← LeaderboardsInvestigatorsiAttributed = a PI's even-split share of each grant — a $1M grant with 2 PIs counts $500K each.
Center For Aquaculture Technologies, Inc.
$849,834
Total funding
3
Grants
Funding over time
peak $500K · FY2018–22$500K$375K$250K$125K$0
'18
'19
'20
'21
'22
Funding mix
By agency
USDA$849,834 · 3
By mechanism
—$849,834 · 3
Investigators at Center For Aquaculture Technologies, Inc.
InvestigatorsiAttributed = a PI's even-split share of each grant — a $1M grant with 2 PIs counts $500K each.
Exposure= the full size of every grant they're on ($1M each).
Rising Stars
First grant in the last 5 yrs
Not enough data
Emerging Leaders
6–10 yrs in
Not enough data
All-Time
Most funded here, all years
Not enough data
Largest grants
**AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** PARTIAL INACTIVATION OF MATERNAL GENE (PIMG) TECHNOLOGY FOR THE GENETIC CONTAINMENT OF GE FISH$499,996
· FY2022 · National Institute of Food and Agriculture
MULTIPLE SPECIES OF FISH HAVE BEEN GENETICALLY ENGINEERED (GE) TO INCORPORATE ADVANTAGEOUS TRAITS FOR AQUACULTURE OR TO PRODUCE VALUABLE PHARMACEUTICAL PROTEINS. UNFORTUNATELY, WIDESPREAD ADOPTION OF THESE GE FISH IS HAMPERED BY CONCERNS OVER THEIR ACCIDENTAL RELEASE TO NATURAL ECOSYSTEMS. FAILPROOF STERILIZATION TECHNIQUES WOULD BE INVALUABLE FOR MINIMIZING THE IMPACT OF GE FISH LINES. STERILE FISH HAVE BEEN PRODUCED BY TRIPLOIDIZATION, TRANSGENIC APPROACHES, AND A VARIETY OF TRANSIENT GENE SILENCING METHODOLOGIES. HOWEVER, THESE APPROACHES OFTEN REMAIN TECHNICALLY DIFFICULT, COSTLY AND INSUFFICIENTLY ROBUST OR SCALABLE TO BE USED IN COMMERCIAL SETTINGS. TO DISCOVER NOVEL AND EFFECTIVE MEANS OF STERILIZING FISH, WE PROPOSE TO INVESTIGATE INDUCED MUTATIONS ACROSS A COMBINATION OF GENES NECESSARY FOR SPERMIOGENESIS AND STEROID HORMONE SYNTHESIS; RESULTING IN MALE STERILITY AND MASCULINIZATION RESPECTIVELY. MORE SPECIFICALLY, DOUBLE MUTANT COMBINATIONS OF GENES SHOULD PRODUCE ALL-MALE STERILE POPULATIONS. LIKEWISE, DOUBLE MUTANT COMBINATIONS OF GENES RESPONSIBLE FOR MALENESS AND FOLLICULOGENESIS SHOULD RESULT IN STERILE ALL-FEMALE POPULATIONS. THUS, OUR PROPOSED PROJECT WILL GENERATE AND CHARACTERIZE 14 DIFFERENT LINES OF TILAPIA CARRYING NULL MUTATIONS IN TWO GENETIC PATHWAYS SIMULTANEOUSLY, ONE GOVERNING SEX DIFFERENTIATION AND THE OTHER SEX/GAMETE COMPETENCY. WE WILL ALSO DEVELOP STRATEGIES TO GENERATE BROODSTOCK CAPABLE OF PROPAGATING THESE MUTANT LINES, THROUGH USE OF SEX-REVERSAL AND TRANSPLANTATION APPROACHES AIMED RESPECTIVELY AT RESCUING THE MISSING GENDER AND RESTORING GAMETE PRODUCTION. FINALLY, WE WILL TEST THE PERFORMANCE OF THESE LINES IN GROW-OUT TRIALS. IF SUCCESSFUL, THIS PROJECT WILL ENABLE SAFE AND EFFECTIVE UTILIZATION OF GE FISH IN A WIDE RANGE OF COMMERCIAL APPLICATIONS. THUS, OUR PROJECT ALIGNS WELL WITH USDA BRAG PROGRAM AREA #1: MANAGEMENT PRACTICES TO MINIMIZE ENVIRONMENTAL RISK OF GE ORGANISMS.$249,838
· FY2018 · National Institute of Food and Agriculture
MATERNAL SPECIFIC MUTATIONS CAUSING LOSS OF PRIMODIAL GERM CELL TO PRODUCE STERILE FISH POPULATIONS WITH IMPROVED CULTURE PERFORMANCE.$100,000
· FY2019 · National Institute of Food and Agriculture