← Leaderboards
Charles Scott Craik
University Of California, San Francisco
$31,131,909
Attributed
$38,127,880
Total exposure
40
Grants
26
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $6.6M · FY2005–25$10M$7.5M$5M$2.5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$38,127,880 · 40
By mechanism
R01$11,164,544 · 7
T32$7,812,287 · 1
U19$5,168,269 · 1
P50$5,045,277 · 4
P01$3,644,426 · 5
RF1$2,240,412 · 1
Top collaborators
- Michael John Evans11 shared
- Rahul Aggarwal7 shared
- David M Wilson4 shared
- Lawrence Fong3 shared
- Jason E Gestwicki2 shared
- Kimberly Saunders Kirkwood2 shared
- Daniel Ryland Southworth2 shared
Most similar at University Of California, San Francisco
Same institution · by research overlap
- Michael John Evans$10,372,266
- Rahul Aggarwal$5,953,056
- Thomas Hope$3,566,163
- Felix Yi-Chung Feng$6,764,664
- Lawrence Fong$19,816,074
Others in their field
Top investigators on “Peptide Hydrolases”
- John Damon Chodera · Sloan-Kettering Inst Can Research$39,488,414
- David Heimbrook · Leidos Biomedical Research, Inc.$26,054,235
- Martin Friedlander · Scripps Research Institute$17,515,314
- Celia A. Schiffer · Univ Of Massachusetts Med Sch Worcester$17,146,142
- J. Edwin Blalock · University Of Alabama At Birmingham$15,690,917
- Athan Kuliopulos · Tufts Medical Center$14,991,440
Research focus
Peptide HydrolasesComplexCellsBiologyEnzymesProteinsStructureDesignLibrariesBaseProtease InhibitorRecombinantsTechnologyPeptidesInhibitor/AntagonistChemistryMolecular ConformationViralCrystallizationLabelSuccessInterestDetectionBinding (Molecular Function)
Grant awards (114)
Maximizing tumor responses to targeted radiotherapy with a conditionally activated membrane binding probe$669,794
R01 · FY2025 · CA
Precision targeting of T cell cytotoxicity with PET$643,445
R01 · FY2025 · CA
Molecular Oncology Program$187,495
P30 · FY2025 · CA · contact PI
New radiotracer development to study immune cell mobilization of granzyme proteolytic activity$743,029
R01 · FY2024 · AI
Maximizing tumor responses to targeted radiotherapy with a conditionally activated membrane binding probe$616,174
R01 · FY2024 · CA
Precision targeting of T cell cytotoxicity with PET$611,272
R01 · FY2024 · CA
Probing the Role of Chaperone-TPR Complexes in Tau Proteostasis$568,644
R01 · FY2024 · AG
Molecular Oncology Program$185,205
P30 · FY2024 · CA · contact PI
New radiotracer development to study immune cell mobilization of granzyme proteolytic activity$660,398
R01 · FY2023 · AI
Precision targeting of T cell cytotoxicity with PET$635,683
R01 · FY2023 · CA
Developing Antivirals Targeting Proteases and Polymerases of Coronaviruses, Picornaviruses and Bunyavirales$5,168,269
U19 · FY2022 · AI · contact PI
New radiotracer development to study immune cell mobilization of granzyme proteolytic activity$740,394
R01 · FY2022 · AI
Precision targeting of T cell cytotoxicity with PET$652,933
R01 · FY2022 · CA
New radiotracer development to study immune cell mobilization of granzyme proteolytic activity$676,766
R01 · FY2021 · AI
Research Training in Chemistry and Chemical Biology$544,331
T32 · FY2021 · GM · contact PI
Precision targeting of T cell cytotoxicity with PET$524,205
R01 · FY2021 · CA
Application and Development of Antibody Tools$318,152
P50 · FY2021 · AI · contact PI
Probing the Role of Chaperone-TPR Complexes in Tau Proteostasis$2,240,412
RF1 · FY2020 · AG
Research Training in Chemistry and Chemical Biology$537,643
T32 · FY2020 · GM · contact PI
Application and Development of Antibody Tools$323,828
P50 · FY2020 · AI · contact PI
Research Training in Chemistry and Chemical Biology$531,111
T32 · FY2019 · GM · contact PI
Application and Development of Antibody Tools$318,673
P50 · FY2019 · AI · contact PI
Mapping the Conformational Cycle of Transmembrane Transporters pp 243-304$263,506
P01 · FY2019 · GM · contact PI
Antibody Generation pp197-242$158,502
P01 · FY2019 · GM · contact PI
Research Training in Chemistry and Chemical Biology$524,735
T32 · FY2018 · GM · contact PI
Antibodies for Characterizing the Structure and Function of Proteases$334,084
P41 · FY2018 · CA · contact PI
Application and Development of Antibody Tools$320,952
P50 · FY2018 · GM · contact PI
Mapping the Conformational Cycle of Transmembrane Transporters pp 243-304$263,506
P01 · FY2018 · GM · contact PI
Antibody Generation pp197-242$158,502
P01 · FY2018 · GM · contact PI
Research Training in Chemistry and Chemical Biology$432,091
T32 · FY2017 · GM · contact PI
Antibodies for Characterizing the Structure and Function of Proteases$339,541
P41 · FY2017 · CA · contact PI
Application and Development of Antibody Tools$319,940
P50 · FY2017 · GM · contact PI
Mapping the Conformational Cycle of Transmembrane Transporters pp 243-304$263,506
P01 · FY2017 · GM · contact PI
Antibody Generation pp197-242$158,502
P01 · FY2017 · GM · contact PI
Research Training in Chemistry and Chemical Biology$438,729
T32 · FY2016 · GM · contact PI
Antibodies for Characterizing the Structure and Function of Proteases$345,046
P41 · FY2016 · CA · contact PI
Allosteric Inhibition of a Family of Proteolytic Enzymes$306,698
R01 · FY2016 · GM · contact PI
HARC Center: HIV Accessory and Regulatory Complexes$273,656
P50 · FY2016 · GM · contact PI
Mapping the Conformational Cycle of Transmembrane Transporters pp 243-304$263,506
P01 · FY2016 · GM · contact PI
Non-invasive Differentiation of Benign Lesions from Aggressive Pancreatic Cancer$206,843
R21 · FY2016 · CA · contact PI
Antibody Generation pp197-242$158,502
P01 · FY2016 · GM · contact PI
Research Training in Chemistry and Chemical Biology$434,176
T32 · FY2015 · GM · contact PI
Antibodies for Characterizing the Structure and Function of Proteases$338,481
P41 · FY2015 · CA · contact PI
Allosteric Inhibition of a Family of Proteolytic Enzymes$306,456
R01 · FY2015 · GM · contact PI
HARC Center: HIV Accessory and Regulatory Complexes$284,756
P50 · FY2015 · GM · contact PI
Mapping the Conformational Cycle of Transmembrane Transporters pp 243-304$263,506
P01 · FY2015 · GM · contact PI
Antibody Generation pp197-242$228,502
P01 · FY2015 · GM · contact PI
Non-invasive Differentiation of Benign Lesions from Aggressive Pancreatic Cancer$172,097
R21 · FY2015 · CA · contact PI
Extracellular Proteolysis as a Molecular Stratification Tool for Cancer$168,280
R21 · FY2015 · CA · contact PI
Research Training in Chemistry and Chemical Biology$386,443
T32 · FY2014 · GM · contact PI
Antibodies for Characterizing the Structure and Function of Proteases$342,556
P41 · FY2014 · CA · contact PI
Allosteric Inhibition of a Family of Proteolytic Enzymes$305,247
R01 · FY2014 · GM · contact PI
HARC Center: HIV Accessory and Regulatory Complexes$289,859
P50 · FY2014 · GM · contact PI
Extracellular Proteolysis as a Molecular Stratification Tool for Cancer$201,953
R21 · FY2014 · CA · contact PI
Research Training in Chemistry and Chemical Biology$382,127
T32 · FY2013 · GM · contact PI
Allosteric Inhibition of a Family of Proteolytic Enzymes$303,795
R01 · FY2013 · GM · contact PI
HARC Center: HIV Accessory and Regulatory Complexes$285,417
P50 · FY2013 · GM · contact PI
Research Training in Chemistry and Chemical Biology$424,588
T32 · FY2012 · GM · contact PI
HARC Center: HIV Accessory and Regulatory Complexes$298,805
P50 · FY2012 · GM · contact PI
Protein Expression and Mass Spectrometry$396,533
P50 · FY2011 · GM · contact PI
Research Training in Chemistry and Chemical Biology$368,430
T32 · FY2011 · GM · contact PI
A Technological Platform for the Identification of Serine Proteases in Cancer$341,460
R01 · FY2011 · CA · contact PI
CHARACTERIZATION COVALENT INHIBITORS OF SERINE, CYSTEINE & ASPARTYL PROTEINASE$59,755
P41 · FY2011 · RR · contact PI
Protein Expression and Mass Spectrometry$394,317
P50 · FY2010 · GM · contact PI
Research Training in Chemistry and Chemical Biology$365,964
T32 · FY2010 · GM · contact PI
A Technological Platform for the Identification of Serine Proteases in Cancer$354,726
R01 · FY2010 · CA · contact PI
CHARACTERIZATION COVALENT INHIBITORS OF SERINE, CYSTEINE & ASPARTYL PROTEINASE$68,302
P41 · FY2010 · RR · contact PI
A Technological Platform for the Identification of Serine Proteases in Cancer$446,112
R01 · FY2009 · CA · contact PI
Protein Expression and Mass Spectrometry$409,825
P50 · FY2009 · GM · contact PI
Research Training in Chemistry and Chemical Biology$363,761
T32 · FY2009 · GM · contact PI
Targeting Allosteric Studies to Modulate Protein Interactions and Function$335,946
R01 · FY2009 · AI · contact PI
CHARACTERIZATION COVALENT INHIBITORS OF SERINE, CYSTEINE & ASPARTYL PROTEINASE$10,869
P41 · FY2009 · RR · contact PI
TARGETTING CYSTEINE PROTEINASES OF THE SARS-ASSOCIATED CORONAVIRUS$8,911
P41 · FY2009 · RR · contact PI
Protein Expression and Mass Spectrometry$395,631
P50 · FY2008 · GM · contact PI
Research Training in Chemistry and Chemical Biology$361,558
T32 · FY2008 · GM · contact PI
Targeting Allosteric Studies to Modulate Protein Interactions and Function$360,355
R01 · FY2008 · AI · contact PI
MOLECULAR BIOLOGY AND RECOMBINANT PROTEIN$146,912
P01 · FY2008 · AI · contact PI
CHARACTER COVALENT INHIBITORS OF SERINE, CYSTEINE & ASPARTYL PROTEINASE: HIV$15,071
P41 · FY2008 · RR · contact PI
TARGETTING CYSTEINE PROTEINASES OF THE SARS-ASSOCIATED CORONAVIRUS$5,792
P41 · FY2008 · RR · contact PI
Protein Expression and Mass Spectrometry$414,933
P50 · FY2007 · GM · contact PI
Research Training in Chemistry and Chemical Biology$361,558
T32 · FY2007 · GM · contact PI
Targeting Allosteric Studies to Modulate Protein Interactions and Function$361,012
R01 · FY2007 · AI · contact PI
MOLECULAR BIOLOGY AND RECOMBINANT PROTEIN$145,299
P01 · FY2007 · AI · contact PI
TARGETTING CYSTEINE PROTEINASES OF THE SARS-ASSOCIATED CORONAVIRUS$8,926
P41 · FY2007 · RR · contact PI
CHARACTER COVALENT INHIBITORS OF SERINE, CYSTEINE & ASPARTYL PROTEINASE: HIV$250
P41 · FY2007 · RR · contact PI
RESEARCH TRAINING IN CHEMISTRY AND CHEMICAL BIOLOGY$289,798
T32 · FY2006 · GM · contact PI
MOLECULAR BIOLOGY AND RECOMBINANT PROTEIN$148,127
P01 · FY2006 · AI · contact PI
TARGETTING CYSTEINE PROTEINASES OF THE SARS-ASSOCIATED CORONAVIRUS$7,655
P41 · FY2006 · RR · contact PI
CHARACTERIZATION COVALENT INHIBITORS OF SERINE, CYSTEINE & ASPARTYL PROTEINASE$5,550
P41 · FY2006 · RR · contact PI
RESEARCH TRAINING IN CHEMISTRY AND CHEMICAL BIOLOGY$289,798
T32 · FY2005 · GM
MOLECULAR BIOLOGY AND RECOMBINANT PROTEIN$144,479
P01 · FY2005 · AI
CHARACTERIZATION COVALENT INHIBITORS OF SERINE, CYSTEINE &ASPARTYL PROTEINASE$9,511
P41 · FY2005 · RR
TARGETTING CYSTEINE PROTEINASES OF THE SARS-ASSOCIATED CORONAVIRUS$6,432
P41 · FY2005 · RR
REDESIGNING TRYPSIN VIA DIRECTED MUTAGENESIS$263
P41 · FY2005 · RR
RESEARCH TRAINING IN CHEMISTRY AND CHEMICAL BIOLOGY$289,798
T32 · FY2004 · GM
MOLECULAR BIOLOGY AND RECOMBINANT PROTEIN$127,059
P01 · FY2004 · AI
STUDY OF SPECIFICITY OF CYSTEINE PROTEASES USING LIBRARY$6,160
P41 · FY2004 · RR
TARGETING CYSTEINE PROTEINASES OF THE SARS CORONAVIRUS$5,972
P41 · FY2004 · RR
REDESIGNING TRYPSIN VIA DIRECTED MUTAGENESIS$1,785
P41 · FY2004 · RR
RESEARCH TRAINING IN CHEMISTRY AND CHEMICAL BIOLOGY$250,652
T32 · FY2003 · GM
RESEARCH TRAINING IN CHEMISTRY AND CHEMICAL BIOLOGY$234,996
T32 · FY2002 · GM
HIV and Kaposi's Sarcoma Proteases$0
P01 · FY2002 · GM
INHIBITORS FOR EPITHELIAL CANCER ASSOCIATED PROTEASES--STRUCTURE BASED DESIGN$0
P01 · FY2002 · CA
BIOCHEMICAL ANALYSIS OF PROTEASE SUBSTRATE SPECIFICITY BY PROTEIN ENGINEERING$0
P01 · FY2002 · AI
Pilot--Combinatorial approaches in development of PSMA inhibitors$0
U56 · FY2002 · CA
STRUCTURAL BIOLOGY &TARGETED DRUG DESIGN FOR AIDS$0
P41 · FY2002 · RR
DOMINANT NEGATIVE INHIBITORS OF HIV PROTEASE AND KS HERPES VIRUS PROTEASE$159,403
P01 · FY2001 · GM
STRUCTURAL BIOLOGY &TARGETED DRUG DESIGN FOR AIDS$0
P41 · FY2001 · RR
INHIBITORS FOR EPITHELIAL CANCER ASSOCIATED PROTEASES--STRUCTURE BASED DESIGN$0
P01 · FY2001 · CA
BIOCHEMICAL ANALYSIS OF PROTEASE SUBSTRATE SPECIFICITY BY PROTEIN ENGINEERING$0
P01 · FY2001 · AI
DOMINANT NEGATIVE INHIBITORS OF HIV PROTEASE AND KS HERPES VIRUS PROTEASE$270,826
P01 · FY2000 · GM
INHIBITORS FOR EPITHELIAL CANCER ASSOCIATED PROTEASES--STRUCTURE BASED DESIGN$210,545
P01 · FY2000 · CA
BIOCHEMICAL ANALYSIS OF PROTEASE SUBSTRATE SPECIFICITY BY PROTEIN ENGINEERING$111,736
P01 · FY2000 · AI
STRUCTURAL BIOLOGY &TARGETED DRUG DESIGN FOR AIDS$9,880
P41 · FY2000 · RR