← Leaderboards
Xandra Owens Breakefield
Massachusetts General Hospital
$30,735,276
Attributed
$39,390,569
Total exposure
36
Grants
30
Lead (contact PI)
Attributed= this PI's even-split share of every grant they're on (the fair, additive number). Exposure = full size of all those grants.
Funding over time
peak $8.2M · FY2005–25$10M$7.5M$5M$2.5M$0
'05
'06
'07
'08
'09
'10
'11
'12
'13
'14
'15
'16
'17
'18
'19
'20
'21
'22
'23
'24
'25
Funding mix
By agency
NIH$103,930,630 · 43
By mechanism
P01$50,241,719 · 14
U19$16,702,484 · 5
P50$12,929,190 · 6
P30$8,802,231 · 6
R35$6,870,377 · 1
R01$5,214,134 · 3
Top collaborators
- Alain Charest29 shared
- Stephen J Gould29 shared
- Anna M. Krichevsky29 shared
- Thorsten Roman Mempel29 shared
- Bakhos A. Tannous20 shared
- E. Antonio Chiocca9 shared
- Laurie J. Ozelius5 shared
- Casey A Maguire3 shared
Most similar at Massachusetts General Hospital
Same institution · by research overlap
- Vijaya Ramesh$9,458,883
- Casey A Maguire$2,661,741
Others in their field
Top investigators on “Cells”
- Lawrence Corey · Fred Hutchinson Cancer Center$536,344,731
- Barton F Haynes · Duke University$457,457,619
- David Heimbrook · Leidos Biomedical Research, Inc.$454,789,509
- Glenda E Gray · Wits Health Consortium (Pty), Ltd$299,104,942
- Dennis R. Burton · Scripps Research Institute$278,781,854
- Mary M Horowitz · Medical College Of Wisconsin$237,383,608
Research focus
CellsBrainMonitorGlioblastomaTumorMouse ModelNeoplastic CellProgramsProteinsGliomaBrain NeoplasmsMalignant NeoplasmsMolecularGenesMediatingVectorMessenger RnaTumor GrowthResearch PersonnelPhenotypeIn VivoCollaborationsEvaluationResponse
Grant awards (200)
Immuno-Cell Therapy for Brain Tumors$544,859
R01 · FY2025 · NS · contact PI
The power of extracellular vesicles in glioblastoma$959,035
R35 · FY2024 · CA · contact PI
Immuno-Cell Therapy for Brain Tumors$571,443
R01 · FY2024 · NS · contact PI
The power of extracellular vesicles in glioblastoma$989,360
R35 · FY2023 · CA · contact PI
Immuno-Cell Therapy for Brain Tumors$596,913
R01 · FY2023 · NS · contact PI
The power of extracellular vesicles in glioblastoma$989,400
R35 · FY2022 · CA · contact PI
Gene therapy for Tuberous Sclerosis$420,000
R33 · FY2022 · NS · contact PI
Extracellular Vesicles (EVs) and Genes in the Biology and Therapy of Gliomas$1,316,194
P01 · FY2021 · CA · contact PI
The power of extracellular vesicles in glioblastoma$1,009,269
R35 · FY2021 · CA · contact PI
Project 1 Extracellular Vesicles (EVs) Role in GBM Pathobiology$284,382
P01 · FY2021 · CA · contact PI
Core A Administration$148,368
P01 · FY2021 · CA · contact PI
Extracellular Vesicles (EVs) and Genes in the Biology and Therapy of Gliomas$1,316,276
P01 · FY2020 · CA · contact PI
The power of extracellular vesicles in glioblastoma$1,009,233
R35 · FY2020 · CA · contact PI
Gene therapy for tuberous sclerosis$420,000
R61 · FY2020 · NS · contact PI
Project 1 Extracellular Vesicles (EVs) Role in GBM Pathobiology$284,348
P01 · FY2020 · CA · contact PI
Core A Administration$148,368
P01 · FY2020 · CA · contact PI
Extracellular Vesicles (EVs) and Genes in the Biology and Therapy of Gliomas$1,277,211
P01 · FY2019 · CA · contact PI
Molecular etiology of early onset dystonia$1,276,905
P01 · FY2019 · NS · contact PI
The power of extracellular vesicles in glioblastoma$979,009
R35 · FY2019 · CA · contact PI
Gene therapy for tuberous sclerosis$420,000
R61 · FY2019 · NS · contact PI
TorsinA as a key link in receptor-mediated signaling$296,642
P01 · FY2019 · NS · contact PI
Project 1 Extracellular Vesicles (EVs) Role in GBM Pathobiology$206,698
P01 · FY2019 · CA · contact PI
Core A Administration$143,307
P01 · FY2019 · CA · contact PI
Administration$103,224
P01 · FY2019 · NS · contact PI
Extracellular Vesicles (EVs) and Genes in the Biology and Therapy of Gliomas$1,316,832
P01 · FY2018 · CA · contact PI
Molecular etiology of early onset dystonia$1,276,977
P01 · FY2018 · NS · contact PI
The power of extracellular vesicles in glioblastoma$935,071
R35 · FY2018 · CA · contact PI
Interdepartmental Neuroscience Center$696,000
P30 · FY2018 · NS · contact PI
TorsinA as a key link in receptor-mediated signaling$296,712
P01 · FY2018 · NS · contact PI
Project 1 Extracellular Vesicles (EVs) Role in GBM Pathobiology$284,671
P01 · FY2018 · CA · contact PI
Core C Interdepartmental Neuroscience Center$208,005
P30 · FY2018 · NS · contact PI
Core A Interdepartmental Neuroscience Center$175,478
P30 · FY2018 · NS · contact PI
Core B Interdepartmental Neuroscience Center$175,230
P30 · FY2018 · NS · contact PI
Core A Administration$148,366
P01 · FY2018 · CA · contact PI
Administration$103,225
P01 · FY2018 · NS · contact PI
Admin Core Interdepartmental Neuroscience Center$67,687
P30 · FY2018 · NS · contact PI
exRNA released by glioblastoma alters brain microenvironment$1,636,002
U19 · FY2017 · CA · contact PI
Extracellular Vesicles (EVs) and Genes in the Biology and Therapy of Gliomas$1,387,951
P01 · FY2017 · CA · contact PI
Molecular etiology of early onset dystonia$1,277,190
P01 · FY2017 · NS · contact PI
Interdepartmental Neuroscience Center$696,000
P30 · FY2017 · NS · contact PI
Mouse models of glioma to study functional exRNA transfer to the microenvironmen$419,247
U19 · FY2017 · CA · contact PI
Intravital Microscopy Core$415,173
U19 · FY2017 · CA · contact PI
Transfer of microRNA regulators from glioblastoma to brain microenvironment$405,296
U19 · FY2017 · CA · contact PI
Mechanisms of exRNA Trafficking$396,286
U19 · FY2017 · CA · contact PI
TorsinA as a key link in receptor-mediated signaling$296,927
P01 · FY2017 · NS · contact PI
Project 1 Extracellular Vesicles (EVs) Role in GBM Pathobiology$284,672
P01 · FY2017 · CA · contact PI
Core C Interdepartmental Neuroscience Center$237,463
P30 · FY2017 · NS · contact PI
Core A Interdepartmental Neuroscience Center$197,308
P30 · FY2017 · NS · contact PI
Core B Interdepartmental Neuroscience Center$197,001
P30 · FY2017 · NS · contact PI
Core A Administration$166,117
P01 · FY2017 · CA · contact PI
Administration$103,224
P01 · FY2017 · NS · contact PI
Admin Core Interdepartmental Neuroscience Center$64,228
P30 · FY2017 · NS · contact PI
exRNA released by glioblastoma alters brain microenvironment$25,000
U19 · FY2017 · CA · contact PI
exRNA released by glioblastoma alters brain microenvironment$1,581,106
U19 · FY2016 · CA · contact PI
Experimental Therapeutics and BioMonitoring for Brain Tumors$1,348,678
P01 · FY2016 · CA · contact PI
Molecular etiology of early onset dystonia$1,277,333
P01 · FY2016 · NS · contact PI
Interdepartmental Neuroscience Center$696,000
P30 · FY2016 · NS · contact PI
Mouse models of glioma to study functional exRNA transfer to the microenvironmen$403,400
U19 · FY2016 · CA · contact PI
Intravital Microscopy Core$399,454
U19 · FY2016 · CA · contact PI
Transfer of microRNA regulators from glioblastoma to brain microenvironment$392,317
U19 · FY2016 · CA · contact PI
Mechanisms of exRNA Trafficking$385,935
U19 · FY2016 · CA · contact PI
exRNA released by glioblastoma alters brain microenvironment$338,000
U19 · FY2016 · CA · contact PI
TorsinA as a key link in receptor-mediated signaling$297,070
P01 · FY2016 · NS · contact PI
Core C Interdepartmental Neuroscience Center$225,404
P30 · FY2016 · NS · contact PI
Microvesicles as potential genetic biomarkers of brain tumors$207,781
P01 · FY2016 · CA · contact PI
Core A Interdepartmental Neuroscience Center$192,880
P30 · FY2016 · NS · contact PI
Core B Interdepartmental Neuroscience Center$192,632
P30 · FY2016 · NS · contact PI
Administration$103,224
P01 · FY2016 · NS · contact PI
Admin Core Interdepartmental Neuroscience Center$85,084
P30 · FY2016 · NS · contact PI
exRNA released by glioblastoma alters brain microenvironment$1,592,843
U19 · FY2015 · CA · contact PI
Experimental Therapeutics and BioMonitoring for Brain Tumors$1,332,561
P01 · FY2015 · CA · contact PI
Molecular etiology of early onset dystonia$1,286,428
P01 · FY2015 · NS · contact PI
Interdepartmental Neuroscience Center$690,198
P30 · FY2015 · NS · contact PI
Mouse models of glioma to study functional exRNA transfer to the microenvironmen$404,578
U19 · FY2015 · CA · contact PI
Intravital Microscopy Core$400,632
U19 · FY2015 · CA · contact PI
Transfer of microRNA regulators from glioblastoma to brain microenvironment$395,879
U19 · FY2015 · CA · contact PI
Mechanisms of exRNA Trafficking$391,754
U19 · FY2015 · CA · contact PI
TorsinA as a key link in receptor-mediated signaling$297,213
P01 · FY2015 · NS · contact PI
Core C Interdepartmental Neuroscience Center$217,474
P30 · FY2015 · NS · contact PI
Microvesicles as potential genetic biomarkers of brain tumors$208,541
P01 · FY2015 · CA · contact PI
Core A Interdepartmental Neuroscience Center$202,817
P30 · FY2015 · NS · contact PI
Core B Interdepartmental Neuroscience Center$194,701
P30 · FY2015 · NS · contact PI
Administration$103,224
P01 · FY2015 · NS · contact PI
Admin Core Interdepartmental Neuroscience Center$75,206
P30 · FY2015 · NS · contact PI
exRNA released by glioblastoma alters brain microenvironment$1,604,204
U19 · FY2014 · CA · contact PI
Experimental Therapeutics and BioMonitoring for Brain Tumors$1,297,716
P01 · FY2014 · CA · contact PI
Interdepartmental Neuroscience Center$801,801
P30 · FY2014 · NS · contact PI
Mouse models of glioma to study functional exRNA transfer to the microenvironmen$405,707
U19 · FY2014 · CA · contact PI
Intravital Microscopy Core$401,761
U19 · FY2014 · CA · contact PI
Transfer of microRNA regulators from glioblastoma to brain microenvironment$399,348
U19 · FY2014 · CA · contact PI
Mechanisms of exRNA Trafficking$397,388
U19 · FY2014 · CA · contact PI
Microvesicles as potential genetic biomarkers of brain tumors$201,599
P01 · FY2014 · CA · contact PI
exRNA released by glioblastoma alters brain microenvironment$100,000
U19 · FY2014 · CA · contact PI
exRNA released by glioblastoma alters brain microenvironment$87,000
U19 · FY2014 · CA · contact PI
exRNA released by glioblastoma alters brain microenvironment$1,662,087
U19 · FY2013 · CA · contact PI
Molecular etiology of early onset torsion dystonia$1,531,348
P50 · FY2013 · NS · contact PI
Experimental Therapeutics and BioMonitoring for Brain Tumors$1,253,475
P01 · FY2013 · CA · contact PI
Interdepartmental Neuroscience Center$796,808
P30 · FY2013 · NS · contact PI
Mouse models of glioma to study functional exRNA transfer to the microenvironmen$418,480
U19 · FY2013 · CA · contact PI
Transfer of microRNA regulators from glioblastoma to brain microenvironment$414,537
U19 · FY2013 · CA · contact PI
Mechanisms of exRNA Trafficking$414,536
U19 · FY2013 · CA · contact PI
Intravital Microscopy Core$414,534
U19 · FY2013 · CA · contact PI
Cellular functions of torsinA$332,711
P50 · FY2013 · NS · contact PI
Microvesicles as potential genetic biomarkers of brain tumors$200,700
P01 · FY2013 · CA · contact PI
Administrative Core$99,809
P50 · FY2013 · NS · contact PI
American Society of Gene & Cell Therapy (ASGCT) 16th Annual Meeting$10,000
R13 · FY2013 · NS · contact PI
Molecular etiology of early onset torsion dystonia$1,586,889
P50 · FY2012 · NS · contact PI
Molecular Genetics of Inherited Neurological Diseases$1,316,946
P01 · FY2012 · NS · contact PI
Interdepartmental Neuroscience Center$817,302
P30 · FY2012 · NS · contact PI
Cellular functions of torsinA$344,777
P50 · FY2012 · NS · contact PI
Vector Query and Therapy For TSC and NF2 Lesions$313,215
P01 · FY2012 · NS · contact PI
Microvesicles as potential genetic biomarkers of brain tumors$222,971
P01 · FY2012 · CA · contact PI
Serum exosome biomarkers for evaluation of glioma drug response$192,488
R21 · FY2012 · CA · contact PI
Administrative Core$103,430
P50 · FY2012 · NS · contact PI
Administration Core$91,971
P01 · FY2012 · NS · contact PI
Molecular etiology of early onset torsion dystonia$1,586,890
P50 · FY2011 · NS · contact PI
Molecular Genetics of Inherited Neurological Diseases$1,316,946
P01 · FY2011 · NS · contact PI
Cellular functions of torsinA$354,534
P50 · FY2011 · NS · contact PI
Vector Query and Therapy For TSC and NF2 Lesions$309,541
P01 · FY2011 · NS · contact PI
Tumor exosomes as agents of genetic change$285,005
R01 · FY2011 · CA · contact PI
Serum exosome biomarkers for evaluation of glioma drug response$230,985
R21 · FY2011 · CA · contact PI
Administrative Core$106,360
P50 · FY2011 · NS · contact PI
Administration Core$90,795
P01 · FY2011 · NS · contact PI
Molecular etiology of early onset torsion dystonia$1,586,890
P50 · FY2010 · NS · contact PI
Molecular Genetics of Inherited Neurological Diseases$1,311,168
P01 · FY2010 · NS · contact PI
Cellular functions of torsinA$354,534
P50 · FY2010 · NS · contact PI
New Vectors and Delivery Systems for Glioblastoma Therapy$332,601
P01 · FY2010 · CA · contact PI
Vector Query and Therapy For TSC and NF2 Lesions$309,542
P01 · FY2010 · NS · contact PI
Tumor exosomes as agents of genetic change$293,820
R01 · FY2010 · CA · contact PI
Novel Reporters and Delivery Vehicles$250,277
P50 · FY2010 · CA · contact PI
Serum exosome diagnosis for glioma$194,700
R21 · FY2010 · CA · contact PI
Administrative Core$106,360
P50 · FY2010 · NS · contact PI
Administration Core$90,795
P01 · FY2010 · NS · contact PI
Molecular etiology of early onset torsion dystonia$1,625,388
P50 · FY2009 · NS · contact PI
Molecular Genetics of Inherited Neurological Diseases$1,324,410
P01 · FY2009 · NS · contact PI
New Vectors and Delivery Systems for Glioblastoma Therapy$335,897
P01 · FY2009 · CA · contact PI
Vector Query and Therapy For TSC and NF2 Lesions$312,549
P01 · FY2009 · NS · contact PI
Tumor exosomes as agents of genetic change$293,682
R01 · FY2009 · CA · contact PI
Cellular functions of torsinA$292,050
P50 · FY2009 · NS · contact PI
Novel Reporters and Delivery Vehicles$252,731
P50 · FY2009 · CA · contact PI
Serum exosome diagnosis for glioma$229,042
R21 · FY2009 · CA · contact PI
Administration Core$91,672
P01 · FY2009 · NS · contact PI
Administrative Core$87,615
P50 · FY2009 · NS · contact PI
Molecular Etiology of Early Onset Torsion Dystonia$23,654
P50 · FY2009 · NS · contact PI
Molecular Genetics of Inherited Neurological Diseases$9,346
P01 · FY2009 · NS · contact PI
Molecular Genetics of Inherited Neurological Diseases$1,423,947
P01 · FY2008 · NS · contact PI
Molecular Etiology of Early Onset Torsion Dystonia$1,307,287
P50 · FY2008 · NS · contact PI
New Vectors and Delivery Systems for Glioblastoma Therapy$326,150
P01 · FY2008 · CA · contact PI
Vector Query and Therapy For TSC and NF2 Lesions$291,359
P01 · FY2008 · NS · contact PI
Novel Reporters and Delivery Vehicles$150,252
P50 · FY2008 · CA · contact PI
Administration Core$85,436
P01 · FY2008 · NS · contact PI
Molecular Etiology of Early Onset Torsion Dystonia$1,341,338
P01 · FY2007 · NS · contact PI
New Vectors and Delivery Systems for Glioblastoma Therapy$322,786
P01 · FY2007 · CA · contact PI
Core--Vector development and production$201,875
P30 · FY2007 · NS · contact PI
Molecular Etiology of Early Onset Torsion Dystonia$1,378,840
P01 · FY2006 · NS · contact PI
Characterization of Dystonia Gene and Protein$401,220
R01 · FY2006 · NS · contact PI
New Vectors and Delivery Systems for Glioblastoma Therapy$230,612
P01 · FY2006 · CA · contact PI
Core--Vector development and production$188,055
P30 · FY2006 · NS · contact PI
Visualizing synaptic circuitry in the retina$169,009
R21 · FY2006 · EY · contact PI
Molecular Genetics of Inherited Neurological Diseases$1,603,281
P01 · FY2005 · NS
Molecular Etiology of Early Onset Torsion Dystonia$1,410,862
P01 · FY2005 · NS
Characterization of Dystonia Gene and Protein$410,875
R01 · FY2005 · NS
Targeted Gene Therapy for Neurologic disease$192,102
R21 · FY2005 · NS
Core--Vector development and production$177,442
P30 · FY2005 · NS
Visualizing synaptic circuitry in the retina$173,076
R21 · FY2005 · EY
Molecular Etiology of Early Onset Torsion Dystonia$15,000
P01 · FY2005 · NS
Molecular Genetics of Inherited Neurological Diseases$1,599,418
P01 · FY2004 · NS
Molecular Etiology of Early Onset Torsion Dystonia$1,421,795
P01 · FY2004 · NS
Characterization of Dystonia Gene and Protein$410,875
R01 · FY2004 · NS
Targeted Gene Therapy for Neurologic disease$177,041
R21 · FY2004 · NS
Visualizing synaptic circuitry in the retina$171,778
R21 · FY2004 · EY
Core--Vector development and production$168,491
P30 · FY2004 · NS
Administrative Core$93,860
P01 · FY2004 · NS
Molecular Genetics of Inherited Neurological Diseases$1,595,669
P01 · FY2003 · NS
Characterization of Dystonia Gene and Protein$410,875
R01 · FY2003 · NS
Core--Vector development and production$163,661
P30 · FY2003 · NS
Molecular Genetics of Inherited Neurological Diseases$1,592,029
P01 · FY2002 · NS
MOLECULAR ETIOLOGY OF EARLY ONSET TORSION DYSTONIA$983,733
P01 · FY2002 · NS
Characterization of Dystonia Gene and Protein$410,875
R01 · FY2002 · NS
Novel vectors$241,412
P50 · FY2002 · CA
Novel vectors$241,412
P50 · FY2002 · CA
NEW VECTORS SYSTEMS FOR EXTENDED GENE DELIVERY$0
P01 · FY2002 · CA
GENE THERAPY FOR HEREDITARY TUMORS IN MODELS OF NF2 % TSC$0
P01 · FY2002 · NS
GENETIC BASIS OF PARKINSON'S DISEASE$0
P50 · FY2002 · NS
Molecular Genetics of Inherited Neurological Diseases$1,615,451
P01 · FY2001 · NS
MOLECULAR ETIOLOGY OF EARLY ONSET TORSION DYSTONIA$981,571
P01 · FY2001 · NS
IDENTIFICATION OF THE DYSTONIA GENE$256,784
R01 · FY2001 · NS
Novel vectors$241,412
P50 · FY2001 · CA
IDENTIFICATION OF THE DYSTONIA GENE$50,000
R01 · FY2001 · NS
IDENTIFICATION OF THE DYSTONIA GENE$30,000
R01 · FY2001 · NS
GENETIC BASIS OF PARKINSON'S DISEASE$0
P50 · FY2001 · NS
GENETIC BASIS OF PARKINSON'S DISEASE$0
P50 · FY2001 · NS
Novel vectors$0
P50 · FY2001 · CA
GENE THERAPY FOR HEREDITARY TUMORS IN MODELS OF NF2 % TSC$0
P01 · FY2001 · NS
NEW VECTORS SYSTEMS FOR EXTENDED GENE DELIVERY$0
P01 · FY2001 · CA
MOLECULAR ETIOLOGY OF EARLY ONSET TORSION DYSTONIA$987,887
P01 · FY2000 · NS
IDENTIFICATION OF THE DYSTONIA GENE$246,908
R01 · FY2000 · NS
HSV/AAV HYBRID VECTORS FOR GENE REPLACEMENT$170,274
R21 · FY2000 · MH
GENETIC BASIS OF PARKINSON'S DISEASE$121,168
P50 · FY2000 · NS
Novel vectors$0
P50 · FY2000 · CA