← Leaderboards
Lennart Mucke
Scripps Research Institute
$61,251,241
Attributed
$61,251,241
Total exposure
36
Grants
33
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants. They are the sole PI on all grants (the two match).
Funding over time
peak $9.4M · FY2005–25$10M$7.5M$5M$2.5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$111,698,627 · 38
By mechanism
P01$62,596,975 · 12
R01$20,355,275 · 6
RF1$11,744,965 · 3
P30$5,695,876 · 2
R37$4,868,493 · 1
P50$2,613,932 · 3
Top collaborators
- Yadong Huang8 shared
Most similar at Scripps Research Institute
Same institution · by research overlap
- John Johnson$22,284,193
Others in their field
Top investigators on “Alzheimer&Apos”
- Jose A Luchsinger · Columbia University Health Sciences$56,595,040
- Eric M Reiman · Banner Health$48,982,487
- Yadong Huang · J. David Gladstone Institutes$40,311,515
- Lindsay A. Farrer · Boston University Medical Campus$34,189,802
- David M Holtzman · Washington University$28,985,806
- Michael W Weiner · Northern California Institute Res &Educ$28,197,224
Research focus
Alzheimer&AposMouse ModelNeuronsS DiseaseBrainPreventSynapsesPathogenesisMolecularTau ProteinsAffectBehavioralImpaired CognitionCognitive DeficitsProteinsMediatingTransgenic OrganismsLinkAmyloid Beta-Protein PrecursorLearningAmyloid Beta-ProteinApolipoprotein EImpairmentFunding
Grant awards (139)
Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease$4,564,091
P01 · FY2025 · AG · contact PI
Project 3: Roles of Tau Levels, Sequence and Interactors in Neural Network Dysfunction of Alzheimer's Disease$837,668
P01 · FY2025 · AG · contact PI
Core A: Administrative Core$209,049
P01 · FY2025 · AG · contact PI
Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease$4,657,774
P01 · FY2024 · AG · contact PI
Project 3: Roles of Tau Levels, Sequence and Interactors in Neural Network Dysfunction of Alzheimer's Disease$1,101,037
P01 · FY2024 · AG · contact PI
Core A: Administrative Core$157,034
P01 · FY2024 · AG · contact PI
Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease$4,657,222
P01 · FY2023 · AG · contact PI
Roles of TREM2 and TYROBP in AD-related Network Hyperexcitability$2,833,089
RF1 · FY2023 · AG · contact PI
Project 3: Roles of Tau Levels, Sequence and Interactors in Neural Network Dysfunction of Alzheimer's Disease$1,107,277
P01 · FY2023 · AG · contact PI
Transcriptomic and Proteomic Analysis of Tau-dependent E/I Imbalance$519,750
R21 · FY2023 · AG · contact PI
Core A: Administrative Core$173,571
P01 · FY2023 · AG · contact PI
Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease$65,507
P01 · FY2023 · AG · contact PI
Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease$4,611,009
P01 · FY2022 · AG · contact PI
Project 3: Roles of Tau Levels, Sequence and Interactors in Neural Network Dysfunction of Alzheimer's Disease$867,557
P01 · FY2022 · AG · contact PI
Therapeutic Potential and Mechanisms of Tau Reduction in Autism Models$717,125
R01 · FY2022 · MH · contact PI
Core A: Administrative Core$198,413
P01 · FY2022 · AG · contact PI
Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease$157,218
P01 · FY2022 · AG · contact PI
Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease$91,710
P01 · FY2022 · AG · contact PI
Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease$4,626,857
P01 · FY2021 · AG · contact PI
Project 3: Roles of Tau Levels, Sequence and Interactors in Neural Network Dysfunction of Alzheimer's Disease$888,001
P01 · FY2021 · AG · contact PI
Therapeutic Potential and Mechanisms of Tau Reduction in Autism Models$717,125
R01 · FY2021 · MH · contact PI
Core A: Administrative Core$176,406
P01 · FY2021 · AG · contact PI
Therapeutic Potential and Mechanisms of Tau Reduction in Autism Models$717,125
R01 · FY2020 · MH · contact PI
Evolving CRISPR-based platforms for the discovery of Alzheimer relevant neurodegenerative pathways$519,750
R21 · FY2020 · AG · contact PI
Neural network and immune cell dysfunctions in Alzheimer's disease pathogenesis$472,487
RF1 · FY2020 · AG · contact PI
Effect of Aging on Efficacy of Alzheimer-focused Therapeutic Strategies$168,462
UH3 · FY2020 · NS · contact PI
Neural network and immune cell dysfunctions in Alzheimer's disease pathogenesis$4,538,275
RF1 · FY2019 · AG · contact PI
Identification and Development of Tau-Lowering Small-Molecule Drugs$1,703,867
R56 · FY2019 · AG · contact PI
Therapeutic Potential and Mechanisms of Tau Reduction in Autism Models$717,125
R01 · FY2019 · MH · contact PI
Effect of Aging on Efficacy of Alzheimer-focused Therapeutic Strategies$173,086
UH3 · FY2019 · NS · contact PI
Therapeutic Potential and Mechanisms of Tau Reduction in Autism Models$750,148
R01 · FY2018 · MH · contact PI
Neurobiology and Therapeutic Potential of Klotho$708,482
R01 · FY2018 · NS · contact PI
Effect of Aging on Efficacy of Alzheimer-focused Therapeutic Strategies$162,055
UH3 · FY2018 · NS · contact PI
Neurobiology and Therapeutic Potential of Klotho$708,482
R01 · FY2017 · NS · contact PI
Synaptic Dysfunction Affecting DNA Integrity in Alzheimer's Disease$447,767
R01 · FY2017 · AG · contact PI
Contribution of DNA Repair Deficits to Alzheimer Pathogenesis$186,249
RF1 · FY2017 · AG · contact PI
Effect of Aging on Efficacy of Alzheimer-focused Therapeutic Strategies$64,024
UH2 · FY2017 · NS · contact PI
Contribution of DNA Repair Deficits to Alzheimer Pathogenesis$3,714,865
RF1 · FY2016 · AG · contact PI
Neurobiology and Therapeutic Potential of Klotho$708,482
R01 · FY2016 · NS · contact PI
Synaptic Dysfunction Affecting DNA Integrity in Alzheimer's Disease$449,343
R01 · FY2016 · AG · contact PI
Effect of Aging on Efficacy of Alzheimer-focused Therapeutic Strategies$32,368
UH2 · FY2016 · NS · contact PI
Behavioral Core$816,807
P30 · FY2015 · NS · contact PI
Neurobiology and Therapeutic Potential of Klotho$708,482
R01 · FY2015 · NS · contact PI
Kinases Linking Abeta and Tau to Synaptic Dysfunction$462,472
R01 · FY2015 · NS · contact PI
Synaptic Dysfunction Affecting DNA Integrity in Alzheimer's Disease$440,291
R01 · FY2015 · AG · contact PI
Behavioral Core$816,054
P30 · FY2014 · NS · contact PI
Neurobiology and Therapeutic Potential of Klotho$708,482
R01 · FY2014 · NS · contact PI
Kinases Linking Abeta and Tau to Synaptic Dysfunction$457,848
R01 · FY2014 · NS · contact PI
Synaptic Dysfunction Affecting DNA Integrity in Alzheimer's Disease$452,312
R01 · FY2014 · AG · contact PI
Behavioral Core$811,046
P30 · FY2013 · NS · contact PI
Synaptic Dysfunction Affecting DNA Integrity in Alzheimer's Disease$476,523
R01 · FY2013 · AG · contact PI
Kinases Linking Abeta and Tau to Synaptic Dysfunction$446,285
R01 · FY2013 · NS · contact PI
POTENTIAL ROLE OF EPILEPSY IN ALZHEIMER? DISEASE$177,498
P50 · FY2013 · AG · contact PI
Proteinopathies of the Aging Central Nervous System$1,943,801
P01 · FY2012 · AG · contact PI
Behavioral Core$803,292
P30 · FY2012 · NS · contact PI
Kinases Linking Abeta and Tau to Synaptic Dysfunction$462,472
R01 · FY2012 · NS · contact PI
Mechanisms of AB-induced Neuronal Deficits$262,132
P01 · FY2012 · AG · contact PI
Animal Core$240,940
P01 · FY2012 · AG · contact PI
POTENTIAL ROLE OF EPILEPSY IN ALZHEIMER? DISEASE$201,456
P50 · FY2012 · AG · contact PI
Mouse Models with Regulatable Cell Type-specific Expression of Anti-Tau shRNAs$158,260
R21 · FY2012 · AG · contact PI
Administrative Core$140,729
P01 · FY2012 · AG · contact PI
Proteinopathies of the Aging Central Nervous System$3,948,699
P01 · FY2011 · AG · contact PI
Behavioral Core$720,677
P30 · FY2011 · NS · contact PI
Mechanisms of AB-induced Neuronal Deficits$528,075
P01 · FY2011 · AG · contact PI
Animal Core$518,210
P01 · FY2011 · AG · contact PI
Transgenic Models to Study Alzheimer's Disease$485,073
R37 · FY2011 · AG · contact PI
Kinases Linking Abeta and Tau to Synaptic Dysfunction$460,120
R01 · FY2011 · NS · contact PI
Administrative Core$283,507
P01 · FY2011 · AG · contact PI
Mouse Models with Regulatable Cell Type-specific Expression of Anti-Tau shRNAs$276,955
R21 · FY2011 · AG · contact PI
POTENTIAL ROLE OF EPILEPSY IN ALZHEIMER? DISEASE$196,110
P50 · FY2011 · AG · contact PI
Kinases Linking Abeta and Tau to Synaptic Dysfunction$95,309
R01 · FY2011 · NS · contact PI
PHOSPHOPROTEOMIC ANALYSIS OF SYNAPTIC PROTEINS IN ALZHEIMER DISEASE MOUSE MODELS$21,188
P41 · FY2011 · RR · contact PI
DIFFERENCES IN POST-TRANSLATIONAL MODIFICATION OF TAU IN HAPP VS NORMAL MICE$8,515
P41 · FY2011 · RR · contact PI
Proteinopathies of the Aging Central Nervous System$3,051,367
P01 · FY2010 · AG · contact PI
Novel Therapeutic Approaches to Alzheimer's Disease$864,000
P30 · FY2010 · NS · contact PI
Roles of Amyloid Precursor Protein and its Metabolites in Neuronal Impairment$538,442
R01 · FY2010 · NS · contact PI
Transgenic Models to Study Alzheimer's Disease$491,343
R37 · FY2010 · AG · contact PI
Animal Core$475,052
P01 · FY2010 · AG · contact PI
Mechanisms of AB-induced Neuronal Deficits$408,025
P01 · FY2010 · AG · contact PI
Administrative Core$219,055
P01 · FY2010 · AG · contact PI
POTENTIAL ROLE OF EPILEPSY IN ALZHEIMER? DISEASE$194,792
P50 · FY2010 · AG · contact PI
Proteinopathies of the Aging Central Nervous System$74,295
P01 · FY2010 · AG · contact PI
PHOSPHOPROTEOMIC ANALYSIS OF SYNAPTIC PROTEINS IN ALZHEIMER DISEASE MOUSE MODELS$7,066
P41 · FY2010 · RR · contact PI
DIFFERENCES IN POST-TRANSLATIONAL MODIFICATION OF TAU IN HAPP VS NORMAL MICE$3,533
P41 · FY2010 · RR · contact PI
Proteinopathies of the Aging Central Nervous System$3,028,460
P01 · FY2009 · AG · contact PI
Novel Therapeutic Approaches to Alzheimer's Disease$864,000
P30 · FY2009 · NS · contact PI
Roles of Amyloid Precursor Protein and its Metabolites in Neuronal Impairment$527,098
R01 · FY2009 · NS · contact PI
Transgenic Models to Study Alzheimer's Disease$483,286
R37 · FY2009 · AG · contact PI
Animal Core$480,741
P01 · FY2009 · AG · contact PI
Mechanisms of AB-induced Neuronal Deficits$390,631
P01 · FY2009 · AG · contact PI
Administrative Core$209,715
P01 · FY2009 · AG · contact PI
POTENTIAL ROLE OF EPILEPSY IN ALZHEIMER? DISEASE$191,000
P50 · FY2009 · AG · contact PI
Roles of Amyloid Precursor Protein and its Metabolites in Neuronal Impairment$98,812
R01 · FY2009 · NS · contact PI
PHOSPHOPROTEOMIC ANALYSIS OF SYNAPTIC PROTEINS IN ALZHEIMER'S DISEASE$4,232
P41 · FY2009 · RR · contact PI
Proteinopathies of the Aging Central Nervous System$2,943,317
P01 · FY2008 · AG · contact PI
Roles of Amyloid Precursor Protein and its Metabolites in Neuronal Impairment$510,839
R01 · FY2008 · NS · contact PI
Transgenic Models to Study Alzheimer's Disease$470,681
R37 · FY2008 · AG · contact PI
Mechanisms of AB-induced Neuronal Deficits$401,999
P01 · FY2008 · AG · contact PI
Animal Core$391,552
P01 · FY2008 · AG · contact PI
MOLECULAR INDICATORS OF DEMENTIA RELATED DEFICITS$313,381
P50 · FY2008 · AG · contact PI
Administrative Core$203,606
P01 · FY2008 · AG · contact PI
Proteopathies of the Aging Central Nervous System$2,402,472
P01 · FY2007 · AG · contact PI
Roles of Amyloid Precursor Protein and its Metabolites in Neuronal Impairment$495,095
R01 · FY2007 · NS · contact PI
Transgenic Models to Study Alzheimer's Disease$490,830
R37 · FY2007 · AG · contact PI
CORE--ANIMAL$322,892
P01 · FY2007 · AG · contact PI
MECHANISMS OF AMYLOID BETA PEPTIDE-INDUCED NEURONAL DEFICITS$320,892
P01 · FY2007 · AG · contact PI
MOLECULAR INDICATORS OF DEMENTIA RELATED DEFICITS$305,211
P50 · FY2007 · AG · contact PI
Administrative Core$202,620
P01 · FY2007 · AG · contact PI
Proteopathies of the Aging Central Nervous$90,000
P01 · FY2007 · AG · contact PI
Proteopathies of the Aging Central Nervous$2,465,000
P01 · FY2006 · AG · contact PI
Transgenic Models to Study Alzheimer's Disease$521,346
R37 · FY2006 · AG · contact PI
Role of APP and its Metabolites in Synaptic Degeneration$494,166
R01 · FY2006 · NS · contact PI
MOLECULAR INDICATORS OF DEMENTIA RELATED DEFICITS$236,182
P50 · FY2006 · AG · contact PI
MECHANISMS OF AB-INDUCED NEURONAL DEFICITS$223,788
P01 · FY2006 · AG · contact PI
CORE--ANIMAL$209,415
P01 · FY2006 · AG · contact PI
Proteopathies of the Aging Central Nervous$2,495,388
P01 · FY2005 · AG
A Beta Vaccination: Mechanisms and Therapautic Impact$614,765
R01 · FY2005 · NS
Transgenic Models to Study Alzheimer's Disease$520,654
R37 · FY2005 · AG
MOLECULAR INDICATORS OF DEMENTIA RELATED DEFICITS$230,219
P50 · FY2005 · AG
Proteopathies of the Aging Central Nervous$2,299,012
P01 · FY2004 · AG
A Beta Vaccination: Mechanisms and Therapautic Impact$643,533
R01 · FY2004 · NS
Role of APP and its Metabolites in Synaptic Degeneration$492,480
R01 · FY2004 · NS
Transgenic Models to Study Alzheimer's Disease$480,811
R37 · FY2004 · AG
MOLECULAR INDICATORS OF DEMENTIA RELATED DEFICITS$230,930
P50 · FY2004 · AG
Proteopathies of the Aging Central Nervous$50,000
P01 · FY2004 · AG
Proteopathies of the Aging Central Nervous System$2,224,187
P01 · FY2003 · AG
A Beta Vaccination: Mechanisms and Therapautic Impact$502,731
R01 · FY2003 · NS
Transgenic Models to Study Alzheimer's Disease$468,997
R37 · FY2003 · AG
Role of APP and its Metabolites in Synaptic Degeneration$445,000
R01 · FY2003 · NS
A Beta Vaccination: Mechanisms and Therapautic Impact$509,683
R01 · FY2002 · NS
Transgenic Models to Study Alzheimer's Disease$455,472
R37 · FY2002 · AG
Role of APP and its Metabolites in Synaptic Degeneration$445,000
R01 · FY2002 · NS
A Beta Vaccination: Mechanisms and Therapautic Impact$513,002
R01 · FY2001 · NS
Role of APP and its Metabolites in Synaptic Degeneration$445,000
R01 · FY2001 · NS
TRANSGENIC MODELS TO SUDY ALZHEIMERS DISEASE$403,702
R01 · FY2001 · AG
TRANSGENIC MODELS TO SUDY ALZHEIMERS DISEASE$393,715
R01 · FY2000 · AG
MOLECULAR MECHANISMS OF HIV-1 NEUROTOXICITY$337,153
P50 · FY2000 · MH
THERAPEUTIC TARGETS IN TRANSGENIC MICE$301,462
R01 · FY2000 · MH
TRANSGENIC MODELS TO SUDY ALZHEIMERS DISEASE$168,950
R01 · FY2000 · AG