OF GENE THERAPY FOR LENTIVIRAL ENCEPHALITIS$75,000
R03 · FY2001 · MH