← Leaderboards
Michael D Koob
University Of Minnesota Twin Cities
$10,733,200
Attributed
$23,118,640
Total exposure
14
Grants
7
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $4.9M · FY2005–25$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$23,118,640 · 14
By mechanism
R01$12,383,637 · 5
RF1$4,147,326 · 1
R33$2,280,898 · 1
R61$1,507,494 · 1
R56$1,329,167 · 1
R21$1,168,262 · 3
Top collaborators
- Timothy J Ebner6 shared
- Dezhi Liao6 shared
- Bruce T Lamb3 shared
- Bing Ren3 shared
- Xiangmin Xu3 shared
- Karen H Ashe2 shared
- Ameeta Kelekar1 shared
- Neil Otto1 shared
Most similar at University Of Minnesota Twin Cities
Same institution · by research overlap
- Timothy J Ebner$23,147,993
Others in their field
Top investigators on “Alzheimer&Apos”
- Jose A Luchsinger · Columbia University Health Sciences$56,595,040
- Eric M Reiman · Banner Health$48,982,487
- Yadong Huang · J. David Gladstone Institutes$40,311,515
- Lindsay A. Farrer · Boston University Medical Campus$34,189,802
- David M Holtzman · Washington University$28,985,806
- Michael W Weiner · Northern California Institute Res &Educ$28,197,224
Research focus
Alzheimer&AposMouse ModelMolecularGenesS DiseaseTau ProteinsPathogenicityMutationTechnologyCellsGene ReplacementProteinsInsightMapt GeneVariantGenomicsTauopathiesFunctional DisorderAnimal ModelTherapeutic InterventionPhosphorylationPlayBrainHuman Disease
Grant awards (26)
Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regions$1,979,459
R01 · FY2025 · AG
Full human gene replacement mouse models of Alzheimer's Disease$1,321,156
R01 · FY2025 · AG · contact PI
Using a novel mTBI model to investigate phosphorylation dependent common mechanisms in tauopathies$751,906
R01 · FY2025 · AG
Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regions$2,019,855
R01 · FY2024 · AG
Using a novel mTBI model to investigate phosphorylation dependent common mechanisms in tauopathies$767,250
R01 · FY2024 · AG
Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regions$2,094,544
R01 · FY2023 · AG
Using a novel mTBI model to investigate phosphorylation dependent common mechanisms in tauopathies$767,250
R01 · FY2023 · AG
Full human gene replacement mouse models of Alzheimer's Disease$4,147,326
RF1 · FY2022 · AG · contact PI
Using a novel mTBI model to investigate phosphorylation dependent common mechanisms in tauopathies$767,250
R01 · FY2022 · AG
Full human gene-replacement mouse models of ADRDs$2,280,898
R33 · FY2021 · NS · contact PI
Matched sets of full human gene-replacement mouse lines for MODEL-AD$1,329,167
R56 · FY2021 · AG · contact PI
Generating a wild type and apoptosis-deficient human Noxa expressing BAC transgenic mouse$77,000
R03 · FY2020 · AI
Full human gene-replacement mouse models of ADRDs$1,507,494
R61 · FY2019 · NS · contact PI
Molecular endophenotypes of H1 and H2 MAPT haplotypes$192,500
R21 · FY2019 · AG
Molecular endophenotypes of H1 and H2 MAPT haplotypes$231,000
R21 · FY2018 · AG
Development of mitochondrial disease mouse models$224,856
R41 · FY2018 · OD
Towards gene therapy of mitochondrial disease$187,491
R21 · FY2010 · NS · contact PI
Towards gene therapy of mitochondrial disease$222,758
R21 · FY2009 · NS · contact PI
Mouse model of human diseases caused by mtDNA mutations$168,728
R21 · FY2006 · NS · contact PI
Molecular analysis of the genes involved in SCA8 ataxia$332,488
R01 · FY2005 · NS
Mouse model of human diseases caused by mtDNA mutations$165,785
R21 · FY2005 · NS
Molecular analysis of the genes involved in SCA8 ataxia$332,535
R01 · FY2004 · NS
Molecular analysis of the genes involved in SCA8 ataxia$332,582
R01 · FY2003 · NS
Molecular analysis of the genes involved in SCA8 ataxia$332,626
R01 · FY2002 · NS
Molecular analysis of the genes involved in SCA8 ataxia$329,275
R01 · FY2001 · NS
ISOLATING LONG CAG REPEATS DIRECTLY FROM ATAXIA PATIENTS$255,461
R01 · FY2000 · NS