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15,440 grants matching organoids

Cell-type-specific NRXN1alpha alternative splicing changes in psychiatric disease

$809,441
Kristen Jennifer Brennand · Icahn School Of Medicine At Mount Sinai · R01 · FY2020 · MH

Identifying Factors Regulating Medium Spiny Neuron Differentiation or Maintenance as Therapeutic Targets for Huntington's Disease using Induced Pluripotent Stem Cells

$809,186
Lisa M. Ellerby · Buck Institute For Research On Aging · R01 · FY2024 · NS

Regulation of HIV latency by microglial-neuronal interactions

$807,952
Jonathan Karn · Case Western Reserve University · R01 · FY2019 · DA

An Intrinsic Link between the Metabolic and Antiviral States of the Cell

$807,943
Alex Compton · Division Of Basic Sciences - Nci · ZIA · FY2025 · CA

Systematic identification of oncogenic KRAS synthetic lethal interactions

$807,776
William C Hahn · Broad Institute, Inc. · U01 · FY2017 · CA

Systematic identification of oncogenic KRAS synthetic lethal interactions

$807,776
William C Hahn · Broad Institute, Inc. · U01 · FY2016 · CA

Systematic identification of oncogenic KRAS synthetic lethal interactions

$807,776
William C Hahn · Broad Institute, Inc. · U01 · FY2018 · CA

Mass spectrometry and multiplexed immunofluorescence imaging of metabolic and proteomic contributors to selective neuronal vulnerability in Alzheimer's disease

$807,254
Merina Thekenangarpadiyil Varghese · University Of Rhode Island · R01 · FY2025 · AG

Skin microbiome contributions to the pathogenesis of cutaneous leishmaniasis

$807,175
Phillip A. Scott · University Of Pennsylvania · R01 · FY2024 · AI

Polymerase Inhibitors of Respiratory Syncytial Virus

$806,958
Richard K. Plemper · Georgia State University · R01 · FY2020 · AI

Mapping gut-spinal cord connections in visceral pain

$806,943
David J Julius · University Of California, San Francisco · U01 · FY2019 · NS

Longitudinal models of breast cancer for studying mechanisms of therapy response and resistance

$806,283
Bryan E. Welm · University Of Utah · U01 · FY2022 · CA

Defining the KRAS mutation specific interactions in pancreas cancer

$806,129
Guy Hobbs · Medical University Of South Carolina · P20 · FY2023 · GM

Pericyte contribution to capillary remodeling in pulmonary arterial hypertension

$806,127
Ke Yuan · Boston Children'S Hospital · R01 · FY2024 · HL

Sphingolipid Biology of Neurodegeneration

$805,719
Richard Proia · National Institute Of Diabetes And Digestive And Kidney Diseases · ZIA · FY2020 · DK

Skin microbiome contributions to the pathogenesis of cutaneous leishmaniasis

$805,550
Phillip A. Scott · University Of Pennsylvania · R01 · FY2025 · AI

Innate Immune Regulation of Zika Virus Infection

$805,011
Michael J Gale · University Of Washington · R01 · FY2021 · AI

Cross modal integration of molecular and physiological networks in ASD (2/2)

$804,886
Sergiu Pasca · Stanford University · U01 · FY2018 · MH

Structure and Function of C. Difficile Toxins

$804,015
Min Dong · Boston Children'S Hospital · R01 · FY2020 · AI

Role of intestinal microfold (M) cells in creating a hotspot environment for HIV reservoir persistence and reactivation

$803,777
German Gustavo Gornalusse · University Of Washington · R01 · FY2025 · AI

MECHANISMS OF VISCERAL PAIN DRIVEN BY SMALL INTESTINAL MICROBIOTA

$803,109
Purna C Kashyap · Mayo Clinic Rochester · R01 · FY2025 · DK

Therapeutic targets and novel anticancer agents for endocrine cancers

$802,871
Naris Nilubol · Division Of Basic Sciences - Nci · ZIA · FY2024 · CA

Interpreting coding/non-coding variants for congenital heart disease through gene regulatory networks

$802,762
Gary Chung Hon · Ut Southwestern Medical Center · R01 · FY2025 · HL

Project II: Immune regulatory circuits in primary colon cancer and lymph node and liver metastases

$802,523
Alexander Y. Rudensky · Sloan-Kettering Inst Can Research · U54 · FY2024 · CA

A mechanistic 3D AI-powered map of genetic chILD

$802,500
Yan Xu · Cincinnati Childrens Hosp Med Ctr · U01 · FY2025 · HL