FUNCTIONAL ANALYSIS OF ASTROCYTE DERIVED APOE3 AND APOE4

$0M01FY2000RRNIH

Washington University, Saint Louis MO

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Abstract

In this study, we are trying to determine whether a subject's apoE genotype influences CNS lipid and cholesterol metabolism as well as its influence on the amyloid beta protein. The amyloid beta protein is felt to play an important role in Alzheimer's disease pathogenesis.

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