← Leaderboards
Alain Charest
Tufts Medical Center
$13,040,812
Attributed
$28,838,808
Total exposure
16
Grants
9
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $4.7M · FY2009–25$5M$3.8M$2.5M$1.3M$0
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$37,465,050 · 17
By mechanism
U19$16,702,484 · 5
R01$11,333,227 · 5
U01$3,301,199 · 1
UH3$2,099,368 · 1
P01$2,056,707 · 2
UG3$1,049,972 · 1
Top collaborators
- Xandra Owens Breakefield29 shared
- Stephen J Gould29 shared
- Anna M. Krichevsky29 shared
- Thorsten Roman Mempel29 shared
- Vassiliki A Boussiotis11 shared
- Robert J Coffey4 shared
- Steven P Gygi4 shared
- Franziska Michor4 shared
Others in their field
Top investigators on “Glioblastoma”
- David Heimbrook · Leidos Biomedical Research, Inc.$50,454,235
- John H Sampson · Duke University$34,869,540
- Walter John Curran · Thomas Jefferson University$27,327,059
- Jann N Sarkaria · Mayo Clinic Coll Of Medicine, Rochester$23,947,143
- Jeremy N Rich · University Of Pittsburgh At Pittsburgh$21,935,828
- Maciej S Lesniak · Northwestern University$18,837,339
Research focus
GlioblastomaMouse ModelTumorNeoplastic CellCellsEpidermal Growth Factor ReceptorMolecularMalignant NeoplasmsMediatingIn VivoMalignant Neoplasm Of BrainGenetically Engineered MouseReagentGeneticSamplingExtracellularGliomaAnimalsBrainGenomicsMicrogliaMonitorBiologyProduction
Grant awards (69)
Dissecting Orchestrated Immune Responses to Glioblastoma within the Native Tissue Microenvironment to Improve Treatment Outcomes$687,279
R01 · FY2025 · NS · contact PI
Understanding the cellular and functional changes in the immune tumor microenvironment of glioblastoma during progression and treatments.$648,380
R01 · FY2025 · CA · contact PI
Engineering T Cell Adoptive Therapy for Glioblastoma$642,482
R01 · FY2025 · NS
Engineering T Cell Adoptive Therapy for Glioblastoma$624,543
R01 · FY2024 · NS
Understanding the cellular and functional changes in the immune tumor microenvironment of glioblastoma during progression and treatments.$618,825
R01 · FY2024 · CA · contact PI
Deciphering TREM1/2 Function in Primary Brain Cancer Using a New Model of Glioblastoma$472,124
R21 · FY2024 · NS · contact PI
Understanding the cellular and functional changes in the immune tumor microenvironment of glioblastoma during progression and treatments.$672,634
R01 · FY2023 · CA · contact PI
Engineering T Cell Adoptive Therapy for Glioblastoma$658,407
R01 · FY2023 · NS
Uncovering exRNA and protein determinants of secreted vesicle heterogeneity by flow cytometric purification of vesicle subsets from cells and plasma$1,049,684
UH3 · FY2022 · CA
Advancing treatment outcomes in malignant glioma by integrating immunotherapy and standard of care using genetically engineered mice that recapitulate molecular feature of human glioma$635,966
R01 · FY2022 · CA · contact PI
Advancing treatment outcomes in malignant glioma by integrating immunotherapy and standard of care using genetically engineered mice that recapitulate molecular feature of human glioma$44,396
R01 · FY2022 · CA · contact PI
Uncovering exRNA and protein determinants of secreted vesicle heterogeneity by flow cytometric purification of vesicle subsets from cells and plasma$1,049,684
UH3 · FY2021 · CA
Advancing treatment outcomes in malignant glioma by integrating immunotherapy and standard of care using genetically engineered mice that recapitulate molecular feature of human glioma$648,944
R01 · FY2021 · CA · contact PI
Therapeutic vulnerabilities associated with PTEN missense mutations$204,531
R21 · FY2021 · CA · contact PI
Core C Mouse Model Core$148,410
P01 · FY2021 · CA · contact PI
Advancing Treatment Outcomes in Malignant Glioma by Integrating Immunotherapy and Standard of Care using Genetically Engineered Mice that Recapitulate Molecular Feature of Human Glioma$45,302
R01 · FY2021 · CA · contact PI
Advancing treatment outcomes in malignant glioma by integrating immunotherapy and standard of care using genetically engineered mice that recapitulate molecular feature of human glioma$648,944
R01 · FY2020 · CA · contact PI
Uncovering exRNA and protein determinants of secreted vesicle heterogeneity by flow cytometric purification of vesicle subsets from cells and plasma$516,236
UG3 · FY2020 · CA
Therapeutic vulnerabilities associated with PTEN missense mutations$245,438
R21 · FY2020 · CA · contact PI
Core C Mouse Model Core$148,410
P01 · FY2020 · CA · contact PI
Advancing treatment outcomes in malignant glioma by integrating immunotherapy and standard of care using genetically engineered mice that recapitulate molecular feature of human glioma$629,475
R01 · FY2019 · CA · contact PI
Uncovering exRNA and protein determinants of secreted vesicle heterogeneity by flow cytometric purification of vesicle subsets from cells and plasma$533,736
UG3 · FY2019 · CA
Core C Mouse Model Core$188,379
P01 · FY2019 · CA · contact PI
Advancing treatment outcomes in malignant glioma by integrating immunotherapy and standard of care using genetically engineered mice that recapitulate molecular feature of human glioma$667,694
R01 · FY2018 · CA · contact PI
Core C Mouse Model Core$148,410
P01 · FY2018 · CA · contact PI
exRNA released by glioblastoma alters brain microenvironment$1,636,002
U19 · FY2017 · CA
(PQB5)Molecular Wiring and Therapeutic Targeting of EGFR and PDGFR Signaling Netw$882,372
R01 · FY2017 · CA · contact PI
Mouse models of glioma to study functional exRNA transfer to the microenvironmen$419,247
U19 · FY2017 · CA
Intravital Microscopy Core$415,173
U19 · FY2017 · CA
Transfer of microRNA regulators from glioblastoma to brain microenvironment$405,296
U19 · FY2017 · CA
Mechanisms of exRNA Trafficking$396,286
U19 · FY2017 · CA
Core C Mouse Model Core$166,160
P01 · FY2017 · CA · contact PI
exRNA released by glioblastoma alters brain microenvironment$25,000
U19 · FY2017 · CA
exRNA released by glioblastoma alters brain microenvironment$1,581,106
U19 · FY2016 · CA
(PQB5)Molecular Wiring and Therapeutic Targeting of EGFR and PDGFR Signaling Netw$918,872
R01 · FY2016 · CA · contact PI
Mouse models of glioma to study functional exRNA transfer to the microenvironmen$403,400
U19 · FY2016 · CA
Intravital Microscopy Core$399,454
U19 · FY2016 · CA
Transfer of microRNA regulators from glioblastoma to brain microenvironment$392,317
U19 · FY2016 · CA
Mechanisms of exRNA Trafficking$385,935
U19 · FY2016 · CA
exRNA released by glioblastoma alters brain microenvironment$338,000
U19 · FY2016 · CA
Genetically engineered mouse models$269,306
P01 · FY2016 · CA · contact PI
exRNA released by glioblastoma alters brain microenvironment$1,592,843
U19 · FY2015 · CA
(PQB5)Molecular Wiring and Therapeutic Targeting of EGFR and PDGFR Signaling Netw$813,106
R01 · FY2015 · CA · contact PI
Mouse models of glioma to study functional exRNA transfer to the microenvironmen$404,578
U19 · FY2015 · CA
Intravital Microscopy Core$400,632
U19 · FY2015 · CA
Transfer of microRNA regulators from glioblastoma to brain microenvironment$395,879
U19 · FY2015 · CA
Mechanisms of exRNA Trafficking$391,754
U19 · FY2015 · CA
Genetically engineered mouse models$249,241
P01 · FY2015 · CA · contact PI
exRNA released by glioblastoma alters brain microenvironment$1,604,204
U19 · FY2014 · CA
(PQB5)Molecular Wiring and Therapeutic Targeting of EGFR and PDGFR Signaling Netw$845,606
R01 · FY2014 · CA · contact PI
Mouse models of glioma to study functional exRNA transfer to the microenvironmen$405,707
U19 · FY2014 · CA
Intravital Microscopy Core$401,761
U19 · FY2014 · CA
Transfer of microRNA regulators from glioblastoma to brain microenvironment$399,348
U19 · FY2014 · CA
Mechanisms of exRNA Trafficking$397,388
U19 · FY2014 · CA
Genetically engineered mouse models$249,154
P01 · FY2014 · CA · contact PI
exRNA released by glioblastoma alters brain microenvironment$100,000
U19 · FY2014 · CA
exRNA released by glioblastoma alters brain microenvironment$87,000
U19 · FY2014 · CA
exRNA released by glioblastoma alters brain microenvironment$1,662,087
U19 · FY2013 · CA
Understanding and Eliminating Oncogenic EGFR Signaling in Malignant Glioma$619,594
U01 · FY2013 · CA · contact PI
Mouse models of glioma to study functional exRNA transfer to the microenvironmen$418,480
U19 · FY2013 · CA
Transfer of microRNA regulators from glioblastoma to brain microenvironment$414,537
U19 · FY2013 · CA
Mechanisms of exRNA Trafficking$414,536
U19 · FY2013 · CA
Intravital Microscopy Core$414,534
U19 · FY2013 · CA
Genetically engineered mouse models$230,654
P01 · FY2013 · CA · contact PI
Understanding and Eliminating Oncogenic EGFR Signaling in Malignant Glioma$660,126
U01 · FY2012 · CA · contact PI
Genetically engineered mouse models$258,583
P01 · FY2012 · CA · contact PI
Understanding and Eliminating Oncogenic EGFR Signaling in Malignant Glioma$661,137
U01 · FY2011 · CA · contact PI
Understanding and Eliminating Oncogenic EGFR Signaling in Malignant Glioma$682,666
U01 · FY2010 · CA · contact PI
Understanding and Eliminating Oncogenic EGFR Signaling in Malignant Glioma$677,676
U01 · FY2009 · CA · contact PI