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24,576 grants matching “microbiome”
Microbiome-host interactions in oral squamous cell carcinoma: a meta-transcriptomic exploratory study
$175,413Nezar Al-Hebshi · Temple Univ Of The Commonwealth · R03 · FY2020 · DE
W-Health: Tungsten is an Essential Metal for a Healthy Gut Microbiome
$175,370Michael W. Adams · University Of Georgia · R01 · FY2021 · GM
TransBiota: Genital microbiome, inflammation and HIV risk in trans men and women
$175,338Jacques Ravel · University Of Maryland Baltimore · R21 · FY2023 · AI
Collaborative research: Physiological signatures of variable weaning strategies in wild primates
$175,306Laurie Reitsema · University Of Georgia Research Foundation Inc · · FY2017 · SBE
BEES ARE CRUCIAL POLLINATORS WHO ARE BEINGEXPOSED TO HARMFUL AGRICULTURAL CHEMICALS (E.G. PESTICIDES AND FUNGICIDES) IN BOTH NECTAR AND POLLEN OF CROPS AND WILDFLOWERS. THESE CHEMICALS HAVE BROAD IMPACTS ON POLLINATOR HEALTH, BUT THEIR IMPACTS ON BEE AND PLANT MICROBIOMES REMAIN POORLY UNDERSTOOD. THE MICROBES FOUND IN BEE'S DIGESTIVE TRACT AND INSIDE FLOWERS ARE CRITICAL FOR CERTAIN ASPECTS OF BEE HEALTH (SUCH AS DIGESTION AND PROTECTION AGAINST PARASITES) AND CAN EVEN INFLUENCE THE WAY BEES INTERACT WITH PLANTS. IN AGRICULTURAL ECOSYSTEMS, PLANTS ARE OFTEN TREATED WITH MULTIPLE CHEMICALS, AND THERE IS A CRITICAL KNOWLEDGE GAP REGARDING HOW COMBINATIONS OF AGROCHEMICALS ALTER FLORAL AND BEE MICROBIAL COMMUNITIES IN WAYS THAT ARE MEANINGFUL TO EITHER PARTY. I WILL COMBINE LAB AND FIELD-BASED APPROACHES TO ASSESS WHETHER PESTICIDES, FUNGICIDES, AND THEIR COMBINATION ALTER 1) THE WILD BUMBLE BEE MICROBIOME 2) THE FLORAL MICROBIOME 3) PLANT-POLLINATOR INTERACTIONS AND 4) LANDSCAPE-LEVEL PATTERNS IN FLORAL MICROBES. TO ACCOMPLISH THIS, I WILL DOSE WILD-CAUGHT BUMBLE BEES AND TREAT FLORAL MICROBES WITH A COMMON PESTICIDE, FUNGICIDE, AND THEIR COMBINATION TO QUANTIFY CHANGES IN MICROBIAL COMMUNITIES. THEN, I WILL COMPARE HOW THE SAME CHEMICAL TREATMENTS AFFECT THE FLORAL MICROBIOME AND REPRODUCTIVE SUCCESS OF A PLANT COMMONLY FOUND IN AGRICULTURAL MARGINS, PENSTEMON. FINALLY, I WILL COMPARE FLORAL MICROBIAL COMMUNITIES IN PENSTEMON PLANTS SAMPLED ALONG A GRADIENT OF POTENTIAL EXPOSURE TO AGRICULTURAL CHEMICALS. THESE PLANTS ARE OFTEN RECOMMENDED AS PART OF POLLINATOR-FRIENDLY PLANTINGS IN AGRICULTURAL FIELDS AND URBAN ENVIRONMENTS, AND IT WILL BE INSIGHTFUL TO KNOW HOW THEIR MICROBIAL COMMUNITIES ARE ALTERED BY EXPOSURE TO AGRICULTURAL CHEMICALS. GIVEN RECENT UNDERSTANDING OF HOW IMPORTANT MICROBES ARE TO BOTH POLLINATOR HEALTH AND PLANT PRODUCTIVITY, UNDERSTANDING HOW AGRICULTURAL CHEMICAL COMPLEXITY CAN ALTER BEE-MICROBE-PLANT INTERACTIONS IS A PRESSING QUESTION FOR MAINTAINING HEALTHY POLLINATORS IN AGRICULTURAL ECOSYSTEMS.
$175,222Board Of Regents Of Nevada System Of Higher Education · · FY2022 · National Institute of Food and Agriculture
Modulating the Microbiome to Enhance Right Ventricular Function in Pulmonary Arterial Hypertension
$175,068Sasha Zheng Prisco · University Of Minnesota · K08 · FY2024 · HL
Modulating the Microbiome to Enhance Right Ventricular Function in Pulmonary Arterial Hypertension
$175,068Sasha Zheng Prisco · University Of Minnesota · K08 · FY2025 · HL
Molecular Mechanisms of Organelle Formation in Bacteria
$175,033Arash Komeili · University Of California Berkeley · R35 · FY2022 · GM
Computational Data Analysis Core
$175,011Junguk Hur · University Of North Dakota · P20 · FY2024 · GM
Gut Microbiome Profiles in Association with Breast Cancer Recurrence and Mortality
$175,000Sang Minh Nguyen · Vanderbilt University Medical Center · R03 · FY2024 · CA
The Microbiome in Mammary Development, and Lacatation
$175,000Darryl L Hadsell · Baylor College Of Medicine · R21 · FY2019 · HD
Administrative Supplement: Model-guided design of next-generation bacterial therapeutics to treat cardiovascular disease
$175,000Ophelia Venturelli · University Of Wisconsin-Madison · R01 · FY2023 · EB
Statistical Frameworks for Self-Supervised Representation Learning and Their Biomedical Applications
$175,000Shulei Wang · University Of Illinois At Urbana-Champaign · · FY2025 · MPS
A study of antibiotics usage on early gut microbiome colonization and establishment in young children
$174,991Weizhong Li · J. Craig Venter Institute, Inc. · R21 · FY2021 · AI
Innovative 3D Printed Intravaginal Ring AnelleO-PRO, the first Single Administration of Progesterone for Infertility
$174,975Soumya Rahima Benhabbour · Anelleo, Inc. · R41 · FY2019 · HD
Nasal Microbiome and Host Immunity in Granulomatosis with Polyangiitis
$174,962Rennie Rhee · University Of Pennsylvania · K23 · FY2017 · AR
Data and Omics Sciences Core
$174,927Luis R Pericchi · University Of Puerto Rico Med Sciences · U54 · FY2021 · CA
Pilot Project 1: Combination of Viroimmunotherapy and Microbiota Modulation to Treat Gastric Cancer
$174,927Filipa Godoy-Vitorino · University Of Puerto Rico Med Sciences · U54 · FY2021 · CA
High-resolution mutational landscape of the primed colon in early onset colorectal cancer
$174,911William M Grady · Fred Hutchinson Cancer Center · U54 · FY2023 · CA
Molecular Biomarkers of Improvement for Patients with Systemic Sclerosis in an Open Label Trial of Mycophenolate Mofetil
$174,900Michael L Whitfield · Dartmouth College · R21 · FY2016 · AR
GEI - Genome-Wide Association Studies
$174,823Neil E. Caporaso · Division Of Cancer Epidemiology And Genetics · ZIA · FY2015 · CA
Malassezia and Candida auris: skin microbiome dysbiosis and de-regulation of cutaneous homeostasis
$174,750Joseph Heitman · Duke University · R21 · FY2024 · AI
Culturing Uncultivatable Gut Microorganisms
$174,715Kim Lewis · Northeastern University · R01 · FY2011 · HG
Collaborative Clinical Research on Non Alcoholic Stratohepatitis
$174,712Naga P. Chalasani · Indiana University Indianapolis · U01 · FY2015 · DK
Diversity of the Mosquito Microbiota and its Influence on Pathogen Transmission
$174,670Matthew C I Medeiros · University Of Hawaii At Manoa · P20 · FY2021 · GM