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David Lowell Mobley

University Of California-Irvine

$5,876,948
Attributed
$5,876,948
Total exposure
4
Grants
4
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants. They are the sole PI on all grants (the two match).

Funding over time

peak $928.1K · FY201225
$1M$750K$500K$250K$0
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$5,876,948 · 4

By mechanism

R01$4,012,794 · 2
R35$1,596,592 · 1
R15$267,562 · 1

Top collaborators

No co-investigators on record.

Most similar at University Of California-Irvine

Same institution · by research overlap

Others in their field

Top investigators on “Affinity

Research focus

AffinityDrug DiscoveryPharmacologic SubstanceFree EnergyBlindComputing MethodologiesProteinsFailureBaseInnovationBindingMolecularCostScreeningPharmaceutical PreparationsSmall MoleculeSamplingCommon TreatmentHealth BenefitRewardsAutomationLead OptimizationDockingDrug Industry

Grant awards (20)

Accelerating drug discovery via ML-guided iterative design and optimization$590,384
R35 · FY2025 · GM · contact PI
Accelerating drug discovery via ML-guided iterative design and optimization$590,384
R35 · FY2024 · GM · contact PI
Accelerating drug discovery via ML-guided iterative design and optimization$415,824
R35 · FY2023 · GM · contact PI
Computational alchemy for molecular design and optimization$334,546
R01 · FY2022 · GM · contact PI
Computational alchemy for molecular design and optimization$339,040
R01 · FY2021 · GM · contact PI
Advancing predictive physical modeling through focused development of model systems to drive new modeling innovations$282,354
R01 · FY2021 · GM · contact PI
Advancing predictive physical modeling through focused development of model systems to drive new modeling innovations$349,074
R01 · FY2020 · GM · contact PI
Computational alchemy for molecular design and optimization$343,481
R01 · FY2020 · GM · contact PI
Advancing predictive physical modeling through focused development of model systems to drive new modeling innovations$235,500
R01 · FY2020 · GM · contact PI
Advancing predictive physical modeling through focused development of model systems to drive new modeling innovations$278,369
R01 · FY2019 · GM · contact PI
Advancing predictive physical modeling through focused development of model systems to drive new modeling innovations$66,531
R01 · FY2019 · GM · contact PI
Advancing predictive physical modeling through focused development of model systems to drive new modeling innovations$318,815
R01 · FY2018 · GM · contact PI
Alchemical free energy methods for efficient drug lead optimization$276,866
R01 · FY2018 · GM · contact PI
Alchemical free energy methods for efficient drug lead optimization$11,972
R01 · FY2018 · GM · contact PI
Alchemical free energy methods for efficient drug lead optimization$277,811
R01 · FY2017 · GM · contact PI
Alchemical free energy methods for efficient drug lead optimization$278,702
R01 · FY2016 · GM · contact PI
Alchemical free energy methods for efficient drug lead optimization$59,856
R01 · FY2016 · GM · contact PI
Alchemical free energy methods for efficient drug lead optimization$279,542
R01 · FY2015 · GM · contact PI
Alchemical free energy methods for efficient drug lead optimization$280,335
R01 · FY2014 · GM · contact PI
Testing and improving alchemical techniques for predicting protein-ligand binding$267,562
R15 · FY2012 · GM · contact PI