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Minglei Guo

University Of Nebraska Medical Center

$7,203,802
Attributed
$13,525,031
Total exposure
10
Grants
6
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $1.6M · FY201625
$2M$1.5M$1M$500K$0
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$13,525,031 · 10

By mechanism

R01$11,951,156 · 7
R21$853,875 · 2
R34$720,000 · 1

Top collaborators

Most similar at University Of Nebraska Medical Center

Same institution · by research overlap

Others in their field

Top investigators on “Proteins

Research focus

ProteinsBrainMicrogliaPrevalenceMediatingIn VivoSignal TransductionIn VitroAntiretroviral TherapyCocaineDrug AbuseGenetic TranscriptionNeuroinflammationTrans-ActivatorsPathway InteractionsHiv-Associated Neurocognitive DisorderCocaine AbuseInflammasomeAffectQuality Of LifeComorbidityCellsDrug Of AbuseBase

Grant awards (38)

HIV and cocaine mediated lipid dysregulation in microglia: Immunometabolism mechanisms underlying NeuroHIV$563,742
R01 · FY2025 · DA · contact PI
Role of the NLRP3 Inflammasome in Mediating Microglial Activation and Development of Neuropsychiatric Symptoms Induced by HIV, Antiretrovirals and Cocaine$375,999
R01 · FY2025 · DA · contact PI
Effects of social isolation and loneliness during early life on neurocognitive development and addiction$360,000
R34 · FY2025 · DA
Mg-based therapy for mitigating HAND and neuropsychiatric symptoms in the condition of chronic HIV infection$440,000
R21 · FY2024 · AG · contact PI
Role of the NLRP3 Inflammasome in Mediating Microglial Activation and Development of Neuropsychiatric Symptoms Induced by HIV, Antiretrovirals and Cocaine$375,971
R01 · FY2024 · DA · contact PI
Effects of social isolation and loneliness during early life on neurocognitive development and addiction$360,000
R34 · FY2024 · DA
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome$514,688
R01 · FY2023 · DA
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome$383,750
R01 · FY2023 · DA
Role of the NLRP3 Inflammasome in Mediating Microglial Activation and Development of Neuropsychiatric Symptoms Induced by HIV, Antiretrovirals and Cocaine$375,942
R01 · FY2023 · DA · contact PI
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome$514,688
R01 · FY2022 · DA
Role of the NLRP3 Inflammasome in Mediating Microglial Activation and Development of Neuropsychiatric Symptoms Induced by HIV, Antiretrovirals and Cocaine$379,644
R01 · FY2022 · DA · contact PI
Role of the NLRP3 Inflammasome in Mediating Microglial Activation and Development of Neuropsychiatric Symptoms Induced by HIV, Antiretrovirals and Cocaine$375,000
R01 · FY2022 · DA · contact PI
Mechanisms underlying dysregulated neuroimmune signaling and neuronal dysfunction in HIV (+) individuals with cART and cocaine$362,188
R01 · FY2022 · DA
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome$476,259
R01 · FY2021 · DA
Role of the NLRP3 Inflammasome in Mediating Microglial Activation and Development of Neuropsychiatric Symptoms Induced by HIV, Antiretrovirals and Cocaine$384,660
R01 · FY2021 · DA · contact PI
Combinatorial effects of HIV, cART, & morphine on neuroinflammation: implications for HAND$381,250
R01 · FY2021 · DA
Mechanisms underlying dysregulated neuroimmune signaling and neuronal dysfunction in HIV (+) individuals with cART and cocaine$362,188
R01 · FY2021 · DA
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome$15,211
R01 · FY2021 · DA
Combinatorial effects of HIV, cART, & morphine on neuroinflammation: implications for HAND$381,250
R01 · FY2020 · DA
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome$377,439
R01 · FY2020 · DA
HIV Tat & cocaine-mediated alterations in microglial migration & activation involve epigenetic reulation of miRNAs$376,250
R01 · FY2020 · DA
Mechanisms underlying dysregulated neuroimmune signaling and neuronal dysfunction in HIV (+) individuals with cART and cocaine$362,188
R01 · FY2020 · DA
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome$107,789
R01 · FY2020 · DA
Combinatorial effects of HIV, cART, & morphine on neuroinflammation: implications for HAND$381,250
R01 · FY2019 · DA · contact PI
Molecular mechanisms underlying HIV & Cocaine-mediated microglial activation: Targeting NLRP3 inflammasome$377,438
R01 · FY2019 · DA
HIV Tat & cocaine-mediated alterations in microglial migration & activation involve epigenetic reulation of miRNAs$376,250
R01 · FY2019 · DA
Mechanisms underlying dysregulated neuroimmune signaling and neuronal dysfunction in HIV (+) individuals with cART and cocaine$362,188
R01 · FY2019 · DA · contact PI
Combinatorial effects of HIV, cART, & morphine on neuroinflammation: implications for HAND$381,042
R01 · FY2018 · DA · contact PI
HIV Tat & cocaine-mediated alterations in microglial migration & activation involve epigenetic reulation of miRNAs$376,250
R01 · FY2018 · DA
Mechanisms underlying dysregulated neuroimmune signaling and neuronal dysfunction in HIV (+) individuals with cART and cocaine$362,188
R01 · FY2018 · DA · contact PI
Exosome-mediated anti-microRNA delivery into the CNS: A Novel Threpautic for HAND in opiate users$188,125
R21 · FY2018 · DA
Combinatorial effects of HIV, cART, & morphine on neuroinflammation: implications for HAND$378,750
R01 · FY2017 · DA · contact PI
HIV Tat & Cocaine-Mediated induction of Astrogliosis: Role of ER Stress in HAND$376,250
R01 · FY2017 · DA · contact PI
HIV Tat & cocaine-mediated alterations in microglial migration & activation involve epigenetic reulation of miRNAs$376,250
R01 · FY2017 · DA
Exosome-mediated anti-microRNA delivery into the CNS: A Novel Threpautic for HAND in opiate users$225,750
R21 · FY2017 · DA
HIV Tat & cocaine-mediated alterations in microglial migration & activation involve epigenetic reulation of miRNAs$8,467
R01 · FY2017 · DA
HIV Tat & cocaine-mediated alterations in microglial migration & activation involve epigenetic reulation of miRNAs$376,250
R01 · FY2016 · DA
HIV Tat & Cocaine-Mediated induction of Astrogliosis: Role of ER Stress in HAND$372,487
R01 · FY2016 · DA · contact PI