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Erol Fikrig

Yale University

$57,005,638
Attributed
$65,018,599
Total exposure
31
Grants
26
Lead (contact PI)

Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.

Funding over time

peak $17.2M · FY200525
$20M$15M$10M$5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25

Funding mix

By agency

NIH$90,783,762 · 33

By mechanism

R01$26,572,783 · 9
U19$17,814,289 · 3
N01$13,952,849 · 2
P01$12,228,968 · 3
U01$6,550,082 · 1
R37$4,287,845 · 1

Most similar at Yale University

Same institution · by research overlap

Others in their field

Top investigators on “Infection

Research focus

InfectionPathogenProteinsImmune ResponseCellsImmuneIn VivoResponseTicksLyme DiseaseGene ExpressionVectorPreventVaccinesBorrelia BurgdorferiBaseLeadIn VitroMolecularPathway InteractionsBlack-Legged TickImmunizationBorreliaTransmission Process

Grant awards (126)

Ixodes scapularis Immuno-Developmental and Metabolic Signaling Pathways and Interference with Ticks and Tick-borne Pathogens$1,941,828
P01 · FY2025 · AI
A novel Lyme disease vaccine$1,296,192
R01 · FY2025 · AI · contact PI
Mosquito SAMSP1 and SAMSP2 influence the initial stage of Plasmodium infection of mice$784,517
R01 · FY2025 · AI · contact PI
Tick Immune-Developmental and Metabolic Pathways as Anti-Tick Vaccine Targets$516,500
P01 · FY2025 · AI · contact PI
Systematic identification of interactions between Lyme Borrelia and Ixodes scapularis$461,375
R21 · FY2025 · AI · contact PI
The mosquito salivary protein AgBR1 as vaccine candidate against Chikungunya$299,969
R41 · FY2025 · AI · contact PI
A novel therapeutic for Lyme arthritis based on a secretory leukocyte protease inhibitor$299,933
R41 · FY2025 · AI · contact PI
A Multivalent mRNA Vaccine to Prevent Transmission of Tick-bornePathogens$299,250
R41 · FY2025 · AI
A novel vaccine against mosquito-borne Zika virus based on mosquito salivary gland protein AgBR1$980,219
R42 · FY2024 · AI · contact PI
Mosquito SAMSP1 and SAMSP2 influence the initial stage of Plasmodium infection of mice$796,541
R01 · FY2024 · AI · contact PI
A novel Lyme disease vaccine$648,096
R01 · FY2024 · AI · contact PI
The mosquito salivary protein AgBR1 as vaccine candidate against Chikungunya$299,969
R41 · FY2024 · AI · contact PI
A novel therapeutic for Lyme arthritis based on a secretory leukocyte protease inhibitor$299,933
R41 · FY2024 · AI · contact PI
A Multivalent mRNA Vaccine to Prevent Transmission of Tick-bornePathogens$298,362
R41 · FY2024 · AI
A novel vaccine against mosquito-borne Zika virus based on mosquito salivary gland protein AgBR1$979,482
R42 · FY2023 · AI · contact PI
Mosquito SAMSP1 and SAMSP2 influence the initial stage of Plasmodium infection of mice$807,849
R01 · FY2023 · AI · contact PI
A novel Lyme disease vaccine$648,096
R01 · FY2023 · AI · contact PI
Circadian Rhythms and Innate Immune Response in Aging$463,406
R01 · FY2023 · AI · contact PI
Tick Immune Signaling, Microbiota, and Acquisition of Borrelia burgdorferi and Anaplasma phagocytophilum$1,537,478
P01 · FY2022 · AI
A novel vaccine against mosquito-borne Zika virus based on mosquito salivary gland protein AgBR1$988,360
R42 · FY2022 · AI · contact PI
Mosquito SAMSP1 and SAMSP2 influence the initial stage of Plasmodium infection of mice$819,466
R01 · FY2022 · AI · contact PI
A novel Lyme disease vaccine$648,095
R01 · FY2022 · AI · contact PI
Circadian Rhythms and Innate Immune Response in Aging$473,000
R01 · FY2022 · AI · contact PI
The role of NLRP6 and DHX15 in control of infection by RNA viruses$418,750
R01 · FY2022 · AI · contact PI
Tick Gut Immunome- Gut Microbiota Interactions in the Context of Tick-Borne Pathogens$386,250
P01 · FY2022 · AI · contact PI
Tick Immune Signaling, Microbiota, and Acquisition of Borrelia burgdorferi and Anaplasma phagocytophilum$1,537,478
P01 · FY2021 · AI
Mosquito SAMSP1 and SAMSP2 influence the initial stage of Plasmodium infection of mice$844,320
R01 · FY2021 · AI · contact PI
Circadian Rhythms and Innate Immune Response in Aging$484,348
R01 · FY2021 · AI · contact PI
Tick Gut Immunome- Gut Microbiota Interactions in the Context of Tick-Borne Pathogens$418,750
P01 · FY2021 · AI · contact PI
The role of NLRP6 and DHX15 in control of infection by RNA viruses$418,750
R01 · FY2021 · AI · contact PI
AgTRIO, a protein in mosquito saliva, influences Plasmodium sporozoite infection$209,375
R21 · FY2021 · AI · contact PI
Tick Immune Signaling, Microbiota, and Acquisition of Borrelia burgdorferi and Anaplasma phagocytophilum$1,537,478
P01 · FY2020 · AI
Circadian Rhythms and Innate Immune Response in Aging$493,559
R01 · FY2020 · AI · contact PI
The role of tick gut microbiota in Borrelia burgdorferi transmission to mice$418,750
R01 · FY2020 · AI · contact PI
The role of NLRP6 and DHX15 in control of infection by RNA viruses$418,750
R01 · FY2020 · AI · contact PI
Ixodes scapularis saliva proteins that elicit tick immunity$418,750
R56 · FY2020 · AI
Tick Gut Immunome- Gut Microbiota Interactions in the Context of Tick-Borne Pathogens$418,750
P01 · FY2020 · AI · contact PI
A novel vaccine against mosquito-borne Zika virus based on mosquito salivary gland protein AgBR1$294,338
R41 · FY2020 · AI · contact PI
Immunization with mosquito AgTRIO protein to prevent malaria$293,394
R41 · FY2020 · AI · contact PI
AgTRIO, a protein in mosquito saliva, influences Plasmodium sporozoite infection$251,250
R21 · FY2020 · AI · contact PI
Tick Immune Signaling, Microbiota, and Acquisition of Borrelia burgdorferi and Anaplasma phagocytophilum$1,537,478
P01 · FY2019 · AI
Circadian Rhythms and Innate Immune Response in Aging$502,500
R01 · FY2019 · AI · contact PI
The role of NLRP6 and DHX15 in control of infection by RNA viruses$418,750
R01 · FY2019 · AI · contact PI
The role of tick gut microbiota in Borrelia burgdorferi transmission to mice$412,000
R01 · FY2019 · AI · contact PI
Tick Gut Immunome- Gut Microbiota Interactions in the Context of Tick-Borne Pathogens$386,250
P01 · FY2019 · AI · contact PI
A novel vaccine against mosquito-borne Zika virus based on mosquito salivary gland protein AgBR1$299,888
R41 · FY2019 · AI · contact PI
Immunization with mosquito AgTRIO protein to prevent malaria$298,944
R41 · FY2019 · AI · contact PI
Tick Immune Signaling, Microbiota, and Acquisition of Borrelia burgdorferi and Anaplasma phagocytophilum$1,578,353
P01 · FY2018 · AI
Tick Gut Immunome- Gut Microbiota Interactions in the Context of Tick-Borne Pathogens$432,375
P01 · FY2018 · AI · contact PI
The role of NLRP6 and DHX15 in control of infection by RNA viruses$418,750
R01 · FY2018 · AI · contact PI
The role of tick gut microbiota in Borrelia burgdorferi transmission to mice$415,375
R01 · FY2018 · AI · contact PI
The role of tick gut microbiota in Borrelia burgdorferi transmission to mice$405,250
R01 · FY2017 · AI · contact PI
Zika studies: Impaired human innate immune cell function in the elderly and immunosuppressed$265,948
N01 · FY2016 · AI · contact PI
Tissue-specific Borrelia Gene Expression$416,250
R37 · FY2015 · AI · contact PI
Defining signatures for immune responsiveness by functional systems immunology$356,913
U19 · FY2015 · AI
Immune signatures of clinical responses to flavivirus infections$37,534
U19 · FY2015 · AI · contact PI
Defining signatures for immune responsiveness by functional systems immunology$2,834,344
U19 · FY2014 · AI
Tissue-specific Borrelia Gene Expression$416,250
R37 · FY2014 · AI · contact PI
Interactions Between Anaplasma Phagocytophilum and Ixodes Scapularis$409,613
R01 · FY2014 · AI · contact PI
Immune signatures of clinical responses to flavivirus infections$352,210
U19 · FY2014 · AI · contact PI
Defining signatures for immune responsiveness by functional systems immunology$2,761,712
U19 · FY2013 · AI
Tissue-specific Borrelia Gene Expression$490,981
R37 · FY2013 · AI · contact PI
Immune signatures of clinical responses to flavivirus infections$400,422
U19 · FY2013 · AI · contact PI
Interactions Between Anaplasma Phagocytophilum and Ixodes Scapularis$385,036
R01 · FY2013 · AI · contact PI
Defining signatures for immune responsiveness by functional systems immunology$2,837,004
U19 · FY2012 · AI
Immune signatures of clinical responses to flavivirus infections$446,928
U19 · FY2012 · AI · contact PI
Tissue-specific Borrelia Gene Expression$414,688
R37 · FY2012 · AI · contact PI
Interactions Between Anaplasma Phagocytophilum and Ixodes Scapularis$409,613
R01 · FY2012 · AI · contact PI
Borrelia burgdorferi interactions with Ixodes scapularis$392,434
R01 · FY2012 · AI · contact PI
Impaired human innate immune cell function in the elderly and immunosuppressed$12,439,964
N01 · FY2011 · AI · contact PI
Defining signatures for immune responsiveness by functional systems immunology$2,849,006
U19 · FY2011 · AI
Immune signatures of clinical responses to flavivirus infections$482,125
U19 · FY2011 · AI · contact PI
Tissue-specific Borrelia Gene Expression$413,750
R37 · FY2011 · AI · contact PI
Interactions Between Anaplasma Phagocytophilum and Ixodes Scapularis$409,613
R01 · FY2011 · AI · contact PI
Borrelia burgdorferi interactions with Ixodes scapularis$392,434
R01 · FY2011 · AI · contact PI
Training in Investigative Infectious Diseases$254,280
T32 · FY2011 · AI · contact PI
Defining signatures for immune responsiveness by functional systems immunology$4,456,091
U19 · FY2010 · AI
Immunotherapeutics for Treatment of Flavivirus Infection$1,333,412
U01 · FY2010 · AI · contact PI
Immune Function and Biodefense in Immunocrompromised Populations$1,246,937
N01 · FY2010 · AI · contact PI
Interactions Between Anaplasma Phagocytophilum and Ixodes Scapularis$413,750
R01 · FY2010 · AI · contact PI
Borrelia burgdorferi interactions with Ixodes scapularis$396,397
R01 · FY2010 · AI · contact PI
Tissue-specific Borrelia Gene Expression$357,579
R37 · FY2010 · AI · contact PI
CIRCADIAN REGULATION OF INNATE IMMUNE MECHANISMS OF VIRAL RECOGNITION$206,875
R21 · FY2010 · AI · contact PI
Immunotherapeutics for Treatment of Flavivirus Infection$1,286,788
U01 · FY2009 · AI · contact PI
Borrelia burgdorferi interactions with Ixodes scapularis$400,401
R01 · FY2009 · AI · contact PI
Tissue-specific Borrelia Gene Expression$361,191
R37 · FY2009 · AI · contact PI
Tissue-specific Borrelia Gene Expression$250,319
R37 · FY2009 · AI · contact PI
CIRCADIAN REGULATION OF INNATE IMMUNE MECHANISMS OF VIRAL RECOGNITION$248,250
R21 · FY2009 · AI · contact PI
Immunotherapeutics for Treatment of Flavivirus Infection$1,254,949
U01 · FY2008 · AI · contact PI
Immunopathogenesis of Human Granulocytic Anaplasmosis$413,750
R56 · FY2008 · AI · contact PI
Borrelia burgdorferi interactions with Ixodes scapularis$400,200
R01 · FY2008 · AI · contact PI
Tissue-specific Borrelia Gene Expression$361,191
R37 · FY2008 · AI · contact PI
Immunotherapeutics for Treatment of Flavivirus Infection$1,279,237
U01 · FY2007 · AI · contact PI
Tissue-specific Borrelia Gene Expression$396,896
R37 · FY2007 · AI · contact PI
Immunopathogenesis of Granulocytic Ehrlichiosis$387,569
R01 · FY2007 · AI · contact PI
BORRELIA BURGDORFERI INTERACTIONS WITH IXODES SCAPULARIS$384,379
R01 · FY2007 · AI · contact PI
Toll-like receptor responses to West Nile virus$310,055
R01 · FY2007 · AI · contact PI
Immunotherapeutics for Treatment of Flavivirus Infection$1,395,696
U01 · FY2006 · AI · contact PI
Tissue-specific Borrelia Gene Expression$408,750
R37 · FY2006 · AI · contact PI
BORRELIA BURGDORFERI INTERACTIONS WITH IXODES SCAPULARIS$399,144
R01 · FY2006 · AI · contact PI
Immunopathogenesis of Granulocytic Ehrlichiosis$399,144
R01 · FY2006 · AI · contact PI
Toll-like receptor responses to West Nile virus$319,316
R01 · FY2006 · AI · contact PI
BORRELIA BURGDORFERI INTERACTIONS WITH IXODES SCAPULARIS$408,750
R01 · FY2005 · AI
Immunopathogenesis of Granulocytic Ehrlichiosis$408,750
R01 · FY2005 · AI
Toll-like receptor responses to West Nile virus$327,000
R01 · FY2005 · AI
Tissue Specific Borrelia Gene Expession$327,000
R01 · FY2005 · AI
BORRELIA BURGDORFERI INTERACTIONS WITH IXODES SCAPULARIS$408,750
R01 · FY2004 · AI
Immunopathogenesis of Granulocytic Ehrlichiosis$408,750
R01 · FY2004 · AI
Toll-like receptor responses to West Nile virus$327,000
R01 · FY2004 · AI
Tissue Specific Borrelia Gene Expession$327,000
R01 · FY2004 · AI
CO-INFECTION WITH BORRELIA BURGDORFERI AND ANAPLASMA PH*$245,250
R21 · FY2004 · AI
Neutrophil gene expression induced by A. phagocytophila$245,250
R21 · FY2004 · AI
Immunopathogenesis of Granulocytic Ehrlichiosis$408,750
R01 · FY2003 · AI
BORRELIA BURGDORFERI INTERACTIONS WITH IXODES SCAPULARIS$408,750
R01 · FY2003 · AI
Tissue Specific Borrelia Gene Expession$327,000
R01 · FY2003 · AI
CO-INFECTION WITH B BURGDORFERI AND A PHAGOCYTOPHILA$245,250
R21 · FY2003 · AI
Neutrophil gene expression induced by A. phagocytophila$245,250
R21 · FY2003 · AI
Toll-like receptor responses to West Nile virus$109,001
R01 · FY2003 · AI
ARTHROPOD SPECIFIC BORRELIA BURGDORFERI GENE EXPRESSION$403,768
R01 · FY2002 · AI
Tissue Specific Borrelia Gene Expession$327,000
R01 · FY2002 · AI
IMMUNOPATHOGENESIS OF GRANULOCYTIC EHRLICHIOSIS$317,930
R01 · FY2002 · AI
ARTHROPOD SPECIFIC BORRELIA BURGDORFERI GENE EXPRESSION$378,735
R01 · FY2001 · AI
Tissue Specific Borrelia Gene Expession$310,650
R01 · FY2001 · AI
IMMUNOPATHOGENESIS OF GRANULOCYTIC EHRLICHIOSIS$308,671
R01 · FY2001 · AI
ARTHROPOD SPECIFIC BORRELIA BURGDORFERI GENE EXPRESSION$365,640
R01 · FY2000 · AI
IMMUNOPATHOGENESIS OF GRANULOCYTIC EHRLICHIOSIS$299,680
R01 · FY2000 · AI