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24,576 grants matching “microbiome”
Nutritional strategies for metabolic health in aging
$193,360Robert H Coker · University Of Alaska Fairbanks · P20 · FY2021 · GM
Training Program in Immunology and Inflammation
$193,358Boris Reizis · New York University School Of Medicine · T32 · FY2016 · AI
A PRECLINICAL MODEL OF ALCOHOLIC HEPATITIS
$193,355Arun J Sanyal · Virginia Commonwealth University · UH2 · FY2019 · AA
Biogeography of Aquatic Pathogens in Hawaiian Watersheds
$193,299Kiana Frank · University Of Hawaii At Manoa · P20 · FY2020 · GM
Microbiome / Gnotobiotic Shared Facility
$193,297Casey D Morrow · University Of Alabama At Birmingham · P30 · FY2020 · CA
Bioinformatics Core: Core C
$193,233Rafick-Pierre Sekaly · Drexel University · U19 · FY2021 · AI
Fluorescence Lifetime Imaging (FLIm): a method to evaluate colon inflammation in vivo
$193,200Alba Alfonso-Garcia · University Of California At Davis · R21 · FY2024 · DK
HBD-3: A novel factor orchestrating microbial persistence in suspicious oral lesions
$193,135Aaron Weinberg · Case Western Reserve University · R21 · FY2020 · DE
Role of short chain fatty acids in intestinal barrier maturation in preterm infants
$193,125Bing Ma · University Of Maryland Baltimore · R21 · FY2020 · DK
Mucosal immune biomarkers to detect neonatal leaky gut
$193,125Bing Ma · University Of Maryland Baltimore · R21 · FY2024 · HD
Identification of the gene encoding lipid A deacylase, an enzyme required for TLR4-evasion, in Porphyromonas gingivalis
$193,125Richard Peters Darveau · University Of Washington · R21 · FY2017 · DE
Functional characterization of IL-40, a novel cytokine
$193,125Albert Zlotnik · University Of California-Irvine · R21 · FY2016 · AI
Comprehensive Characterization of Intestinal Parasites in Infants and Their Impact on Diarrhea
$193,125David Serre · University Of Maryland Baltimore · R21 · FY2020 · AI
Phylogenetic Binning of Metagenomic Sequence Data
$193,125Eric Ellsworth Allen · University Of California, San Diego · R21 · FY2010 · HG
Communicating Clocks: Unraveling the nutritional link between the gut microbiome and liver reprogramming
$193,125Paolo Sassone-Corsi · University Of California-Irvine · R21 · FY2018 · DK
The Candida albicans commensal program
$193,125Suzanne M Noble · University Of California, San Francisco · R21 · FY2012 · AI
Collaborative Research: Characterization of the Microbiome Aerosolized in Shower Units
$193,033Maria D King · Texas A&M Engineering Experiment Station · · FY2012 · ENG
Metabolic and Microbiome Mechanisms Linking Gestational Phthalate Exposure with Child ASD Risk
$193,000Cheryl Katherine Walker · University Of California At Davis · R21 · FY2018 · ES
**AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** OBESITY IS A CHRONIC PROGRESSIVE DISEASE THAT LEADS TO THE DEVELOPMENT OF TYPE 2 DIABETES, HEART DISEASE, AND STROKE, ALL OFWHICH ARE AMONG THE TOP 10 LEADING CAUSES OF DEATH IN THE U.S. CURRENTLY, LIFESTYLE MODIFICATION, INCLUDING DIET, EXERCISE, ANDBEHAVIOR THERAPY, HAS REMAINED THE FIRST OPTION TO EFFECTIVELY AND SAFELY CONTROL THE PROGRESSION OF OBESITY AND OBESITY-RELATEDDISEASES. HOWEVER, LOW ADHERENCE TO LIFESTYLE INTERVENTIONS UNDERSCORES THE URGENCY TO DEVELOP OTHER STRATEGIES TO COMBATOBESITY. WE ARE THE FIRST RESEARCH GROUP TO INVESTIGATE THE NUTRACEUTICAL VALUES OF DIETARY EXOSOME-LIKE NANOPARTICLES (ELNS) INOBESITY. WE FOUND THAT CHIVE-DERIVED ELNS (C-ELNS) IMPROVE METABOLIC HEALTH IN DIET-INDUCED OBESE MICE. CONTINUING ALONGTHIS LINE OF RESEARCH, IN THIS PROJECT WE WILL INVESTIGATE (1) THE BIOAVAILABILITY AND DISTRIBUTION OF C-ELNS IN VIVO; (2) ABSORPTION OFC-ELNS IN INTESTINAL EPITHELIAL CELLS; AND (3) THE IMPACT OF C-ELNS ON THE GUT MICROBIOME IN OBESITY. SUCCESSFUL COMPLETION OFTHE PROPOSED RESEARCH WILL PROVIDE MECHANISTIC INSIGHTS INTO HOW C-ELNS DISTRIBUTE AND FUNCTION IN VIVO AND PAVE THE WAY FORAPPLYING C-ELNS TO COMBAT OBESITY.
$192,973Case Western Reserve University · · FY2024 · National Institute of Food and Agriculture
A prospective, longitudinal perspective on gut microbiome aging and health in a non-human primate model
$192,936Elizabeth Archie · University Of Notre Dame · R21 · FY2018 · AG
Ingestible Pill for spatially targeted sampling of gut microbiome
$192,915Sameer R Sonkusale · Tufts University Medford · R21 · FY2023 · DK
Spatio-temporal mechanistic modeling of whole-cell tumor metabolism
$192,844Daniel Segre · Boston University (Charles River Campus) · R21 · FY2023 · CA
Enterolactone and asthma
$192,839Juan Carlos Cardet · University Of South Florida · K23 · FY2018 · AI
Enterolactone and asthma
$192,839Juan Carlos Cardet · University Of South Florida · K23 · FY2019 · AI
Enterolactone and asthma
$192,839Juan Carlos Cardet · University Of South Florida · K23 · FY2020 · AI