← Leaderboards
George R Dubyak
Case Western Reserve University
$11,095,573
Attributed
$13,047,023
Total exposure
7
Grants
5
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $3.1M · FY2005–25$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$24,523,121 · 9
By mechanism
P01$14,871,414 · 5
R01$7,520,512 · 2
T32$1,685,677 · 1
R21$445,518 · 1
Top collaborators
- Eric Pearlman8 shared
- Arne Rietsch2 shared
Most similar at Case Western Reserve University
Same institution · by research overlap
- Eric Pearlman$20,900,586
- Rossana Occhipinti$760,668
- Arne Rietsch$5,356,051
- Liem Duy Nguyen$2,802,112
Others in their field
Top investigators on “Signal Transduction”
- Peter B. Gilbert · Fred Hutchinson Cancer Center$148,539,615
- David Heimbrook · Leidos Biomedical Research, Inc.$82,049,940
- Margaret Juliana McElrath · Fred Hutchinson Cancer Center$70,290,471
- Garret A Fitzgerald · University Of Pennsylvania$66,142,222
- Michael Barry Kastan · Duke University$64,512,357
- Randall J Bateman · Washington University$62,939,456
Research focus
Signal TransductionCytokineRegulationMacrophageCellsInflammatoryInflammasomeReportingResponseCell DeathTissuesInterleukin-1 BetaPathway InteractionsMediatingStimulusCaspaseInflammationExtracellularNeutrophilMicrobialTraffickingProteinsEffector CellMolecular
Grant awards (45)
Pathogenesis of Bacterial Keratitis$676,812
R01 · FY2025 · EY
Inflammasome and Gasdermin Signaling Networks for Regulation of Pyroptosis and Cytokine Release$1,886,706
P01 · FY2024 · AI · contact PI
Pathogenesis of Bacterial Keratitis$705,516
R01 · FY2024 · EY
Alternative pathways of gasdermin function and IL-1beta secretion in granulocytic leukocytes$410,011
P01 · FY2024 · AI · contact PI
Administrative Core$104,705
P01 · FY2024 · AI · contact PI
Inflammasome and Gasdermin Signaling Networks for Regulation of Pyroptosis and Cytokine Release$1,886,706
P01 · FY2023 · AI · contact PI
Alternative pathways of gasdermin function and IL-1beta secretion in granulocytic leukocytes$410,012
P01 · FY2023 · AI · contact PI
Administrative Core$104,706
P01 · FY2023 · AI · contact PI
Inflammasome and Gasdermin Signaling Networks for Regulation of Pyroptosis and Cytokine Release$1,886,706
P01 · FY2022 · AI · contact PI
Alternative pathways of gasdermin function and IL-1beta secretion in granulocytic leukocytes$410,012
P01 · FY2022 · AI · contact PI
Innate immunity in bacterial keratitis$397,702
R01 · FY2022 · EY
The role of Gasdermin E (DFNA5) in bacterial keratitis$192,768
R21 · FY2022 · EY
Administrative Core$104,705
P01 · FY2022 · AI · contact PI
Inflammasome and Gasdermin Signaling Networks for Regulation of Pyroptosis and Cytokine Release$1,886,706
P01 · FY2021 · AI · contact PI
Alternative pathways of gasdermin function and IL-1beta secretion in granulocytic leukocytes$410,014
P01 · FY2021 · AI · contact PI
Innate immunity in bacterial keratitis$397,701
R01 · FY2021 · EY
The role of Gasdermin E (DFNA5) in bacterial keratitis$252,750
R21 · FY2021 · EY
Administrative Core$104,705
P01 · FY2021 · AI · contact PI
Inflammasome and Gasdermin Signaling Networks for Regulation of Pyroptosis and Cytokine Release$1,886,706
P01 · FY2020 · AI · contact PI
Alternative pathways of gasdermin function and IL-1beta secretion in granulocytic leukocytes$410,014
P01 · FY2020 · AI · contact PI
Innate immunity in bacterial keratitis$410,000
R01 · FY2020 · EY
Administrative Core$104,705
P01 · FY2020 · AI · contact PI
Innate immunity in bacterial keratitis$408,875
R01 · FY2019 · EY
Regulation of Caspase-1 Signaling and Inflammation by the P2X7 ATP Receptor$379,694
R01 · FY2014 · GM · contact PI
Regulation of Caspase-1 Signaling and Inflammation by the P2X7 ATP Receptor$366,404
R01 · FY2013 · GM · contact PI
Regulation of Caspase-1 Signaling and Inflammation by the P2X7 ATP Receptor$379,694
R01 · FY2012 · GM · contact PI
Regulation of Caspase-1 Signaling and Inflammation by the P2X7 ATP Receptor$379,694
R01 · FY2011 · GM · contact PI
Regulation of Caspase-1 Signaling and Inflammation by the P2X7 ATP Receptor$351,797
R01 · FY2010 · GM · contact PI
Regulation of Caspase-1 Signaling and Inflammation by the P2X7 ATP Receptor$355,350
R01 · FY2009 · GM · contact PI
Regulation of Caspase-1 Signaling and Inflammation by the P2X7 ATP Receptor$355,350
R01 · FY2008 · GM · contact PI
Cleveland Training Program in Cardiovascular Research$212,914
T32 · FY2008 · HL · contact PI
Cleveland Training Program in Cardiovascular Research$588,999
T32 · FY2007 · HL · contact PI
Regulation of Caspase-1 Signaling and Inflammation by the P2X7 ATP Receptor$355,350
R01 · FY2007 · GM · contact PI
ATP Utilization and Ion Gradients in Myocardium$1,024,234
P01 · FY2006 · HL · contact PI
Cleveland Training Program in Cardiovascular Research$296,385
T32 · FY2006 · HL · contact PI
RELEASE AND METABOLISM OF EXTRACELLULAR ATP IN THE HEART$262,221
P01 · FY2006 · HL · contact PI
ATP Utilization and Ion Gradients in Myocardium$1,018,334
P01 · FY2005 · HL
Cleveland Training Program in Cardiovascular Research$587,379
T32 · FY2005 · HL
Protease-Based Signaling by the P2X7 Nucleotide Receptor$328,950
R01 · FY2005 · GM
RELEASE AND METABOLISM OF EXTRACELLULAR ATP IN THE HEART$254,583
P01 · FY2005 · HL
Protease-Based Signaling by the P2X7 Nucleotide Receptor$328,950
R01 · FY2004 · GM
Protease-Based Signaling by the P2X7 Nucleotide Receptor$328,950
R01 · FY2003 · GM
Protease-Based Signaling by the P2X7 Nucleotide Receptor$321,354
R01 · FY2002 · GM
RELEASE AND METABOLISM OF EXTRACELLULAR ATP IN THE HEART$304,923
P01 · FY2002 · HL
ATP RECEPTORS IN MACROPHAGES AND MONOCYTES$292,369
R01 · FY2000 · GM