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Christopher C. W. Hughes

University Of California Irvine

$22,189,863
Attributed
$34,257,710
Total exposure
25
Grants
16
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $4.4M · FY200525
$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$34,257,710 · 25

By mechanism

R01$10,441,782 · 7
UC4$6,890,666 · 2
UH3$5,347,780 · 2
UG3$5,067,920 · 3
R33$1,904,995 · 1
R21$1,559,518 · 4

Most similar at University Of California Irvine

Same institution · by research overlap

Others in their field

Top investigators on “Blood Vessels

Research focus

Blood VesselsCellsEndothelial CellsTissuesComplexIn VitroResponseMicrofluidicsOrganIn VivoMalignant NeoplasmsIn Vitro ModelBiologyUnited States National Institutes Of HealthBiomedical EngineeringStromal CellsGene ExpressionBlood CapillariesDevicesCapillaryTissue Engineering3-DimensionalInsulinNovel Therapeutics

Grant awards (78)

Bed to bench evaluation of cardiac and vascular impact of OSA$1,296,660
R01 · FY2025 · HL
Studying the mechanisms of initiation and progression of Beta cell death in T1D$1,232,846
UG3 · FY2025 · DK
A vascularized microphysiological system (MPS) platform for modeling peritoneal carcinomatosis$521,240
R01 · FY2025 · CA · contact PI
Repurposing drugs to treat Hereditary Hemorrhagic Telangiectasia: identification using a vascularized HHT on-a-chip microphysiological system platform$78,500
R03 · FY2025 · NS · contact PI
A Vascularized Micro-Organ platform for the study of Brain-BBB-Blood interaction$613,134
R33 · FY2024 · HL · contact PI
A vascularized microphysiological system (MPS) platform for modeling peritoneal carcinomatosis$501,606
R01 · FY2024 · CA · contact PI
In search of synergistic drug interactions in cancer$164,059
R21 · FY2024 · CA · contact PI
A 3D vascularized islet biomimetic to model type 1 diabetes$998,312
UH3 · FY2023 · DK
A Vascularized Micro-Organ platform for the study of Brain-BBB-Blood interaction$638,729
R33 · FY2023 · HL · contact PI
In search of synergistic drug interactions in cancer$205,740
R21 · FY2023 · CA · contact PI
A 3D vascularized islet biomimetic to model type 1 diabetes$1,009,781
UH3 · FY2022 · DK
A Vascularized Micro-Organ platform for the study of Brain-BBB-Blood interaction$653,132
R33 · FY2022 · HL · contact PI
Training Program in Cardiovascular Applied Research and Entrepreneurship$179,318
T32 · FY2022 · HL · contact PI
A 3D vascularized islet biomimetic to model type 1 diabetes$1,009,567
UH3 · FY2021 · DK
Microphysiological systems to model vascular malformations$716,989
UH3 · FY2021 · HL · contact PI
A Vascularized Micro-Organ platform for the study of Brain-BBB-Blood interaction$642,429
R61 · FY2021 · HL · contact PI
Training Program in Cardiovascular Applied Research and Entrepreneurship$179,884
T32 · FY2021 · HL · contact PI
A 3D vascularized islet biomimetic to model type 1 diabetes$1,035,118
UG3 · FY2020 · DK
Microphysiological systems to model vascular malformations$716,989
UH3 · FY2020 · HL · contact PI
A Vascularized Micro-Organ platform for the study of Brain-BBB-Blood interaction$640,807
R61 · FY2020 · HL · contact PI
MIcrophysiological systems to model vascular malformations$179,153
UH3 · FY2020 · HL · contact PI
Training Program in Cardiovascular Applied Research and Entrepreneurship$177,654
T32 · FY2020 · HL · contact PI
Onco-Imaging and Biotechnology Program (OIB)$24,825
P30 · FY2020 · CA · contact PI
A 3D vascularized islet biomimetic to model type 1 diabetes$1,087,069
UG3 · FY2019 · DK
Microphysiological systems to model vascular malformations$716,989
UH3 · FY2019 · HL · contact PI
Training Program in Cardiovascular Applied Research and Entrepreneurship$175,477
T32 · FY2019 · HL · contact PI
Onco-Imaging and Biotechnology Program (OIB)$24,825
P30 · FY2019 · CA · contact PI
Microphysiological systems to model vascular malformations$719,442
UG3 · FY2018 · HL · contact PI
Training Program in Cardiovascular Applied Research and Entrepreneurship$173,352
T32 · FY2018 · HL · contact PI
Onco-Imaging and Biotechnology Program (OIB)$24,825
P30 · FY2018 · CA · contact PI
Modular monitoring of hormone release from human islets$1,981,404
UC4 · FY2017 · DK
Microphysiological systems to model vascular malformations$993,445
UG3 · FY2017 · HL · contact PI
Real-time bioluminescent detection of circulating biomarkers$193,125
R21 · FY2017 · EB · contact PI
Training Program in Cardiovascular Applied Research and Entrepreneurship$160,782
T32 · FY2017 · HL · contact PI
Onco-Imaging and Biotechnology Program (OIB)$14,260
P30 · FY2017 · CA · contact PI
A 3-D biomimetic human islet to model beta cell function in health and disease$961,943
UC4 · FY2016 · DK
(PQD5) Development of in Vitro Vascularized Microtumors for Drug Screening$313,372
R01 · FY2016 · CA · contact PI
Real-time bioluminescent detection of circulating biomarkers$223,030
R21 · FY2016 · EB · contact PI
Training Program in Cardiovascular Applied Research and Entrepreneurship$162,738
T32 · FY2016 · HL · contact PI
A 3-D biomimetic human islet to model beta cell function in health and disease$33,480
UC4 · FY2016 · DK
Onco-Imaging and Biotechnology Program (OIB)$22,102
P30 · FY2016 · CA · contact PI
(PQD5) Development of in Vitro Vascularized Microtumors for Drug Screening$313,372
R01 · FY2015 · CA · contact PI
Training Program in Cardiovascular Applied Research and Entrepreneurship$160,768
T32 · FY2015 · HL · contact PI
A 3-D biomimetic human islet to model beta cell function in health and disease$3,913,839
UC4 · FY2014 · DK
(PQD5) Development of in Vitro Vascularized Microtumors for Drug Screening$303,971
R01 · FY2014 · CA · contact PI
Training Program in Cardiovascular Applied Research and Entrepreneurship$158,850
T32 · FY2014 · HL · contact PI
Molecular Approaches targeted on blocking angiogenesis$324,449
R01 · FY2013 · HL · contact PI
A 3-D in vitro platform of tumor metastasis (PQ24)$318,879
R01 · FY2013 · CA
(PQD5) Development of in Vitro Vascularized Microtumors for Drug Screening$312,400
R01 · FY2013 · CA · contact PI
GROWTH FACTORS & SIGNALING PROGRAM$10,562
P30 · FY2013 · CA · contact PI
Molecular Approaches targeted on blocking angiogenesis$340,808
R01 · FY2012 · HL · contact PI
A 3-D in vitro platform of tumor metastasis (PQ24)$338,175
R01 · FY2012 · CA
Encapsulated engineered microtumors: A platform for high throughput drug screenin$159,335
R21 · FY2012 · CA · contact PI
Molecular Approaches targeted on blocking angiogenesis$344,250
R01 · FY2011 · HL · contact PI
Encapsulated engineered microtumors: A platform for high throughput drug screenin$193,479
R21 · FY2011 · CA · contact PI
Creating a prevascularized thick implantable human tissue$191,250
R21 · FY2011 · HL
GROWTH FACTORS & SIGNALING PROGRAM$10,704
P30 · FY2011 · CA · contact PI
Bidirectional Notch Signaling and Angiogenesis$357,968
R01 · FY2010 · HL · contact PI
Molecular Approaches targeted on blocking angiogenesis$344,250
R01 · FY2010 · HL · contact PI
Creating a prevascularized thick implantable human tissue$229,500
R21 · FY2010 · HL
GROWTH FACTORS & SIGNALING PROGRAM$11,308
P30 · FY2010 · CA · contact PI
Bidirectional Notch Signaling and Angiogenesis$360,463
R01 · FY2009 · HL · contact PI
GROWTH FACTORS & SIGNALING PROGRAM$11,079
P30 · FY2009 · CA · contact PI
Bidirectional Notch Signaling and Angiogenesis$362,690
R01 · FY2008 · HL · contact PI
Bidirectional Notch Signaling and Angiogenesis$364,678
R01 · FY2007 · HL · contact PI
Molecular Approaches Targeted on Blocking Angiogenesis$253,495
R01 · FY2006 · HL · contact PI
Endothelial Cell Regulation of T Cell Activation$289,374
R01 · FY2005 · AI
Molecular Approaches Targeted on Blocking Angiogenesis$259,386
R01 · FY2005 · HL
Endothelial Cell Regulation of T Cell Activation$290,317
R01 · FY2004 · AI
Molecular Approaches Targeted on Blocking Angiogenesis$259,114
R01 · FY2004 · HL
Endothelial Cell Regulation of T Cell Activation$291,183
R01 · FY2003 · AI
Molecular Approaches Targeted on Blocking Angiogenesis$284,611
R01 · FY2003 · HL
Endothelial Cell Regulation of T Cell Activation$291,977
R01 · FY2002 · AI
MOLECULAR APPROACHES TARGETED ON BLOCKING ANGIOGENESIS$230,672
R01 · FY2002 · HL
Endothelial Cell Regulation of T Cell Activation$309,668
R01 · FY2001 · AI
MOLECULAR APPROACHES TARGETED ON BLOCKING ANGIOGENESIS$223,953
R01 · FY2001 · HL
ENDOTHELIAL REGULATION OF T CELL TRANSCRIPTION FACTORS$221,371
R01 · FY2000 · AI
MOLECULAR APPROACHES TARGETED ON BLOCKING ANGIOGENESIS$217,430
R01 · FY2000 · HL