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17,054 grants matching genome editing

High-throughput investigation of human genetic variants affecting cholesterol uptake and efflux

$783,155
Richard I Sherwood · Brigham And Women'S Hospital · R01 · FY2025 · HL

A Mouse Model Resource for Peroxisome Research

$782,684
Joseph G Hacia · University Of Southern California · R24 · FY2022 · OD

Integration of the results from systems-level determination of cis-acting elements into high-resolution maps of posttranscriptional regulatory events.

$782,584
Markus Hafner · National Institute Of Arthritis And Musculoskeletal And Skin Diseases · ZIA · FY2024 · AR

Focused Ultrasound-mediated Delivery of Gene-editing Elements to the Brain for Neurodegenerative Disorders

$782,568
Kam W Leong · Columbia University Health Sciences · UG3 · FY2020 · NS

Efficient in Vivo RNP-based Gene Editing in the Sensory Organ Inner Ear Using Bioreducible Lipid Nanoparticles

$782,510
Zheng-Yi Chen · Massachusetts Eye And Ear Infirmary · UG3 · FY2020 · TR

Modeling the complex genetics of congenital heart disease in mice

$782,429
Cecilia W. Lo · University Of Pittsburgh At Pittsburgh · R01 · FY2016 · HL

Enhancing The Value of Pigs for Agriculture and Biomedical Applications By Using Novel Genome Editing Strategies

$781,761
Kiho Lee · University Of Missouri-Columbia · R01 · FY2023 · OD

Combined Molecular Excision Therapy (CMET) for Eliminating HIV-1

$781,703
Howard Eliot Gendelman · University Of Nebraska Medical Center · R01 · FY2017 · MH

Uncovering the genetically-driven differential susceptibility to chronic obstructive pulmonary disease and pulmonary fibrosis

$781,643
Michael H. Cho · Brigham And Women'S Hospital · R01 · FY2023 · HL

Development of Swine Reporter Models for Testing Somatic Cell Genome Editing Tools

$781,473
Daniel Fred Carlson · Recombinetics, Inc. · U24 · FY2021 · OD

Novel SETD5-based Molecular Mechanisms and Therapeutic Tools to Understand and Revert Neuronal Dysfunction Associated with Intellectual disability and Autism

$781,258
Alysson R. Muotri · University Of California, San Diego · R01 · FY2025 · MH

Cas9 RNP delivery to immune cells in vivo via molecular targeting

$781,190
Ross C Wilson · University Of California Berkeley · UG3 · FY2020 · AI

tRNA modifications regulating mitochondrial function and the mitochondrial proteome in AD/ADRD

$781,008
Xiaoling Zhang · Boston University Medical Campus · R01 · FY2025 · AG

Development and Clinical Application of Gene and Cell therapies for Patients with Immune Deficiencies

$780,813
Suk See De Ravin · National Institute Of Allergy And Infectious Diseases · ZIA · FY2023 · AI

Multiplex Epitope Editing to Enable Novel Immunotherapies for Acute Myeloid Leukemia

$780,389
Pietro Genovese · Boston Children'S Hospital · R01 · FY2024 · CA

Impact of coding and non-coding variation in progressive supranuclear palsy

$780,382
Daniel H Geschwind · University Of California Los Angeles · UH3 · FY2021 · NS

Elucidating endolysosomal trafficking dysregulation induced by APOE4 in human astrocytes

$780,310
Julia Tcw · Boston University Medical Campus · R01 · FY2025 · AG

Genetic and therapeutic studies of hemostatic and thrombotic disorders using zebrafish

$780,000
Jordan A Shavit · University Of Michigan At Ann Arbor · R35 · FY2023 · HL

Genetic and therapeutic studies of hemostatic and thrombotic disorders using zebrafish

$780,000
Jordan A Shavit · University Of Michigan At Ann Arbor · R35 · FY2021 · HL

Genetic and therapeutic studies of hemostatic and thrombotic disorders using zebrafish

$780,000
Jordan A Shavit · University Of Michigan At Ann Arbor · R35 · FY2022 · HL

Genetic and therapeutic studies of hemostatic and thrombotic disorders using zebrafish

$780,000
Jordan A Shavit · University Of Michigan At Ann Arbor · R35 · FY2025 · HL

University of Michigan Skin Biology and Diseases Resource-based Center

$780,000
Johann Eli Gudjonsson · University Of Michigan At Ann Arbor · P30 · FY2019 · AR

Genetic and therapeutic studies of hemostatic and thrombotic disorders using zebrafish

$780,000
Jordan A Shavit · University Of Michigan At Ann Arbor · R35 · FY2020 · HL

Discovering Chemical Activity Networks-Predicting Bioactivity Based on Structure

$779,811
Robert L Tanguay · Oregon State University · R35 · FY2021 · ES

Determinants of oral anaphylaxis to food

$779,775
Adam Williams · Northwestern University At Chicago · R01 · FY2025 · AI