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21,281 grants matching “influenza”
ELC FOR INFECTIOUS DISEASES INFLUENZA ENHANCEMENTS
$70,330Marion Angelika Kainer · Tennessee State Department Of Health · U50 · FY2007 · CI
Mechanism of pulmonary vascular wall thickening in COVID-19
$70,304Yuichiro Justin Suzuki · Georgetown University · R03 · FY2022 · AG
Viral Pathogenesis Training Program
$70,208Julie M Overbaugh · University Of Washington · T32 · FY2009 · AI
INFLUENZA IMMUNITY: PROTECTIVE MECHANISMS AGAINST A PANDEMIC RESPIRATORY VIRUS
$70,164Stanford University · M01 · FY2005 · RR
Epigenetic Regulation of the Maturation and Function of Lung Epithelium by the SWI/SNF Proteins ARID1A and ARID1B.
$70,095William John Zacharias · Cincinnati Childrens Hosp Med Ctr · R01 · FY2024 · HL
Task B10: In Vitro Assessments for Respiratory Viruses
$70,070Norman Kneteman · Utah State University · N01 · FY2013 · AI
Vaccine development for Group B Neisseria meningitidis and Escherichia coli K1
$70,024Rachel Schneerson · Eunice Kennedy Shriver National Institute Of Child Health & Human Development · ZIA · FY2011 · HD
Combinational Regulation of Inflammation in Otitis Media
$70,000Jian-Dong Li · Georgia State University · R01 · FY2014 · DC
GH13-003: Hospital - Based Surveillance of Acute Febrile Illness in Western Ghat Region of
$70,000Arunkumar Govindakarnavar · Manipal Academy Of Higher Education · U01 · FY2015 · GH
Belmont Forum Collaborative Research: Health and agriculture sustainability through interdisciplinary surveillance and risk assessment platform of global emerging zoonotic diseases
$70,000Beatriz Martinez Lopez · University Of California-Davis · · FY2021 · GEO
GH21-001, Conducting Public Health Research in Thailand: Technical collaboration with the Ministry of Public Health (MOPH) in the Kingdom of Thailand
$70,000Opart Karnkawinpong · Thailand Ministry Of Public Health · U01 · FY2025 · GH
Disease severity of otitis media: Biofilms, invasion, and host responses
$70,000Kevin M Mason · Research Inst Nationwide Children'S Hosp · R01 · FY2014 · DC
Pilot Project
$69,965Anna Karolina Palucka · Baylor Research Institute · U19 · FY2011 · AI
Deciphering the Double-Edged Role of IFITM3 during SARS-CoV-2 Infection
$69,947Alex Compton · Division Of Basic Sciences - Nci · ZIA · FY2022 · CA
SPLUNC1 and Neutrophilic Inflammation in Cystic Fibrosis
$69,930Clemente Britto-Leon · Yale University · K01 · FY2021 · HL
Effect of Community Wide Deworming on Hookworm Modulated Immune Responses to Bystander Antigens and Vaccines in Southern India
$69,906Sitara Swarna Rao Ajjampur · Christian Medical College · K43 · FY2023 · TW
Investigating the cellular responses to influenza virus infection and the origins of first exposure immune imprinting
$69,802Robert C Mettelman · St. Jude Children'S Research Hospital · F32 · FY2022 · AI
Controlling Vaccine Kinetics with Small Molecule Drugs
$69,802Parisa Yousefpour · Massachusetts Institute Of Technology · F32 · FY2022 · AI
Therapeutically harnessing anti-viral resident memory T cells in solid tumors
$69,771Pamela Rosato · Dartmouth College · R01 · FY2024 · CA
Infectious Disease Screening Platforms
$69,740Emily Lee · National Center For Advancing Translational Sciences · ZIA · FY2025 · TR
Epidemiology and Transmission of Influenza in Nicaragua
$69,690Aubree L Gordon · University Of Michigan At Ann Arbor · K02 · FY2014 · TW
Epidemiology and Transmission of Influenza in Nicaragua
$69,690Aubree L Gordon · University Of California Berkeley · K02 · FY2014 · TW
In Vivo Virulence Gene Expression in Acute Otitis Media
$69,669Ha-Sheng Li-Korotky · Children'S Hosp Pittsburgh/Upmc Hlth Sys · R03 · FY2008 · DC
In Vivo Virulence Gene Expression in Acute Otitis Media
$69,669Ha-Sheng Li-Korotky · Children'S Hosp Pittsburgh/Upmc Hlth Sys · R03 · FY2007 · DC
INFLUENZA OR FLU IS ONE OF TOP 3 ECONOMIC DISEASES AFFECTING THE PORK INDUSTRY. IN HUMANS, IT CAUSES UP TO 41,000 HUMAN FATALITIES IN UNITED STATES AND UPWARDS OF 500,000 CASUALTIES WORLDWIDE. PIGS SERVE AS RESERVOIRS FOR SWINE, AVIAN, AND HUMAN VIRUSES AND PRODUCE NOVEL HIGH POTENCY STRAINS, SIMILAR TO THE "SWINE FLU" PANDEMIC H1N1 STRAIN. OUR HYPOTHESIS IS THAT ELIMINATING RECEPTORS FOR VIRAL ENTRY AND INTERFERING WITH VIRAL REPLICATION WILL SERVES AS A DUAL MECHANISM FOR PROTECTING THE PIGS FROM VIRAL INFECTION, AND TRANSMISSION OF FLU TO HUMAN AND PIG HOSTS. THERE ARE THREE OBJECTIVES IN THE PROPOSAL: 1) ASSEMBLE AND VALIDATE GENOME EDITING TOOLS TO DELETE THE RECEPTOR FOR FLU VIRUS ENTRY, AND PREVENT VIRAL PROPAGATION; 2) GENERATE RECOMBINANT PIGS; AND 3) TEST THE RECOMBINANT PIGS FOR SUSCEPTIBILITY TO INFECTION BY SWINE AND HUMAN TYPE ADAPTED VIRUSES TO INFECTION AND DISSEMINATION. WE EXPECT TO DEVELOP A PIG MODEL OF INFLUENZA RESEARCH AND IDENTIFY DRUGGABLE TARGETS. FROM AGRICULTURAL STAND POINT, WE ANTICIPATE ELIMINATION OF FLU FROM COMMERCIAL SWINE HERDS.
$69,646University Of Maryland, College Park · · FY2015 · National Institute of Food and Agriculture