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10,766 grants matching checkpoint inhibitor

Targeting the Mitochondria to Overcome Resistance to Immune Checkpoint Inhibition in Malignant Pleural Mesothelioma

$659,626
Robert Taylor Ripley · Baylor College Of Medicine · R37 · FY2025 · CA

A physical sciences approach to investigate the role of exosomes in metastatic progression

$659,220
Ravi Radhakrishnan · University Of Pennsylvania · U01 · FY2023 · CA

A physical sciences approach to investigate the role of exosomes in metastatic progression

$659,220
Ravi Radhakrishnan · University Of Pennsylvania · U01 · FY2022 · CA

Mutant KRAS targeted vaccines for the interception of pancreatic cancer development

$659,090
Neeha Zaidi · Johns Hopkins University · R37 · FY2025 · CA

Mutant KRAS targeted vaccines for the interception of pancreatic cancer development

$659,090
Neeha Zaidi · Johns Hopkins University · R37 · FY2024 · CA

Mechanism of LSD1 Function and Its Therapeutic Application for Progressive Oral Malignancy

$659,051
Manish Bais · Boston University Medical Campus · R01 · FY2023 · DE

Molecular, Cellular and Genetic Analyses of Malignancies Associated with NF1

$659,046
Karlyne M Reilly · Division Of Basic Sciences - Nci · ZIA · FY2021 · CA

Epigenetic Therapy for Thoracic Malignancies

$658,967
David Schrump · Division Of Clinical Sciences - Nci · ZIA · FY2020 · CA

SynerGel: A Novel Tumor Microenvironment-Modulating Hydrogel for Local Immunotherapy

$658,892
Simon Young · University Of Texas Hlth Sci Ctr Houston · R01 · FY2023 · DE

[18F]F-AraG as an imaging biomarker for early diagnosis and monitoring of cardiotoxicity related to doxorubicin and immune check point inhibitor therapy

$658,891
Youngho Seo · University Of California, San Francisco · R01 · FY2025 · HL

Remodeling Chromatin and the Tumor Microenvironment: Direct Oncogenesis and Therapeutic Targeting

$658,720
David E Fisher · Massachusetts General Hospital · P01 · FY2024 · CA

Ultrasmall particle-based solutions for inducing ferroptosis and improving anti-tumor immune responses in cancer

$658,454
Michelle S Bradbury · Sloan-Kettering Inst Can Research · R01 · FY2020 · CA

Biological and social determinants of psychosocial sequelae in advanced head and neck cancer survivors receiving immunotherapy

$658,403
Canhua Xiao · Emory University · R01 · FY2025 · CA

The Impact of Metastatic Site On Dendritic Cell-Driven Tumor Immunity

$658,369
David G Denardo · Washington University · U01 · FY2023 · CA

Radioimmunogenomic Habitat Phenotypes to Predict Efficacy of Neoadjuvant Immunotherapies in Non-Small Cell Lung Cancer

$658,205
Jia Wu · University Of Tx Md Anderson Can Ctr · R01 · FY2023 · CA

Targeting novel therapeutic vulnerabilities in LKB1 mutant tumors.

$657,955
Nabeel Bardeesy · Massachusetts General Hospital · R01 · FY2019 · CA

Immunotherapy Modeling in Organoids Co-preserving Tumor and Infiltrating Immune Compartments

$657,944
Calvin J Kuo · Stanford University · R01 · FY2021 · CA

Generation of tumor specific immunity in canine osteosarcoma through dendritic cell hyperactivation

$657,791
Cheryl A London · Tufts University Boston · U01 · FY2023 · CA

Targeting head and neck cancer cells and the adverse tumor microenvironment with a novel small-molecule STAT3 inhibitor

$657,573
David John Tweardy · University Of Tx Md Anderson Can Ctr · R01 · FY2023 · CA

Targeting natural killer cells to enhance HIV vaccine responses

$657,254
Stephen N. Waggoner · Cincinnati Childrens Hosp Med Ctr · R01 · FY2021 · AI

Chemokine-mediated antigen-specific T cell responses and immunotherapies to treat head and neck cancer

$657,132
Dohun Pyeon · Michigan State University · R01 · FY2021 · DE

Integrating patient-reported outcomes and T-cell receptor sequencing to predict immune-related adverse events

$657,119
Aung Naing · University Of Tx Md Anderson Can Ctr · R01 · FY2025 · CA

Integrating patient-reported outcomes and T-cell receptor sequencing to predict immune-related adverse events

$657,119
Aung Naing · University Of Tx Md Anderson Can Ctr · R01 · FY2024 · CA

Mechanisms of JAG1-mediated immune suppression in the pancreatic cancer microenvironment

$657,074
Lan Zhou · Methodist Hospital Research Institute · R01 · FY2025 · CA

Mechanisms of Nucleic Acid Enzymes - Pol Beta, HIV-1 Reverse Transcriptase and Mammalian Base Repair Enzymes

$657,042
Samuel H Wilson · National Institute Of Environmental Health Sciences · ZIA · FY2021 · ES