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Tsan Sam Xiao

Case Western Reserve University

$5,838,475
Attributed
$5,838,475
Total exposure
6
Grants
6
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants. They are the sole PI on all grants (the two match).

Funding over time

peak $1.1M · FY201625
$2M$1.5M$1M$500K$0
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$5,838,475 · 6

By mechanism

R01$2,270,751 · 2
P01$2,012,502 · 1
R35$1,010,652 · 1
R21$383,570 · 1
R03$161,000 · 1

Top collaborators

No co-investigators on record.

Most similar at Case Western Reserve University

Same institution · by research overlap

Others in their field

Top investigators on “Mediating

Research focus

MediatingCell DeathRegulationInflammatoryInsightStructureCaspaseInflammasomeInfectionMolecularS DiseaseProteinsCasp1 GeneImmuneBiochemicalPlaySuccessImmune SignalingAlzheimer&AposComplexTherapeutic DevelopmentLengthMembraneSignal Pathway

Grant awards (21)

Regulation of gasdermins through protease processing and other post-translational modifications.$402,500
R35 · FY2025 · GM · contact PI
Molecular mechanisms of gasdermin recognition by proteases and autophagy proteins in cytokine release$402,502
P01 · FY2024 · AI · contact PI
Regulation of gasdermins through protease processing and other post-translational modifications.$402,500
R35 · FY2024 · GM · contact PI
Regulation of gasdermins through protease processing and other post-translational modifications.$205,652
R35 · FY2024 · GM · contact PI
Structural studies of gasdermin E and its recognition by caspase-3.$80,500
R03 · FY2024 · AI · contact PI
Mechanisms of tunable posttranslational control of T-cell homeostasis and tolerance$425,980
R01 · FY2023 · AI · contact PI
Molecular mechanisms of gasdermin recognition by proteases and autophagy proteins in cytokine release$402,500
P01 · FY2023 · AI · contact PI
Structural studies of gasdermin E and its recognition by caspase-3.$80,500
R03 · FY2023 · AI · contact PI
Mechanisms of tunable posttranslational control of T-cell homeostasis and tolerance$425,980
R01 · FY2022 · AI · contact PI
Molecular mechanisms of gasdermin recognition by proteases and autophagy proteins in cytokine release$402,500
P01 · FY2022 · AI · contact PI
Molecular mechanisms of gasdermin recognition by proteases and autophagy proteins in cytokine release$402,500
P01 · FY2021 · AI · contact PI
Molecular mechanisms of gasdermins and pyroptosis$305,900
R01 · FY2021 · GM · contact PI
Molecular mechanisms of gasdermin recognition by proteases and autophagy proteins in cytokine release$402,500
P01 · FY2020 · AI · contact PI
Molecular mechanisms of gasdermins and pyroptosis$305,267
R01 · FY2020 · GM · contact PI
Molecular mechanisms of gasdermins and pyroptosis$304,000
R01 · FY2019 · GM · contact PI
Molecular mechanisms of gasdermins and pyroptosis$80,062
R01 · FY2019 · GM · contact PI
Molecular mechanisms of gasdermins and pyroptosis$304,000
R01 · FY2018 · GM · contact PI
Molecular mechanisms of gasdermins and pyroptosis$67,592
R01 · FY2018 · GM · contact PI
Molecular mechanisms of gasdermins and pyroptosis$51,970
R01 · FY2018 · GM · contact PI
Developing chemical probes that target specific inflammasomes$174,350
R21 · FY2017 · AR · contact PI
Developing chemical probes that target specific inflammasomes$209,220
R21 · FY2016 · AR · contact PI