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64,565 grants matching drug discovery

Target discovery and combination therapy in KRAS mutant cancer

$473,481
Ji Luo · Division Of Basic Sciences - Nci · ZIA · FY2022 · CA

Overcoming resistance to targeted therapy in cancer

$473,472
Levi Alexander Garraway · Dana-Farber Cancer Inst · R35 · FY2015 · CA

Expanding the Chemical Biology of K2P Channels with Selective Cellular and In vivo Probes

$473,430
Adam R Renslo · University Of California, San Francisco · R01 · FY2020 · MH

Biomolecular Recognition and Binding Mechanisms

$473,373
Ruth Nussinov · Division Of Basic Sciences - Nci · ZIA · FY2020 · CA

Bayesian Network-Based Integrative Genomics Methods for Precision Medicine

$473,363
Jeffrey S. Morris · University Of Pennsylvania · R01 · FY2021 · CA

Preclinical Development of First-in-Class NDUFS7 Antagonists for the Treatment of Pancreatic Cancer

$473,270
Nouri Neamati · University Of Michigan At Ann Arbor · R01 · FY2022 · CA

Integrated Instrument System for Single Cell Genomics

$473,255
Leonid S Metelitsa · Baylor College Of Medicine · S10 · FY2015 · OD

Rock Inhibition as Therapy for Cerebral Cavernous Malformation

$473,253
Issam A Awad · University Of Chicago · R01 · FY2014 · NS

Chemistry Core

$473,246
Douglas E Frantz · Ut Southwestern Medical Center · P01 · FY2011 · CA

Metabolic Imaging of the Cardioprotective Effects of Alcohol and ALDH2 Activators

$473,237
Daniel M Spielman · Stanford University · R01 · FY2011 · AA

High-Content Screen to Identify Small Molecule Therapeutics that Reduce Aberrant Lipid Accumulation in APOE4 Alzheimer's Disease

$473,216
Kelvin T Lam · Mcm6 Therapeutics, Inc. · R41 · FY2024 · AG

Regulatory T cells in Autoimmune Disease

$473,150
Charles Garrison Fathman · Yale University · U19 · FY2011 · AI

Resources for Teleost Gene Duplicates and Human Disease

$473,109
John Harvey Postlethwait · University Of Oregon · R01 · FY2016 · OD

Regulation of apoptosis by PI 3-kinase/Akt signaling

$473,090
Geoffrey M Cooper · Boston University (Charles River Campus) · R01 · FY2008 · CA

MECHANISMS OF POL II ELONGATION IN DIFFUSE MIDLINE GLIOMA

$473,032
Jamie N. Anastas · Baylor College Of Medicine · R01 · FY2023 · NS

Terpene Condensation Reactions

$472,991
Charles Dale Poulter · University Of Utah · R56 · FY2009 · GM

Development of cell-free DNA assays for HCC screening and liquid biopsy

$472,981
Ying-Hsiu Su · Baruch S. Blumberg Institute · R01 · FY2017 · CA

Leadership Group for the Infectious Diseases Clinical Research Consortium (IDCRCLG) - Moderna Boost {Supplement #5}

$472,962
David S Stephens · Emory University · UM1 · FY2021 · AI

Signature-Directed Combination Mitigator Therapy Based on GS-Nitroxides

$472,947
Joel S Greenberger · University Of Pittsburgh At Pittsburgh · U19 · FY2017 · AI

HIV Tat and Opiate-mediated aberrations in glial-neuronal crosstalk: Implications for the role of extracellular RNA in HAND

$472,930
Shilpa J Buch · University Of Nebraska Medical Center · R01 · FY2025 · DA

Significance of UBIAD1 in Regulation of HMG CoA Reductase Degradation, Mevalonate Metabolism, and Menaquinone-4 Synthesis

$472,924
Russell Alfred Debose-Boyd · Ut Southwestern Medical Center · R01 · FY2023 · GM

Coordination of stress-adaptive cell states by CRIPTO in breast cancer heterogeneity and progression

$472,921
Benjamin T Spike · Utah State Higher Education System--University Of Utah · R01 · FY2025 · CA

E3 ubiquitin ligase RNF145 in airway smooth muscle functions and in asthma

$472,898
Pawan Sharma · Thomas Jefferson University · R01 · FY2023 · HL

E3 ubiquitin ligase RNF145 in airway smooth muscle functions and in asthma

$472,898
Pawan Sharma · Thomas Jefferson University · R01 · FY2022 · HL

Inflammation in Vascular Injury and Repair

$472,847
Daniel I Simon · Case Western Reserve University · R37 · FY2012 · HL