← Leaderboards
Roy A Mariuzza
University Of Pittsburgh At Pittsburgh
$20,943,458
Attributed
$38,947,856
Total exposure
28
Grants
16
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $2.6M · FY2005–25$5M$3.8M$2.5M$1.3M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$38,947,856 · 28
By mechanism
R01$32,360,836 · 10
R37$3,213,846 · 1
R21$2,482,154 · 6
R56$700,370 · 1
R03$151,000 · 2
P41$39,650 · 8
Top collaborators
- Brian G. Pierce14 shared
- Dario Aa Vignali13 shared
- Alexander Andrianov10 shared
- Thomas R Fuerst10 shared
- John Orban10 shared
- Steven Foung7 shared
- Creg J Workman7 shared
- Gilad A Ofek5 shared
Others in their field
Top investigators on “Structure”
- David Heimbrook · Leidos Biomedical Research, Inc.$475,333,582
- Barton F Haynes · Duke University$444,977,767
- Lawrence Corey · Fred Hutchinson Cancer Center$334,646,086
- Gary D Acton · University Of California-Davis$320,373,312
- Mitchell J Malone · Texas A&M Research Foundation$320,373,312
- Michael David Hughes · Harvard University D/B/A Harvard School Of Public Health$315,257,203
Research focus
StructureComplexT-LymphocyteAffinityMediatingBaseLigandsReceptorMutantEpitopesMolecularBinding (Molecular Function)CellsReceptor BindingVariantSignal TransductionCrystallizationPeptidesImmune ResponseAntigensResponseSiteProteinsMutagenesis
Grant awards (96)
Rational design and efficacy testing of vaccines against HCV$1,357,012
R01 · FY2025 · AI
Structure, Function and Mechanistic Analysis of LAG3$745,225
R01 · FY2025 · AI
Rational design and efficacy testing of vaccines against HCV$1,410,043
R01 · FY2024 · AI
Structure, Function and Mechanistic Analysis of LAG3$783,023
R01 · FY2024 · AI
Structural Basis for T Cell Recognition of SARS-CoV-2$193,671
R21 · FY2024 · AI · contact PI
Rational design and efficacy testing of vaccines against HCV$179,958
R01 · FY2024 · AI
Rational design and efficacy testing of vaccines against HCV$1,379,680
R01 · FY2023 · AI
Structure, Function and Mechanistic Analysis of LAG3$711,977
R01 · FY2023 · AI
Structural Basis for T Cell Recognition of SARS-CoV-2$232,710
R21 · FY2023 · AI · contact PI
Rational design and efficacy testing of vaccines against HCV$1,410,544
R01 · FY2022 · AI
Structure, Function and Mechanistic Analysis of LAG3$711,977
R01 · FY2022 · AI
Structure-Based Vaccine Design for Hepatits C Virus$1,120,994
R01 · FY2021 · AI
Structure, Function and Mechanistic Analysis of LAG3$711,977
R01 · FY2021 · AI
Structure and Activation of a Multiprotein Signaling Complex$691,950
R01 · FY2021 · AI · contact PI
Structure-Based Vaccine Design for Hepatits C Virus$1,128,779
R01 · FY2020 · AI
Structure, Function and Mechanistic Analysis of LAG3$711,977
R01 · FY2020 · AI
Structure and Activation of a Multiprotein Signaling Complex$692,071
R01 · FY2020 · AI · contact PI
Structure-Based Vaccine Design for Hepatits C Virus$1,136,335
R01 · FY2019 · AI
Structure, Function and Mechanistic Analysis of LAG3$726,102
R01 · FY2019 · AI
Structure and Activation of a Multiprotein Signaling Complex$701,777
R01 · FY2019 · AI · contact PI
Structure-Based Vaccine Design for Hepatits C Virus$1,142,860
R01 · FY2018 · AI
Structure and Activation of a Multiprotein Signaling Complex$694,073
R01 · FY2018 · AI · contact PI
Structure-Based Vaccine Design for Hepatits C Virus$1,449,630
R01 · FY2017 · AI
Structure and Activation of a Multiprotein Signaling Complex$711,031
R01 · FY2017 · AI · contact PI
Structure-based HCV vaccine design$193,150
R21 · FY2017 · AI
Structural Analysis of the TCR-CD3 Complex and TCR Signaling$700,370
R56 · FY2016 · AI · contact PI
Structure-based HCV vaccine design$246,400
R21 · FY2016 · AI
Structure and Function of T Cell Antigen Receptors$371,250
R01 · FY2014 · AI · contact PI
Structure and Function of Natural Killer Cell Receptors$334,125
R01 · FY2014 · AI · contact PI
Structural Analysis of the TCR-CD3 Receptor Complex$190,000
R21 · FY2014 · AI · contact PI
Structure and Function of T Cell Antigen Receptors$348,975
R01 · FY2013 · AI · contact PI
Structure and Function of Natural Killer Cell Receptors$314,078
R01 · FY2013 · AI · contact PI
Structural Analysis of the TCR-CD3 Receptor Complex$228,000
R21 · FY2013 · AI · contact PI
Solution structure and dynamics of TCR in free and peptide-MHC-bound states$190,000
R21 · FY2013 · AI
Recognition of Self and Mutated Self by Autoimmune and Tumor-Specific TCRs$384,690
R01 · FY2012 · AI · contact PI
Structure and Function of T Cell Antigen Receptors$371,250
R01 · FY2012 · AI · contact PI
Structure and Function of Natural Killer Cell Receptors$334,125
R01 · FY2012 · AI · contact PI
Solution structure and dynamics of TCR in free and peptide-MHC-bound states$228,000
R21 · FY2012 · AI
Recognition of Self and Mutated Self by Autoimmune and Tumor-Specific TCRs$384,690
R01 · FY2011 · AI · contact PI
Structure and Function of T Cell Antigen Receptors$371,250
R01 · FY2011 · AI · contact PI
Structure and Function of Natural Killer Cell Receptors$334,125
R01 · FY2011 · AI · contact PI
CRYSTAL STRUCTURES OF TCR AND MHC AND CD4 COMPLEX$2,300
P41 · FY2011 · RR · contact PI
Recognition of Self and Mutated Self by Autoimmune and Tumor-Specific TCRs$388,575
R01 · FY2010 · AI · contact PI
Structure and Function of T Cell Antigen Receptors$375,000
R01 · FY2010 · AI · contact PI
Structure and Function of Natural Killer Cell Receptors$337,500
R01 · FY2010 · AI · contact PI
Recombinant Antibodies from the Sea Lamprey$187,500
R21 · FY2010 · AI
Recognition of Self and Mutated Self by Autoimmune and Tumor-Specific TCRs$392,500
R01 · FY2009 · AI · contact PI
STRUCTURE AND FUNCTION OF T CELL ANTIGEN RECEPTORS$310,793
R37 · FY2009 · AI · contact PI
Microbial Recognition by Innate Immune Receptors$276,259
R01 · FY2009 · AI · contact PI
Recombinant Antibodies from the Sea Lamprey$225,000
R21 · FY2009 · AI
STRUCT BAS FOR PEPTIDOGLYCAN RECOGNITION BY HUMAN PEPTIDOGLYCAN RECOGNITION$11,653
P41 · FY2009 · RR · contact PI
Recognition of Self and Mutated Self by Autoimmune and Tumor-Specific TCRs$405,000
R01 · FY2008 · AI · contact PI
STRUCTURE AND FUNCTION OF T CELL ANTIGEN RECEPTORS$310,793
R37 · FY2008 · AI · contact PI
Microbial Recognition by Innate Immune Receptors$276,259
R01 · FY2008 · AI · contact PI
Structure and Function of Natural Killer Cell Receptors$276,259
R01 · FY2008 · AI · contact PI
Development of MHC-Based Therapeutics for Superantigen-Induced Toxic Shock$182,098
R21 · FY2008 · AI · contact PI
Structure and Function of Natural Killer Cell Receptors$47,390
R03 · FY2008 · TW · contact PI
COMPLEX OF PHOSPHOLIPASE C GAMMA1, GADS AND AN SLP-76 MOTIF$3,961
P41 · FY2008 · RR · contact PI
STRUCTURE AND FUNCTION OF T CELL ANTIGEN RECEPTORS$316,811
R37 · FY2007 · AI · contact PI
Microbial Recognition by Innate Immune Receptors$281,609
R01 · FY2007 · AI · contact PI
Structure and Function of Natural Killer Cell Receptors$281,609
R01 · FY2007 · AI · contact PI
Development of MHC-Based Therapeutics for Superantigen-Induced Toxic Shock$185,625
R21 · FY2007 · AI · contact PI
Structure and Function of Natural Killer Cell Receptors$29,610
R03 · FY2007 · TW · contact PI
COMPLEX OF PHOSPHOLIPASE C GAMMA1, GADS AND AN SLP-76 MOTIF$3,130
P41 · FY2007 · RR · contact PI
STRUCTURE AND FUNCTION OF T CELL ANTIGEN RECEPTORS$326,274
R37 · FY2006 · AI · contact PI
Microbial Recognition by Innate Immune Receptors$290,021
R01 · FY2006 · AI · contact PI
Structural and Function of Natural Killer Cell Receptors$290,021
R01 · FY2006 · AI · contact PI
CRYSTAL STRUCTURE OF THE NATURAL KILLER CELL RECEPTOR 2B4 IN COMPLEX WITH CD48$2,390
P41 · FY2006 · RR · contact PI
STRUCTURE AND FUNCTION OF T CELL ANTIGEN RECEPTORS$334,125
R37 · FY2005 · AI
Structural and Function of Natural Killer Cell Receptors$297,000
R01 · FY2005 · AI
Physical Basis of T Cell Activation by Superantigens$259,000
R01 · FY2005 · AI
Microbial Recognition by Innate Immune Receptors$252,450
R01 · FY2005 · AI
Structure-Function Study of Protein-Protein Recognition$94,050
R01 · FY2005 · GM
STRUCTURE AND FUNCTION OF T CELL ANTIGEN RECEPTORS$333,000
R37 · FY2004 · AI
Structure and Function of Natural Killer Cell Receptors$297,000
R01 · FY2004 · AI
Structure-Function Study of Protein-Protein Recognition$281,200
R01 · FY2004 · GM
Physical Basis of T Cell Activation by Superantigens$259,000
R01 · FY2004 · AI
STRUCTURAL BASIS FOR RECOGNITION OF THE LINKER$7,178
P41 · FY2004 · RR
STRUCTURE OF HUMAN PEPTIDOGLYCAN RECOGNITION PROTEINS$5,842
P41 · FY2004 · RR
STRUCTURE OF HUMAN PEPTIDOGLYCAN RECOGNITION PROTEINS$3,196
P41 · FY2004 · RR
STRUCTURE AND FUNCTION OF T CELL ANTIGEN RECEPTORS$333,000
R37 · FY2003 · AI
Structure-Function Study of Protein-Protein Recognition$281,197
R01 · FY2003 · GM
Physical Basis of T Cell Activation by Superantigens$259,000
R01 · FY2003 · AI
STRUCTURE AND FUNCTION OF NATURAL KILLER CELL RECEPTORS$259,000
R01 · FY2003 · AI
STRUCTURE AND FUNCTION OF T CELL ANTIGEN RECEPTORS$283,050
R37 · FY2002 · AI
Structure-Function Study of Protein-Protein Recognition$281,200
R01 · FY2002 · GM
Physical Basis of T Cell Activation by Superantigens$259,000
R01 · FY2002 · AI
STRUCTURE AND FUNCTION OF NATURAL KILLER CELL RECEPTORS$259,000
R01 · FY2002 · AI
STRUCTURE AND FUNCTION OF T CELL ANTIGEN RECEPTORS$333,000
R37 · FY2001 · AI
Structure-Function Study of Protein-Protein Recognition$281,200
R01 · FY2001 · GM
STRUCTURE AND FUNCTION OF NATURAL KILLER CELL RECEPTORS$259,000
R01 · FY2001 · AI
Physical Basis of T Cell Activation by Superantigens$259,000
R01 · FY2001 · AI
STRUCTURE AND FUNCTION OF T CELL ANTIGEN RECEPTORS$333,000
R37 · FY2000 · AI
STRUCTURE AND FUNCTION OF NATURAL KILLER CELL RECEPTORS$259,000
R01 · FY2000 · AI
STRUCTURE/FUNCTION STUDIES OF ANTIGEN-ANTIBODY REACTIONS$236,374
R01 · FY2000 · GM
PHYSICAL BASIS OF T CELL ACTIVATION BY SUPERANTIGENS$74,000
R03 · FY2000 · AI