← Leaderboards
Dario Aa Vignali
University Of Pittsburgh At Pittsburgh
$40,087,127
Attributed
$47,200,540
Total exposure
38
Grants
33
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $6.7M · FY2005–25$10M$7.5M$5M$2.5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$72,482,146 · 39
By mechanism
P01$36,434,353 · 17
R01$22,879,205 · 7
R35$4,516,979 · 1
T32$3,496,429 · 1
P50$2,018,327 · 2
R56$1,553,500 · 3
Top collaborators
- Roy A Mariuzza13 shared
- Creg J Workman7 shared
- John Orban6 shared
- Robert J Binder4 shared
Most similar at University Of Pittsburgh At Pittsburgh
Same institution · by research overlap
- Roy A Mariuzza$20,943,458
- Creg J Workman$1,700,753
- Nicole Mihalik$75,520
Others in their field
Top investigators on “Mediating”
- Bambra Strokes · Ppd Development Lp$526,656,217
- Lawrence Corey · Fred Hutchinson Cancer Center$493,822,581
- Barton F Haynes · Duke University$295,802,493
- Glenda E Gray · Wits Health Consortium (Pty), Ltd$286,700,869
- Margaret Juliana McElrath · Fred Hutchinson Cancer Center$176,977,598
- Dan H. Barouch · Fred Hutchinson Cancer Center$122,734,499
Research focus
MediatingReceptorT-LymphocyteCellsMalignant NeoplasmsAutoimmunityChronicRegulationPreventTumorMolecularLeadImmunityCell TypeAutoimmune DiseasesImmuneCell PhysiologyTumor ImmunityVirus DiseasesTherapeutic TargetCd4 Positive T LymphocytesRegulatory T-LymphocyteSitePrograms
Grant awards (132)
Synergies among inhibitory receptors in tolerance and disease$2,775,439
P01 · FY2025 · AI · contact PI
Regulatory T cells and the tumor microenvironment$921,907
R35 · FY2025 · CA · contact PI
Structure, Function and Mechanistic Analysis of LAG3$745,225
R01 · FY2025 · AI · contact PI
Project 2 - Modulation of Tumor-Induced Tolerance by Inhibitory Receptors$531,128
P01 · FY2025 · AI · contact PI
Project 1: Evaluating the synergy of LAG3 and PD-1 in melanoma patients$525,166
P50 · FY2025 · CA · contact PI
Cancer Immunology Training Program$469,393
T32 · FY2025 · CA · contact PI
Core B - Mutant Mouse Core$303,481
P01 · FY2025 · AI · contact PI
Core D - Recombinant Antibody Core$281,608
P01 · FY2025 · AI · contact PI
Core A - Administrative Core$145,741
P01 · FY2025 · AI · contact PI
Synergies among inhibitory receptors in tolerance, cancer & antiviral immunity$2,311,666
P01 · FY2024 · AI · contact PI
Regulatory T cells and the tumor microenvironment$854,385
R35 · FY2024 · CA · contact PI
Structure, Function and Mechanistic Analysis of LAG3$783,023
R01 · FY2024 · AI · contact PI
Core B - Mutant Mouse$502,728
P01 · FY2024 · AI · contact PI
Cancer Immunology Training Program$500,063
T32 · FY2024 · CA · contact PI
Project 2 - Modulation of Anti-Tumor Immunity by Inhibitory Receptors$416,279
P01 · FY2024 · AI · contact PI
Project 1: Evaluating the synergy of LAG3 and PD-1 in melanoma patients$381,600
P50 · FY2024 · CA · contact PI
Core A - Administrative Core$132,695
P01 · FY2024 · AI · contact PI
Synergies among inhibitory receptors in tolerance, cancer & antiviral immunity$2,311,666
P01 · FY2023 · AI · contact PI
Regulatory T cells and the tumor microenvironment$906,381
R35 · FY2023 · CA · contact PI
Structure, Function and Mechanistic Analysis of LAG3$711,977
R01 · FY2023 · AI · contact PI
Cancer Immunology Training Program$518,655
T32 · FY2023 · CA · contact PI
Core B - Mutant Mouse$473,902
P01 · FY2023 · AI · contact PI
Project 2 - Modulation of Anti-Tumor Immunity by Inhibitory Receptors$445,105
P01 · FY2023 · AI · contact PI
Project 1: Evaluating the synergy of LAG3 and PD-1 in melanoma patients$369,676
P50 · FY2023 · CA · contact PI
Core A - Administrative Core$132,695
P01 · FY2023 · AI · contact PI
Synergies among inhibitory receptors in tolerance, cancer & antiviral immunity$2,311,666
P01 · FY2022 · AI · contact PI
Regulatory T cells and the tumor microenvironment$906,382
R35 · FY2022 · CA · contact PI
Structure, Function and Mechanistic Analysis of LAG3$711,977
R01 · FY2022 · AI · contact PI
Core B - Mutant Mouse$475,910
P01 · FY2022 · AI · contact PI
Project 2 - Modulation of Anti-Tumor Immunity by Inhibitory Receptors$422,269
P01 · FY2022 · AI · contact PI
Project 1: Evaluating the synergy of LAG3 and PD-1 in melanoma patients$378,022
P50 · FY2022 · CA · contact PI
Cancer Immunology Training Program$347,342
T32 · FY2022 · CA · contact PI
Core A - Administrative Core$153,523
P01 · FY2022 · AI · contact PI
Synergies among inhibitory receptors in tolerance, cancer & antiviral immunity$2,296,071
P01 · FY2021 · AI · contact PI
Regulatory T cells and the tumor microenvironment$927,924
R35 · FY2021 · CA · contact PI
Structure, Function and Mechanistic Analysis of LAG3$711,977
R01 · FY2021 · AI · contact PI
Structure and Activation of a Multiprotein Signaling Complex$691,950
R01 · FY2021 · AI
Core B - Mutant Mouse$456,137
P01 · FY2021 · AI · contact PI
Project 2 - Modulation of Anti-Tumor Immunity by Inhibitory Receptors$406,094
P01 · FY2021 · AI · contact PI
Project 1: Evaluating the synergy of LAG3 and PD-1 in melanoma patients$363,863
P50 · FY2021 · CA · contact PI
Core A - Administrative Core$173,876
P01 · FY2021 · AI · contact PI
FASEB's The Autoimmunity Conference$10,000
R13 · FY2021 · AI · contact PI
Synergies among inhibitory receptors in tolerance, cancer & antiviral immunity$2,353,012
P01 · FY2020 · AI · contact PI
Structure, Function and Mechanistic Analysis of LAG3$711,977
R01 · FY2020 · AI · contact PI
Structure and Activation of a Multiprotein Signaling Complex$692,071
R01 · FY2020 · AI
Core B - Mutant Mouse$458,455
P01 · FY2020 · AI · contact PI
Project 2 - Modulation of Anti-Tumor Immunity by Inhibitory Receptors$401,814
P01 · FY2020 · AI · contact PI
Interleukin-35 and the tumor microenvironment$395,781
R01 · FY2020 · CA · contact PI
Parameters that Underlie Treg Insufficiency in Autoimmune Diabetes$387,436
R01 · FY2020 · DK · contact PI
Cancer Immunology Training Program$349,571
T32 · FY2020 · CA · contact PI
Core A - Administrative Core$176,279
P01 · FY2020 · AI · contact PI
Synergies among inhibitory receptors in tolerance, cancer and antiviral immunity$2,188,670
P01 · FY2019 · AI · contact PI
Structure, Function and Mechanistic Analysis of LAG3$726,102
R01 · FY2019 · AI · contact PI
Structure and Activation of a Multiprotein Signaling Complex$701,777
R01 · FY2019 · AI
Modulation of Anti-Tumor Immunity by Inhibitory Receptors$416,987
P01 · FY2019 · AI · contact PI
Mouse Core$392,993
P01 · FY2019 · AI · contact PI
Parameters that Underlie Treg Insufficiency in Autoimmune Diabetes$387,436
R01 · FY2019 · DK · contact PI
Interleukin-35 and the tumor microenvironment$379,567
R01 · FY2019 · CA · contact PI
Cancer Immunology Training Program$193,532
T32 · FY2019 · CA · contact PI
Administrative Core$181,200
P01 · FY2019 · AI · contact PI
Cancer Immunology Program (Project-003)$34,500
P30 · FY2019 · CA · contact PI
Synergies among inhibitory receptors in tolerance, cancer and antiviral immunity$2,178,406
P01 · FY2018 · AI · contact PI
Structure and Activation of a Multiprotein Signaling Complex$694,073
R01 · FY2018 · AI
Modulation of Anti-Tumor Immunity by Inhibitory Receptors$412,140
P01 · FY2018 · AI · contact PI
Mouse Core$387,147
P01 · FY2018 · AI · contact PI
Interleukin-35 and the tumor microenvironment$386,962
R01 · FY2018 · CA · contact PI
Parameters that Underlie Treg Insufficiency in Autoimmune Diabetes$386,220
R01 · FY2018 · DK · contact PI
Cancer Immunology Training Program$302,625
T32 · FY2018 · CA · contact PI
Administrative Core$180,123
P01 · FY2018 · AI · contact PI
Synergies among inhibitory receptors in tolerance, cancer and antiviral immunity$2,170,094
P01 · FY2017 · AI · contact PI
Structure and Activation of a Multiprotein Signaling Complex$711,031
R01 · FY2017 · AI
Cancer Immunology Training Program$480,137
T32 · FY2017 · CA · contact PI
Modulation of Anti-Tumor Immunity by Inhibitory Receptors$407,472
P01 · FY2017 · AI · contact PI
Parameters that Underlie Treg Insufficiency in Autoimmune Diabetes$383,180
R01 · FY2017 · DK · contact PI
Mouse Core$380,847
P01 · FY2017 · AI · contact PI
Interleukin-35 and the tumor microenvironment$380,292
R01 · FY2017 · CA · contact PI
Administrative Core$179,154
P01 · FY2017 · AI · contact PI
Cancer Immunology Training Program$3,754
T32 · FY2017 · CA · contact PI
Synergies among inhibitory receptors in tolerance, cancer and antiviral immunity$2,161,524
P01 · FY2016 · AI · contact PI
Structural Analysis of the TCR-CD3 Complex and TCR Signaling$700,370
R56 · FY2016 · AI
Modulation of Anti-Tumor Immunity by Inhibitory Receptors$383,814
P01 · FY2016 · AI · contact PI
Interleukin-35 and the tumor microenvironment$372,595
R01 · FY2016 · CA · contact PI
Mouse Core$358,190
P01 · FY2016 · AI · contact PI
Cancer Immunology Training Program$331,357
T32 · FY2016 · CA · contact PI
Administrative Core$229,985
P01 · FY2016 · AI · contact PI
Synergies among inhibitory receptors in tolerance, cancer and antiviral immunity$2,223,392
P01 · FY2015 · AI · contact PI
A Regulatory Triad: IL35, Tregs and iTr35$408,100
R01 · FY2015 · AI · contact PI
Molecular Control of TCR Signaling and Function$385,000
R01 · FY2015 · AI · contact PI
Modulation of Anti-Tumor Immunity by Inhibitory Receptors$310,727
P01 · FY2015 · AI · contact PI
Mouse Core$302,219
P01 · FY2015 · AI · contact PI
Administrative Core$140,030
P01 · FY2015 · AI · contact PI
Molecular Control of TCR Signaling and Function$340,619
R01 · FY2014 · AI · contact PI
Parameters that influence CD4+ T cell diabetogenic potential$327,250
R01 · FY2014 · DK · contact PI
A Regulatory Triad: IL35, Tregs and iTr35$255,072
R01 · FY2014 · AI · contact PI
A Regulatory Triad: IL35, Tregs and iTr35$137,110
R01 · FY2014 · AI · contact PI
Molecular Control of TCR Signaling and Function$96,881
R01 · FY2014 · AI · contact PI
Molecular Control of TCR Signaling and Function$411,250
R01 · FY2013 · AI · contact PI
A Regulatory Triad: IL35, Tregs and iTr35$392,920
R01 · FY2013 · AI · contact PI
Parameters that influence CD4+ T cell diabetogenic potential$234,750
R01 · FY2013 · DK · contact PI
Molecular Control of TCR Signaling and Function$437,500
R01 · FY2012 · AI · contact PI
A Regulatory Triad: IL35, Tregs and iTr35$418,000
R01 · FY2012 · AI · contact PI
Parameters that influence CD4+ T cell diabetogenic potential$371,875
R01 · FY2012 · DK · contact PI
Tracking Cellular Migration In Vivo$262,500
R21 · FY2012 · AI · contact PI
Parameters that influence CD4+ T cell diabetogenic potential$437,500
R01 · FY2011 · DK · contact PI
A Regulatory Triad: IL35, Tregs and iTr35$435,000
R01 · FY2011 · AI · contact PI
Molecular Control of TCR Signaling and Function$434,896
R01 · FY2011 · AI · contact PI
Mechanism and function of the regulatory protein LAG-3$363,439
R01 · FY2011 · AI · contact PI
Tracking Cellular Migration In Vivo$217,448
R21 · FY2011 · AI · contact PI
Molecular Control of TCR Signaling and Function$435,000
R56 · FY2010 · AI · contact PI
Mechanism and function of the regulatory protein LAG-3$367,110
R01 · FY2010 · AI · contact PI
Mechanism and function of the regulatory protein LAG-3$504,000
R01 · FY2009 · AI · contact PI
Mechanism and function of the regulatory protein LAG-3$370,818
R01 · FY2009 · AI · contact PI
Control of CD4+ T cell Islet Entry and Diabetogenicity$418,130
R56 · FY2008 · AI · contact PI
Mechanism and function of the regulatory protein LAG-3$370,266
R01 · FY2008 · AI · contact PI
Mechanism and function of the regulatory protein LAG-3$370,688
R01 · FY2007 · AI · contact PI
Molecular Control of TCR Signaling and Function$355,568
R01 · FY2007 · AI · contact PI
QUESTIONS ABOUT THE TWO-HYBRID TECHNIQUE$8,298
P41 · FY2007 · RR · contact PI
DISSEMINATION PROJECT$6,224
P41 · FY2007 · RR · contact PI
Molecular Control of TCR Signaling and Function$366,188
R01 · FY2006 · AI · contact PI
Molecular Control of TCR Signaling and Function$375,000
R01 · FY2005 · AI
Multimolecular Interactions During TCR Recognition$262,500
R01 · FY2005 · AI
Molecular Control of TCR Signaling and Function$375,000
R01 · FY2004 · AI
Multimolecular Interactions During TCR Recognition$262,500
R01 · FY2004 · AI
Multimolecular Interactions During TCR Recognition$262,500
R01 · FY2003 · AI
Tolerance Induction by Targeted Expression of GAD$187,500
R21 · FY2003 · DK
Molecular Control of TCR Signaling and Function$187,500
R01 · FY2003 · AI
Molecular Control of TCR Signaling and Function$375,000
R21 · FY2002 · AI
Multimolecular Interactions During TCR Recognition$262,063
R01 · FY2002 · AI
Tolerance Induction by Targeted Expression of GAD$187,500
R21 · FY2002 · DK
Multimolecular Interactions During TCR Recognition$247,713
R01 · FY2001 · AI
Tolerance Induction by Targeted Expression of GAD$186,355
R21 · FY2001 · DK
MULTIMOLECULAR INTERACTIONS DURING TCR RECOGNITION$108,028
R29 · FY2000 · AI