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Gregory R Hook

Activesite Biotech

$7,385,594
Attributed
$7,385,594
Total exposure
8
Grants
6
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants. They are the sole PI on all grants (the two match).

Funding over time

peak $1.4M · FY200519
$2M$1.5M$1M$500K$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19

Funding mix

By agency

NIH$7,385,594 · 8

By mechanism

R44$6,023,701 · 4
R21$638,543 · 2
R41$623,350 · 1
R43$100,000 · 1

Top collaborators

No co-investigators on record.

Others in their field

Top investigators on “Alzheimer&Apos

Research focus

Alzheimer&AposBrainInhibitor/AntagonistPeptide HydrolasesCathepsins BPharmaceutical PreparationsAnimalsGrantIn VivoMouse ModelS DiseaseAnimal ModelChromaffin CellsCysteine ProteaseCleaved CellCaviaBehaviorDosePathway InteractionsMemory ImpairmentAmyloid PeptideAmyloid Beta-Protein PrecursorCysteine Proteinase InhibitorsPathology

Grant awards (22)

Development of a commercialization plan for traumatic brain injury therapeutics$55,000
R41 · FY2019 · NS · contact PI
Administrative Supplement to restore fee funds$36,172
R41 · FY2019 · NS · contact PI
Cathepsin B inhibitor Drug Development for Traumatic Brain Injury$532,178
R41 · FY2018 · NS · contact PI
Development of E64d for Alzheimer's disease$58,511
R44 · FY2011 · AG · contact PI
Development of protease inhibitor drugs to treat Alzheimer's disease$717,300
R44 · FY2010 · AG · contact PI
Development of E64d for Alzheimer's disease$581,324
R44 · FY2010 · AG · contact PI
Prodrugs to treat Alzheimer's disease$101,570
R21 · FY2010 · AG · contact PI
Development of E64d for Alzheimer's disease$567,196
R44 · FY2009 · AG · contact PI
Development of protease inhibitor drugs to treat Alzheimer's disease$427,472
R44 · FY2009 · AG · contact PI
Prodrugs to treat Alzheimer's disease$215,306
R21 · FY2009 · AG · contact PI
Development of protease inhibitor drugs to treat Alzheimer's disease$195,997
R44 · FY2009 · AG · contact PI
Development of E64d for Alzheimer's disease$115,137
R44 · FY2008 · AG · contact PI
Development of protease inhibitor drugs to treat Alzheimer's disease$95,089
R44 · FY2008 · AG · contact PI
Inhibitors of beta-Amyloid Production in Alzheimer's$158,467
R21 · FY2007 · AG · contact PI
Gamma Secretase Assays to Discover Drugs for Alzheimer's$808,397
R44 · FY2006 · AG · contact PI
Inhibitors of beta-Amyloid Production in Alzheimer's$163,200
R21 · FY2006 · AG · contact PI
Gamma Secretase Assays to Discover Drugs for Alzheimer's$763,308
R44 · FY2005 · AG
Beta-Secretase Assays to Discover Drugs for Alzheimer's$378,993
R44 · FY2004 · AG
Beta-Secretase Assays to Discover Drugs for Alzheimer's$598,044
R44 · FY2003 · AG
Beta-Secretase Assays to Discover Drugs for Alzheimer's$401,171
R44 · FY2002 · AG
Beta-Secretase Assays to Discover Drugs for Alzheimer's$315,762
R44 · FY2002 · AG
GAMMA SECRETASE ASSAYS FOR DRUG DISCOVERY IN ALZHEIMER'S$100,000
R43 · FY2000 · AG