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10,766 grants matching checkpoint inhibitor

Structure and function of RAD51 paralog tumor suppressor complexes in genome maintenance

$640,408
Shaun Olsen · University Of Texas Hlth Science Center · R01 · FY2025 · CA

Ascorbic acid as a pharmacologic agent in disease treatment

$640,390
Mark A Levine · National Institute Of Diabetes And Digestive And Kidney Diseases · ZIA · FY2024 · DK

Uncovering the metabolic underpinnings of T cell exhaustion

$640,384
Greg M. Delgoffe · University Of Pittsburgh At Pittsburgh · R01 · FY2024 · AI

Uncovering the metabolic underpinnings of T cell exhaustion

$640,384
Greg M. Delgoffe · University Of Pittsburgh At Pittsburgh · R01 · FY2023 · AI

The Genetics of Ocular Melanoma

$640,346
Anne Mary Bowcock · Icahn School Of Medicine At Mount Sinai · R01 · FY2023 · CA

Serial immunotherapy combination to modulate the tumor environment in patients with metastatic gastroesophageal cancer

$640,182
Harry H Yoon · Mayo Clinic Rochester · R01 · FY2021 · CA

Constrained Fetal Hematopoiesis and Clonal Restriction in Fanconi Anemia

$640,103
Peter Kurre · Children'S Hosp Of Philadelphia · R01 · FY2023 · HL

Cachexia-mediated FcRn Modulation and Its Impact on Anti-PD1 Therapy in Lung Cancer

$639,862
Mitch A Phelps · Ohio State University · R01 · FY2022 · CA

Synthetic lethalities to cell cycle disruption in glioma

$639,818
Rameen Beroukhim · Dana-Farber Cancer Inst · R01 · FY2024 · CA

Personalized vaccine immunotherapy in combination with anti-PD 1 antibody for recurrent or metastatic squamous cell carcinoma of the head and neck

$639,614
Dong Moon Shin · Emory University · R01 · FY2024 · CA

Strategies for Cancer Immunotherapy Clinical Trials

$639,565
Jeffrey Schlom · Division Of Basic Sciences - Nci · ZIA · FY2023 · CA

Strategies for Therapeutic Cancer Vaccine Clinical Trials

$639,402
Jeffrey Schlom · Division Of Basic Sciences - Nci · ZIA · FY2014 · CA

Combinations of Receptor-Targeted Alpha Radionuclide Therapy and Immune Checkpoint Inhibitors for Melanoma Treatment

$639,351
Yubin Miao · University Of Colorado Denver · R01 · FY2023 · CA

First in Class Small molecules to simultaneously inhibit protein translation and an immune checkpoint in cancers

$639,330
France Carrier · University Of Maryland Baltimore · R01 · FY2024 · CA

First in Class Small molecules to simultaneously inhibit protein translation and an immune checkpoint in cancers

$639,330
France Carrier · University Of Maryland Baltimore · R01 · FY2025 · CA

Serial immunotherapy combination to modulate the tumor environment in patients with metastatic gastroesophageal cancer

$639,268
Harry H Yoon · Mayo Clinic Rochester · R01 · FY2022 · CA

Mechanisms of BET bromodomain metabolic reprogramming in triple negative breast cancer

$639,256
Gerald V Denis · Boston University Medical Campus · R01 · FY2020 · CA

A phase I/II study of combined therapy with Th17-inducing dendritic cells and pembrolizumab in patients with recurrent epithelial ovarian cancer

$639,109
Keith L Knutson · Mayo Clinic Jacksonville · R01 · FY2025 · CA

A model for predicting response to PD-1 inhibitors in NSCLC

$639,083
Edward B Garon · University Of California Los Angeles · R01 · FY2017 · CA

A physical sciences approach to investigate the role of exosomes in metastatic progression

$639,040
Ravi Radhakrishnan · University Of Pennsylvania · U01 · FY2024 · CA

NT-I7, a novel long-acting interleukin-7, in combination with anti-PD-1 checkpoint blockade for the treatment of glioablastoma

$639,004
Jian Campian · Mayo Clinic Rochester · R01 · FY2025 · CA

A novel preclinical model of spontaneous metastasis

$638,924
Glenn T. Merlino · Division Of Basic Sciences - Nci · ZIA · FY2015 · CA

Understanding the role of autophagy-regulated cell death in the escape from replicative crisis

$638,770
Jan Karlseder · Salk Institute For Biological Studies · R01 · FY2021 · CA

Understanding the role of autophagy-regulated cell death in the escape from replicative crisis

$638,770
Jan Karlseder · Salk Institute For Biological Studies · R01 · FY2020 · CA

Identification of pathways to mitigate Immune-Related Adverse Events with Cancer Immunotherapy

$638,608
Donald Ym Leung · National Jewish Health · U01 · FY2020 · AR