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78,016 grants matching “breast cancer”
MUSCULOSKELETAL COMPLICATIONS AND BONE METASTASES IN BREAST CANCER PATIENTS UNDERGOING ESTROGEN DEPRIVATION THERAPY
$436,510Trustees Of Indiana University · · FY2014 · Department of the Army
Obesity Related Methylation Markers for Obesity-related Cancers
$436,506Naisi Zhao · University Of Kansas Medical Center · R21 · FY2025 · CA
The Mechanism and Therapeutic Potential of Targeting the Ninjurin Pathway for Tumors Carrying Wild-Type p53
$436,503Xinbin Chen · University Of California At Davis · R01 · FY2025 · CA
Examination of Ornithine Decarboxylase Antizyme RNA Structure and Function for the Development of Antibiological Agents
$436,500Juliane K Strauss-Soukup · Creighton University · R15 · FY2018 · GM
A novel biotherapeutic for triple-negative breast cancer.
$436,500Randolph C Elble · Southern Illinois University Sch Of Med · R15 · FY2010 · CA
Deciphering the tumor suppressive functions of macroH2A
$436,463Emily Bernstein · Icahn School Of Medicine At Mount Sinai · R01 · FY2018 · CA
A unique approach combining avatar mice and targeted mass spectrometry to identify blood biomarkers for early detection of breast cancer
$436,457Amanda G Paulovich · Fred Hutchinson Cancer Research Center · U01 · FY2020 · CA
Diagnosis and Treatment of APOBEC Mutagenesis in Metastatic Breast Cancer
$436,454Sarat Chandarlapaty · Sloan-Kettering Inst Can Research · P50 · FY2021 · CA
Diagnosis and Treatment of APOBEC Mutagenesis in Metastatic Breast Cancer
$436,454Sarat Chandarlapaty · Sloan-Kettering Inst Can Research · P50 · FY2023 · CA
Engineered ECM platforms to analyze progression in high grade serous ovarian cancer
$436,446Pamela K Kreeger · University Of Wisconsin-Madison · R01 · FY2019 · CA
Multiplexed time domain fluorescence tomography of tumor biomarkers during immunotherapy
$436,422Anand T.n. Kumar · Massachusetts Eye And Ear Infirmary · R01 · FY2024 · CA
Engineered ECM platforms to analyze progression in high grade serous ovarian cancer
$436,391Pamela K Kreeger · University Of Wisconsin-Madison · R01 · FY2018 · CA
NG2-PG in tumor vascularization and progression
$436,389William B Stallcup · Sanford Burnham Prebys Medical Discovery Institute · R01 · FY2015 · CA
Novel regulations of DNA damage repair
$436,368Junjie Chen · University Of Tx Md Anderson Can Ctr · R01 · FY2020 · CA
Novel regulations of DNA damage repair
$436,368Junjie Chen · University Of Tx Md Anderson Can Ctr · R01 · FY2021 · CA
CORE--GENOMICS AND BIOINFORMATICS
$436,336Charles M Perou · Univ Of North Carolina Chapel Hill · P30 · FY2008 · CA
MR Guided Focused Ultrasound Surgery for Prostate Cancer
$436,323Clare M Tempany · Brigham And Women'S Hospital · R01 · FY2009 · CA
Redox Mechanism Process of Angiogenesis and Wound Healing
$436,316David Wink · Division Of Basic Sciences - Nci · Z01 · FY2008 · CA
BRCA1, DNA damage response and aging
$436,301Chuxia Deng · National Institute Of Diabetes And Digestive And Kidney Diseases · ZIA · FY2009 · DK
Chemoprevention and therapeutic treatment of BRCA1 associated mammary tumors
$436,301Chuxia Deng · National Institute Of Diabetes And Digestive And Kidney Diseases · ZIA · FY2009 · DK
Role of Erbb3 kinase activity in colorectal tumorigenesis.
$436,262Zhenghe Wang · Case Western Reserve University · R01 · FY2025 · CA
Monitoring neoadjuvant chemotherapy of breast cancer using 3D subharmonic aided pressure estimation
$436,253Kibo Nam · Thomas Jefferson University · R37 · FY2020 · CA
Choice Points: Breast Cancer Treatment CD-ROM
$436,249Healthmark Multimedia, Llc · R44 · FY2001 · CA
**AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** SOY IS PERVASIVE IN OUR LIFE. IT SERVES AS A KEY SOURCE OF VEGETABLE PROTEIN AND OIL, AND SOYBEANS CAN BE MADE INTO FOOD PRODUCTS LIKE TOFU, SOY SAUCE, AND MEAT SUBSTITUTES. ANOTHER REASON FOR SOY FOOD AS A VERY POPULAR PRODUCT IN THE GLOBAL FOOD MARKET IS ITS BENEFICIAL EFFECTS ON HUMAN HEALTH, FOR EXAMPLE, REDUCING RISKS OF CARDIOVASCULAR DISEASES THROUGH CONTROL OF CHOLESTEROL LEVELS, ATTENUATING DIABETES SYMPTOMS THROUGH REGULATION OF GLUCOSE METABOLISM, AND PREVENTING AND REDUCING RELAPSE OF BREAST CANCER. AS THE ASIAN PACIFIC POPULATION ACCOUNTS FOR THE LARGEST CONSUMER OF SOY FOOD WORLDWIDE, ASIAN WOMEN BENEFIT FROM THEIR EATING HABITS WITH A LOWER RATE OF BREAST CANCER THAN THEIR WESTERN COUNTERPARTS. NEVERTHELESS, IT HAS BEEN REPORTED THAT AMERICANS CONSUME VERY FEW SOY FOOD OR ITS-DERIVED PRODUCTS IN THEIR DIETS PARTIALLY DUE TO THE CONTROVERSIAL DEBATES WITH RESPECT TO THE POTENTIAL PHYTOESTROGENIC EFFECTS OF SOY FOOD.OUR LABORATORY HAS BEEN STUDYING SOYBEAN PRODUCT AND ITSEFFECTS ON HUMAN HEALTH FOR MORE THAN DECADE AND DEVELOPED STRONG EVIDENCE IN SUPPORT OF ITS BENEFICIAL EFFECTS ON OVERALL HUMAN HEALTH, WHICH OUTWEIGHS ITS SUBTLE ESTROGENIC EFFECTS. WE THEREFORE BELIEVE OUR RESEARCH IS IMPORTANT BECAUSE IT CAN NOT ONLY PROVIDE KNOWLEDGE TO GUIDE PUBLIC HEALTH, BUT MAY ALSO HELP TO INCREASE SOY FOOD MARKETS IN THE UNITED STATES IF THE NOTIONS AGAINST THE USE OF SOYBEAN PRODUCTS COULD BE CORRECTED BY OUR STUDY.BREAST CANCER AND OBESITY-RELATED DISEASES AFFECT HUNDREDS OF THOUSANDS OF PEOPLE WORLD-WIDE AND ELUCIDATION OF ITS PREVENTION THROUGH NATURAL BIOACTIVE FOODS LIKE SOY WILL HAVE GLOBAL IMPACT. IN ALIGNMENT WITH NIFA AND USDA RESEARCH PRIORITIES, OUR PROPOSED STUDY SEEKS TO PROVIDE THE SCIENTIFIC FOUNDATION AND ADDRESS PUBLIC DEMANDS FOR SAFE AND PROPER USE OF NUTRITIOUS SOY FOOD, USING A TRANSDISCIPLINARY APPROACH THAT CLOSELY MIMICS HUMAN PATHOLOGICAL PROCESSES, AND TO DEFINE PREVIOUSLYUNDERSTUDIED AREAS FOR APPROPRIATELY APPLYING SOY FOOD DURING MATERNAL LIFE IN IMPROVING HUMAN HEALTH THROUGH GENERATIONS. SCIENTIFICALLY, WE WILL ELUCIDATE THE MECHANISMS HOW MATERNAL SOY DIET MAY INFLUENCE INITIAL GUT MICROBIOME-MODULATED DEVELOPMENTAL ORIGINS OF OBESITY AND BREAST CANCER AS WELL AS INTERACTIONS BETWEEN THESE TWO MALADIES, WHICH WILL FACILITATE EXPLORATION OF A NOVEL PREVENTIVE STRATEGY THROUGH APPROPRIATE CONSUMPTION OF MATERNAL SOY-BASED NATURAL BIOACTIVE PRODUCTS AND/OR AN OPTIMIZED PANEL OF BENEFICIAL BACTERIA FROM CHILDHOOD LEADING TO IMPROVED HUMAN HEALTH LATER IN LIFE. EVENTUALLY, THIS STUDY WILL GREATLY ADVANCE KNOWLEDGE IN BOTH FUNDAMENTAL AND APPLIED SCIENCES IMPORTANT TO SOY AGRICULTURE, WHICH SHOWS TREMENDOUS IMPACT IN BOTH PUBLIC HEALTH AND FOOD MARKET IN A LONG-RANGE PERSPECTIVE OF VIEW.
$436,207University Of Maryland, College Park · · FY2023 · National Institute of Food and Agriculture
Modeling Autism and Comorbid Cancer Risk in Individuals with Germline PTEN Mutations
$436,173Charis Eng · Cleveland Clinic Lerner Com-Cwru · R01 · FY2022 · HD