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Daniel Ryland Southworth

University Of Michigan At Ann Arbor

$8,878,677
Attributed
$13,891,599
Total exposure
9
Grants
6
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $3.3M · FY201525
$5M$3.8M$2.5M$1.3M$0
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$13,891,599 · 9

By mechanism

R01$6,632,200 · 4
RF1$4,926,721 · 2
P01$2,332,678 · 3

Top collaborators

Most similar at University Of Michigan At Ann Arbor

Same institution · by research overlap

Others in their field

Top investigators on “Structure

Research focus

StructureComplexMolecular ConformationResolutionProteinsMutantCryoelectron MicroscopyAlzheimer&AposBiochemicalBindingMolecular ChaperonesS DiseaseCrosslinkBaseCellsPreventNeurodegenerative DisordersPublic HealthFilamentArchitectureLengthAmyloidProtein Protein InteractionInsight

Grant awards (28)

Structural characterization of tau conformational heterogeneity in Down syndrome$269,788
RF1 · FY2025 · NS · contact PI
Probing the Role of Chaperone-TPR Complexes in Tau Proteostasis$568,644
R01 · FY2024 · AG
Mechanisms of Protein Disaggregation and Turnover by AAA+ Chaperones$402,556
R01 · FY2024 · GM · contact PI
Project 3: Structural basis of amyloid formation and chaperone-mediated turnover$355,300
P01 · FY2024 · AG · contact PI
Mechanisms of Protein Disaggregation and Turnover by AAA+ Chaperones$52,218
R01 · FY2024 · GM · contact PI
Structural characterization of tau aggregation variability and maturity in isolated cell types of the brain$2,416,521
RF1 · FY2023 · NS · contact PI
Mechanisms of Protein Disaggregation and Turnover by AAA+ Chaperones$402,495
R01 · FY2023 · GM · contact PI
Project 3: Structural basis of amyloid formation and chaperone-mediated turnover$355,300
P01 · FY2023 · AG · contact PI
Mechanisms of Protein Disaggregation and Turnover by AAA+ Chaperones$125,326
R01 · FY2023 · GM · contact PI
Mechanisms of Protein Disaggregation and Turnover by AAA+ Chaperones$402,495
R01 · FY2022 · GM · contact PI
Project 3: Structural basis of amyloid formation and chaperone-mediated turnover$355,300
P01 · FY2022 · AG · contact PI
Mechanisms of Protein Disaggregation and Turnover by AAA+ Chaperones$73,108
R01 · FY2022 · GM · contact PI
Mechanisms of motor neuron toxicity in Kennedy disease$512,581
R01 · FY2021 · NS
Mechanisms of Protein Disaggregation and Turnover by AAA+ Chaperones$392,681
R01 · FY2021 · GM · contact PI
Project 3: Structural basis of amyloid formation and chaperone-mediated turnover$355,300
P01 · FY2021 · AG · contact PI
Probing the Role of Chaperone-TPR Complexes in Tau Proteostasis$2,240,412
RF1 · FY2020 · AG
Mechanisms of motor neuron toxicity in Kennedy disease$523,094
R01 · FY2020 · NS
Project 3: Structural basis of amyloid formation and chaperone-mediated turnover$355,117
P01 · FY2020 · AG · contact PI
Mechanisms of motor neuron toxicity in Kennedy disease$538,742
R01 · FY2019 · NS
Defining the conformational cycle of nitric oxide synthases$300,152
R01 · FY2019 · GM · contact PI
Project 2: Structural studies of prions$278,195
P01 · FY2019 · AG · contact PI
Mechanisms of motor neuron toxicity in Kennedy disease$532,999
R01 · FY2018 · NS
Defining the conformational cycle of nitric oxide synthases$301,961
R01 · FY2018 · GM · contact PI
Project 2: Structural studies of prions$278,166
P01 · FY2018 · AG · contact PI
Mechanisms of motor neuron toxicity in Kennedy disease$588,180
R01 · FY2017 · NS
Defining the conformational cycle of nitric oxide synthases$313,038
R01 · FY2017 · GM · contact PI
Defining the conformational cycle of nitric oxide synthases$300,889
R01 · FY2016 · GM · contact PI
Defining the conformational cycle of nitric oxide synthases$301,041
R01 · FY2015 · GM · contact PI