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Leslie Michels Thompson

University Of California-Irvine

$23,343,376
Attributed
$37,929,935
Total exposure
21
Grants
18
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $7.3M · FY200625
$10M$7.5M$5M$2.5M$0
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$58,515,038 · 24

By mechanism

U54$19,232,677 · 5
P01$8,531,764 · 3
R35$7,363,617 · 1
R01$6,625,390 · 3
U24$5,119,718 · 3
RC2$3,776,244 · 1

Most similar at University Of California-Irvine

Same institution · by research overlap

Others in their field

Top investigators on “Huntington Disease

Research focus

Huntington DiseaseCellsNeuronsBaseNeurodegenerative DisordersInduced Pluripotent Stem CellResponseGenesPathogenesisProteinsMutantGeneticResourcesCell TypePathway InteractionsPhenotypeProgramsParkinson DiseaseMolecularCommunitiesPathologyTechnologyInnovationCollaborations

Grant awards (110)

Molecular Mechanisms of Pathogenesis in Huntington’s disease$1,172,286
R35 · FY2025 · NS · contact PI
Training Program in Stem Cell Translational Medicine for Neurological Disorders$332,444
T32 · FY2025 · NS · contact PI
Molecular Mechanisms of Pathogenesis in Huntington’s disease$1,137,118
R35 · FY2024 · NS · contact PI
A Vascularized Micro-Organ platform for the study of Brain-BBB-Blood interaction$613,134
R33 · FY2024 · HL
Training Program in Stem Cell Translational Medicine for Neurological Disorders$264,736
T32 · FY2024 · NS · contact PI
Molecular Mechanisms of Pathogenesis in Huntington’s disease$1,172,285
R35 · FY2023 · NS · contact PI
A Vascularized Micro-Organ platform for the study of Brain-BBB-Blood interaction$638,729
R33 · FY2023 · HL
Training Program in Stem Cell Translational Medicine for Neurological Disorders$335,084
T32 · FY2023 · NS · contact PI
Molecular Mechanisms of Pathogenesis in Huntington’s disease$1,172,286
R35 · FY2022 · NS · contact PI
A Vascularized Micro-Organ platform for the study of Brain-BBB-Blood interaction$653,132
R33 · FY2022 · HL
Molecular Mechanisms of Pathogenesis in Huntington’s disease$420,645
R35 · FY2022 · NS · contact PI
Training Program in Stem Cell Translational Medicine for Neurological Disorders$210,359
T32 · FY2022 · NS · contact PI
Molecular Mechanisms of Pathogenesis in Huntington’s disease$1,163,530
R35 · FY2021 · NS · contact PI
A Vascularized Micro-Organ platform for the study of Brain-BBB-Blood interaction$642,429
R61 · FY2021 · HL
Training Program in Stem Cell Translational Medicine for Neurological Disorders$293,873
T32 · FY2021 · NS · contact PI
Molecular Mechanisms of Pathogenesis in Huntington’s disease$1,125,467
R35 · FY2020 · NS · contact PI
From Structure to Therapy: The TRiC Chaperonin Network in Huntington's Disease$988,674
P01 · FY2020 · NS · contact PI
A Vascularized Micro-Organ platform for the study of Brain-BBB-Blood interaction$640,807
R61 · FY2020 · HL
Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$600,000
U54 · FY2020 · NS · contact PI
Project 3: TRiC modulation of CNS pathogenesis in HD mouse models$301,377
P01 · FY2020 · NS · contact PI
Training Program in Stem Cell Translational Medicine for Neurological Disorders$290,530
T32 · FY2020 · NS · contact PI
Core A: Administrative Core$57,570
P01 · FY2020 · NS · contact PI
Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$1,422,765
U54 · FY2019 · NS · contact PI
From Structure to Therapy: The TRiC Chaperonin Network in Huntington's Disease$1,293,620
P01 · FY2019 · NS · contact PI
Epigenetic pathology and therapy in Huntington's disease$554,354
R01 · FY2019 · NS
Project 3: TRiC modulation of CNS pathogenesis in HD mouse models$397,785
P01 · FY2019 · NS · contact PI
Training Program in Stem Cell Translational Medicine for Neurological Disorders$287,264
T32 · FY2019 · NS · contact PI
Core A: Administrative Core$83,453
P01 · FY2019 · NS · contact PI
Epigenetic pathology and therapy in Huntington's disease$67,210
R01 · FY2019 · NS
Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$1,334,000
U54 · FY2018 · NS · contact PI
From Structure to Therapy: The TRiC Chaperonin Network in Huntington's Disease$1,302,782
P01 · FY2018 · NS · contact PI
Data Generation Core - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$934,287
U54 · FY2018 · NS · contact PI
Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$833,765
U54 · FY2018 · NS · contact PI
Epigenetic pathology and therapy in Huntington's disease$554,354
R01 · FY2018 · NS
Neuroregulatory Mechanisms of PIAS1 and Implications for Huntington's Disease$436,818
R01 · FY2018 · NS · contact PI
Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells-Supplement$418,818
U54 · FY2018 · NS · contact PI
Project 3: TRiC modulation of CNS pathogenesis in HD mouse models$383,886
P01 · FY2018 · NS · contact PI
Data Analysis & sig - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$323,790
U54 · FY2018 · NS · contact PI
Training Program in Stem Cell Translational Medicine for Neurological Disorders$284,076
T32 · FY2018 · NS · contact PI
Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells-Supplement$107,536
U54 · FY2018 · NS · contact PI
Core A: Administrative Core$101,127
P01 · FY2018 · NS · contact PI
Administration - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$55,908
U54 · FY2018 · NS · contact PI
From Structure to Therapy: The TRiC Chaperonin Network in Huntington's Disease-Supplement for Equipment$40,000
P01 · FY2018 · NS · contact PI
Community Interactions Outreach - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$20,015
U54 · FY2018 · NS · contact PI
Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$2,167,765
U54 · FY2017 · NS · contact PI
Data Generation Core - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$1,527,239
U54 · FY2017 · NS · contact PI
From Structure to Therapy: The TRiC Chaperonin Network in Huntington's Disease$1,312,360
P01 · FY2017 · NS · contact PI
Epigenetic pathology and therapy in Huntington's disease$554,354
R01 · FY2017 · NS
Data Analysis & sig - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$520,751
U54 · FY2017 · NS · contact PI
Neuroregulatory Mechanisms of PIAS1 and Implications for Huntington's Disease$439,061
R01 · FY2017 · NS · contact PI
Project 3: TRiC modulation of CNS pathogenesis in HD mouse models$397,491
P01 · FY2017 · NS · contact PI
Training Program in Stem Cell Translational Medicine for Neurological Disorders$135,673
T32 · FY2017 · NS · contact PI
Administration - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$87,390
U54 · FY2017 · NS · contact PI
Core A: Administrative Core$83,384
P01 · FY2017 · NS · contact PI
Community Interactions Outreach - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$32,385
U54 · FY2017 · NS · contact PI
From Structure to Therapy: The TRiC Chaperonin Network in Huntington's Disease$12,067
P01 · FY2017 · NS · contact PI
Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$1,334,000
U54 · FY2016 · NS · contact PI
From Structure to Therapy: The TRiC Chaperonin Network in Huntington's Disease$1,311,829
P01 · FY2016 · NS · contact PI
Data Generation Core - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$934,285
U54 · FY2016 · NS · contact PI
Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$833,765
U54 · FY2016 · NS · contact PI
Epigenetic pathology and therapy in Huntington's disease$554,354
R01 · FY2016 · NS
Neuroregulatory Mechanisms of PIAS1 and Implications for Huntington's Disease$445,378
R01 · FY2016 · NS · contact PI
Project 3: TRiC modulation of CNS pathogenesis in HD mouse models$387,157
P01 · FY2016 · NS · contact PI
Data Analysis & sig - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$323,788
U54 · FY2016 · NS · contact PI
Genome editing in HD iPS cells to reduce mutant and total Huntington expression$254,075
R21 · FY2016 · NS · contact PI
Training Program in Stem Cell Translational Medicine for Neurological Disorders$152,396
T32 · FY2016 · NS · contact PI
Core A: Administrative Core$77,202
P01 · FY2016 · NS · contact PI
Administration - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$55,910
U54 · FY2016 · NS · contact PI
Community Interactions Outreach - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$20,017
U54 · FY2016 · NS · contact PI
Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$8,498
U54 · FY2016 · NS · contact PI
Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$1,334,000
U54 · FY2015 · NS · contact PI
Data Generation Core - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$934,286
U54 · FY2015 · NS · contact PI
Epigenetic pathology and therapy in Huntington's disease$554,354
R01 · FY2015 · NS
Neuroregulatory Mechanisms of PIAS1 and Implications for Huntington's Disease$465,277
R01 · FY2015 · NS · contact PI
Data Analysis & sig - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$317,686
U54 · FY2015 · NS · contact PI
Genome editing in HD iPS cells to reduce mutant and total Huntington expression$193,125
R21 · FY2015 · NS · contact PI
Training Program in Stem Cell Translational Medicine for Neurological Disorders$150,427
T32 · FY2015 · NS · contact PI
In vivo longitudinal assessment of methylene blue for Huntington's disease$77,250
R03 · FY2015 · NS · contact PI
Administration - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$55,910
U54 · FY2015 · NS · contact PI
Epigenetic pathology and therapy in Huntington's disease$50,000
R01 · FY2015 · NS
Training Program in Stem Cell Translational Medicine for Neurological Disorders$37,607
T32 · FY2015 · NS · contact PI
Community Interactions Outreach - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$26,118
U54 · FY2015 · NS · contact PI
Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$1,334,000
U54 · FY2014 · NS · contact PI
Data Generation Core - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$940,394
U54 · FY2014 · NS · contact PI
Neuroregulatory Mechanisms of PIAS1 and Implications for Huntington's Disease$564,939
R56 · FY2014 · NS · contact PI
Data Analysis & sig - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$310,155
U54 · FY2014 · NS · contact PI
Training Program in Stem Cell Translational Medicine for Neurological Disorders$149,157
T32 · FY2014 · NS · contact PI
In vivo longitudinal assessment of methylene blue for Huntington's disease$77,041
R03 · FY2014 · NS · contact PI
Administration - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$55,910
U54 · FY2014 · NS · contact PI
Community Interactions Outreach - Neuron and Glial Cellular Signatures from Normal and Diseased iPS Cells$27,541
U54 · FY2014 · NS · contact PI
The HD iPSC Consortium: Repeat Length Dependent Phenotypes for Assay Development$1,200,435
U24 · FY2013 · NS · contact PI
IPS (HD) Generation and Characterization$600,219
U24 · FY2013 · NS · contact PI
The Huntington's disease (HD) IPS consortium$600,216
U24 · FY2013 · NS · contact PI
Training Program in Stem Cell Translational Medicine for Neurological Disorders$146,591
T32 · FY2013 · NS · contact PI
The HD iPSC Consortium: Repeat Length Dependent Phenotypes for Assay Development$70,000
U24 · FY2013 · NS · contact PI
CAG Triplet Repeat Disorders$20,000
R13 · FY2013 · NS · contact PI
The HD iPSC Consortium: Repeat Length Dependent Phenotypes for Assay Development$1,324,424
U24 · FY2012 · NS · contact PI
IPS (HD) Generation and Characterization$662,213
U24 · FY2012 · NS · contact PI
The Huntington's disease (HD) IPS consortium$662,211
U24 · FY2012 · NS · contact PI
The Histone Demethylase SMCX/JARED1C as a Therapeutic Target for Huntington's Dis$191,250
R21 · FY2012 · NS · contact PI
The Histone Demethylase SMCX/JARED1C as a Therapeutic Target for Huntington's Dis$229,500
R21 · FY2011 · NS · contact PI
The Huntington's Disease iPS Consortium$1,839,894
RC2 · FY2010 · NS · contact PI
Pathogenic Impact of SUMO modification in Huntington's disease$329,842
R01 · FY2010 · NS · contact PI
The Huntington's Disease iPS Consortium$76,500
RC2 · FY2010 · NS · contact PI
The Huntington's Disease iPS Consortium$1,859,850
RC2 · FY2009 · NS · contact PI
Pathogenic Impact of SUMO modification in Huntington's disease$333,174
R01 · FY2009 · NS · contact PI
Pathogenic Impact of SUMO modification in Huntington's disease$277,387
R01 · FY2009 · NS · contact PI
Pathogenic Impact of SUMO modification in Huntington's disease$333,174
R01 · FY2008 · NS · contact PI
Pathogenic Impact of SUMO modification in Huntington's disease$333,174
R01 · FY2007 · NS · contact PI
Pathogenic Impact of SUMO modification in Huntington's disease$343,125
R01 · FY2006 · NS · contact PI