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David R Borchelt

University Of Florida

$17,132,004
Attributed
$26,649,263
Total exposure
24
Grants
14
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $4.2M · FY200525
$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$26,649,263 · 24

By mechanism

R01$13,027,188 · 7
P01$2,935,310 · 3
R21$2,857,537 · 7
RF1$2,610,464 · 1
R33$1,817,356 · 1
P50$1,429,442 · 2

Most similar at University Of Florida

Same institution · by research overlap

Others in their field

Top investigators on “Alzheimer&Apos

Research focus

Alzheimer&AposPathologyProteinsMouse ModelPathologicMutantLinkTransgenic MiceS DiseaseBrainAnimalsBaseMutationNeurofibrillary TanglesAmyloidPathogenesisTissuesAffectMediatingPathway InteractionsAppearanceInsightLaboratoriesDeposition

Grant awards (73)

Deciphering tau phosphorylation and Abeta/tau strain interactions in Alzheimer’s pathogenesis$481,006
R01 · FY2025 · AG
Deciphering tau phosphorylation and Abeta/tau strain interactions in Alzheimer’s pathogenesis$497,937
R01 · FY2024 · AG
Modeling the progression of SOD1-linked motor neuron disease$395,361
R01 · FY2024 · NS · contact PI
Deciphering tau phosphorylation and Abeta/tau strain interactions in Alzheimer’s pathogenesis$490,314
R01 · FY2023 · AG
Modeling the progression of SOD1-linked motor neuron disease$415,095
R01 · FY2023 · NS · contact PI
Deciphering tau phosphorylation and Abeta/tau strain interactions in Alzheimer’s pathogenesis$455,239
R01 · FY2022 · AG
Modeling the progression of SOD1-linked motor neuron disease$425,235
R01 · FY2022 · NS · contact PI
Prion and non-prion induction mechanisms of alpha-synuclein pathology$379,532
R01 · FY2022 · NS
Developing new conditional models to study tauopathy, amyloidosis, and their interaction$1,817,356
R33 · FY2021 · NS
Prion and non-prion induction mechanisms of alpha-synuclein pathology$379,614
R01 · FY2021 · NS
Prion and non-prion induction mechanisms of alpha-synuclein pathology$379,691
R01 · FY2020 · NS
Developing new conditional models to study tauopathy, amyloidosis, and their interaction$1,200,370
R61 · FY2019 · NS
Prion and non-prion induction mechanisms of alpha-synuclein pathology$379,766
R01 · FY2019 · NS
Modeling the progression of SOD1-linked motor neuron disease$328,125
R01 · FY2019 · NS · contact PI
Proteostasis and secondary proteinopathy in AD and FTD$307,500
R01 · FY2019 · AG · contact PI
Project 3$156,423
P50 · FY2019 · AG · contact PI
APOE as a modifier of prion-like spread in dementia$2,610,464
RF1 · FY2018 · AG · contact PI
Prion and non-prion induction mechanisms of alpha-synuclein pathology$379,836
R01 · FY2018 · NS
Modeling the progression of SOD1-linked motor neuron disease$328,125
R01 · FY2018 · NS · contact PI
Proteostasis and secondary proteinopathy in AD and FTD$307,500
R01 · FY2018 · AG · contact PI
Is there a form of benign brain amyloidosis in aging?$228,750
R21 · FY2018 · AG · contact PI
New Drug Discovery Paradigms for Synucleinopathies$201,111
R21 · FY2018 · AG
Project 3$173,640
P50 · FY2018 · AG · contact PI
APOE as a modifier of prion-like spread in dementia$689,846
R56 · FY2017 · AG · contact PI
Modeling the progression of SOD1-linked motor neuron disease$328,125
R01 · FY2017 · NS · contact PI
Proteostasis and secondary proteinopathy in AD and FTD$307,500
R01 · FY2017 · AG · contact PI
New Drug Discovery Paradigms for Synucleinopathies$258,676
R21 · FY2017 · AG
Is there a form of benign brain amyloidosis in aging?$190,625
R21 · FY2017 · AG · contact PI
Project 3$177,209
P50 · FY2017 · AG · contact PI
Modeling the progression of SOD1-linked motor neuron disease$328,125
R01 · FY2016 · NS · contact PI
Proteostasis and secondary proteinopathy in AD and FTD$307,500
R01 · FY2016 · AG · contact PI
Seeded transmission of SOD1 misfolding$187,500
R21 · FY2016 · NS · contact PI
Project 3$178,923
P50 · FY2016 · AG · contact PI
Modeling the progression of SOD1-linked motor neuron disease$328,125
R01 · FY2015 · NS · contact PI
Proteostasis and secondary proteinopathy in AD and FTD$307,500
R01 · FY2015 · AG · contact PI
Seeded transmission of SOD1 misfolding$225,000
R21 · FY2015 · NS · contact PI
Seeded models of AD pathology$181,875
R21 · FY2015 · AG · contact PI
Project 3$178,923
P50 · FY2015 · AG · contact PI
Project 3$237,615
P01 · FY2014 · NS · contact PI
Seeded models of AD pathology$224,750
R21 · FY2014 · AG · contact PI
Proteostasis in Neurodegenerative Disease$187,500
R21 · FY2014 · NS · contact PI
Project 3$238,942
P01 · FY2013 · NS · contact PI
Proteostasis in Neurodegenerative Disease$223,500
R21 · FY2013 · NS · contact PI
Repair and Regeneration in Alzheimer's Disease$424,668
R01 · FY2012 · NS · contact PI
Project 3$250,329
P01 · FY2012 · NS · contact PI
New Models to Assay Gene Silencing Therapies$183,125
R21 · FY2012 · NS · contact PI
Repair and Regeneration in Alzheimer's Disease$439,261
R01 · FY2011 · NS · contact PI
New Models to Assay Gene Silencing Therapies$219,750
R21 · FY2011 · NS · contact PI
Project 3$207,020
P01 · FY2011 · NS · contact PI
Repair and Regeneration in Alzheimer's Disease$449,988
R01 · FY2010 · NS · contact PI
Project 3$228,037
P01 · FY2010 · NS · contact PI
Repair and Regeneration in Alzheimer's Disease$466,474
R01 · FY2009 · NS · contact PI
Testing Hypotheses by Site Directed Mutagenesis of SOD1$368,477
P01 · FY2009 · NS · contact PI
Testing Hypotheses by Site Directed Mutagenesis of SOD1$358,786
P01 · FY2008 · NS · contact PI
Testing Hypotheses by Site Directed Mutagenesis of SOD1$372,574
P01 · FY2007 · NS · contact PI
Protein Misfolding in Neurodegeneration$322,651
R01 · FY2007 · NS · contact PI
Repair and Regeneration in Alzheimer's Disease$321,226
R01 · FY2007 · NS · contact PI
Repair and Regeneration in Alzheimer's Disease$369,209
R01 · FY2006 · NS · contact PI
Testing Hypotheses by Site Directed Mutagenesis of SOD1$348,994
P01 · FY2006 · NS · contact PI
Protein Misfolding in Neurodegeneration$332,288
R01 · FY2006 · NS · contact PI
Repair and Regeneration in Alzheimer's Disease$372,273
R01 · FY2005 · NS
Protein Misfolding in Neurodegeneration$340,284
R01 · FY2005 · NS
Testing Hypotheses by Site Directed Mutagenesis of SOD1$324,536
P01 · FY2005 · NS
Protein Ubiquitination in Cell Models of Disease$181,875
R21 · FY2005 · AG
Repair and Regeneration in Alzheimer's Disease$363,997
R01 · FY2004 · NS
Protein Misfolding in Neurodegeneration$340,284
R01 · FY2004 · NS
Protein Ubiquitination in Cell Models of Disease$163,500
R21 · FY2004 · AG
Assessing memory in mouse models of Alzhiemer's disease$158,272
P50 · FY2002 · AG
In vivo assessment of proteasome function$81,750
R03 · FY2002 · AG
Assessing memory in mouse models of Alzhiemer's disease$158,272
P50 · FY2001 · AG
HUNTINGTON'S DISEASE MODELS$0
P01 · FY2001 · NS
COPPER AND MOTOR NEURON DEGENERATION$247,834
R01 · FY2000 · NS
Assessing memory in mouse models of Alzhiemer's disease$247,780
P50 · FY2000 · AG