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17,828 grants matching crispr

Drosophila models of human mitochondrial diseases

$867,258
Norbert Perrimon · Harvard Medical School · R24 · FY2023 · OD

Structure and Mechanism: Hsp90 proteostasis, cilia biogenesis and the jumbo phage “nucleus”

$867,180
David A Agard · University Of California, San Francisco · R35 · FY2021 · GM

CRISPR detection of circulating cell-free Mycobacterium avium complex (MAC) DNA for rapid diagnosis and monitoring of MAC pulmonary disease

$866,858
Kevin Loring Winthrop · Oregon Health & Science University · R01 · FY2024 · AI

Human‐specific vulnerabilities and compensatory adaptations to age‐related stressors in selectively vulnerable midbrain dopaminergic neurons

$866,764
Alexander A Pollen · University Of California, San Francisco · R01 · FY2024 · AG

01 Sequencing and Microarray Facility

$865,492
Vicki Huff · University Of Tx Md Anderson Can Ctr · P30 · FY2025 · CA

Project 1: CRISPR screens to discover regulators of CD8 and CD4 cell fates and function

$865,355
Arlene H Sharpe · Harvard Medical School · U19 · FY2021 · AI

Late stage signaling centers and Gli3-Hoxd interaction roles in Hedgehog regulated digit morphogenesis

$864,985
Susan Mackem · Division Of Basic Sciences - Nci · ZIA · FY2025 · CA

TET enzymes as guardians of genome stability

$864,061
Anjana Rao · La Jolla Institute For Immunology · R35 · FY2016 · CA

B cell determinants of EBV latency

$864,001
Ethel Cesarman · Weill Medical Coll Of Cornell Univ · U01 · FY2022 · CA

Development of the UValidate platform for the profiling of topically applied chemical agents.

$863,724
Peter Sykora · Amelia Technologies, Llc · R42 · FY2023 · ES

COPD Susceptibility, Heterogeneity, and Progression: Proteomics and Genetics

$863,197
Edwin K Silverman · Brigham And Women'S Hospital · R01 · FY2025 · HL

Non-coding RNAs in resilience to Alzheimer’s Disease

$862,503
Frank J. Slack · Beth Israel Deaconess Medical Center · R01 · FY2023 · AG

Enhancing Susceptibility of HIV Reservoirs to CTL Through a Discovery to Translational Approach

$862,207
R. Brad Jones · Weill Medical Coll Of Cornell Univ · R01 · FY2023 · AI

Environmental Epigenomics and Precision Environmental Health

$861,880
Dana Dolinoy · University Of Michigan At Ann Arbor · R35 · FY2024 · ES

Effects of 16p11.2 copy number variation on neuronal development and pathology

$861,572
Mustafa None Sahin · Boston Children'S Hospital · R01 · FY2023 · MH

Minimizing in vivo Drug Tolerance induction in tuberculosis.

$861,173
David G Russell · Rutgers Biomedical And Health Sciences · U19 · FY2025 · AI

Deep mutational scanning of MYH7 in genome-edited cardiomyocytes

$859,932
Kai-Chun Daniel Yang · University Of Washington · R01 · FY2024 · HL

High-throughput genome engineering

$859,755
Meru Sadhu · National Human Genome Research Institute · ZIA · FY2022 · HG

Novel strategies for induction of aging in human PSC-derived lineages for modeling Alzheimer's Disease

$859,466
Lorenz P. Studer · Sloan-Kettering Inst Can Research · R01 · FY2025 · AG

Mechanisms of chromosome segregation, aneuploidy, and tumorigenesis

$858,918
Don W. Cleveland · Ludwig Institute For Cancer Res Ltd · R35 · FY2020 · GM

Mechanisms of chromosome segregation, aneuploidy, and tumorigenesis

$858,918
Don W. Cleveland · Ludwig Institute For Cancer Res Ltd · R35 · FY2021 · GM

Mechanisms of chromosome segregation, aneuploidy, and tumorigenesis

$858,918
Don W. Cleveland · Ludwig Institute For Cancer Res Ltd · R35 · FY2018 · GM

Mechanisms of chromosome segregation, aneuploidy, and tumorigenesis

$858,918
Don W. Cleveland · Ludwig Institute For Cancer Res Ltd · R35 · FY2019 · GM

Higher Order Chromatin and Genetic Risk for Schizophrenia

$858,519
Schahram Akbarian · Icahn School Of Medicine At Mount Sinai · R01 · FY2020 · MH

Role of N-terminal acetylation in alpha synuclein stability, function, and therapeutic targeting in synucleinopathies

$858,471
Elizabeth Rhoades · University Of Pennsylvania · R01 · FY2024 · NS