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17,828 grants matching “crispr”
The dynamics and impact of R-loops in epigenetic stability and aging
$32,482Henry Miller · University Of Texas Hlth Science Center · F31 · FY2021 · AG
Muscle-Specific CRISPR/Cas9 Exon Skipping for Duchenne Muscular Dystrophy Therapeutics
$32,478Carolyn Kraus · Univ Of Massachusetts Med Sch Worcester · F31 · FY2023 · AR
Mechanism of cell lethality following loss of gene expression.
$32,478Nicholas Wade Harper · Univ Of Massachusetts Med Sch Worcester · F31 · FY2023 · CA
Establishing and Optimizing a Prime Editing Method in Neurons for Treatment of Rett Syndrome
$32,460David G. Keener · Univ Of Massachusetts Med Sch Worcester · F31 · FY2023 · NS
Activation of non-apoptotic cell death by the DNA damage response
$32,448Megan Elizabeth Honeywell · Univ Of Massachusetts Med Sch Worcester · F31 · FY2023 · CA
Systematic mapping and prediction of gene-enhancer connections
$32,400Jesse M Engreitz · Broad Institute, Inc. · K99 · FY2019 · HG
Elucidating how a USP9X-COP1 axis regulates RIT1 protein abundance and reveals druggable targets in lung adenocarcinoma
$32,382Amanda Riley · Fred Hutchinson Cancer Center · F31 · FY2023 · CA
Single nucleotide variations account for strain specific virulence changes in Cryptococcus neoformans
$32,363Katrina M Jackson · University Of Minnesota · F31 · FY2021 · AI
Targeting a Novel Pocket on ITGAV
$32,342Nicole Mattson · Beckman Research Institute/City Of Hope · F99 · FY2022 · CA
Site-Specific Correction of Sickle Cell Disease Using Acoustofludic Gene Delivery
$32,340Jason Nathaniel Belling · University Of California Los Angeles · F31 · FY2020 · HL
Dosage Sensitivity of Gene Expression in Pluripotent Stem Cells in the context of Down Syndrome
$32,329Jennifer Eun-Mi Moon · Univ Of Massachusetts Med Sch Worcester · F31 · FY2019 · HD
Amelioration of Beta-hemoglobinopathies by efficient precise deletion of the +58 BCL11A enhancer using orthogonal Cas9-Cas9 chimeras
$32,329Kevin Luk · Univ Of Massachusetts Med Sch Worcester · F31 · FY2019 · HL
Metabolic alterations contributing to enzalutamide resistance in prostate cancer
$32,302Eliot Blatt · Ut Southwestern Medical Center · F31 · FY2022 · CA
Control of the MYC Super-Enhancer Complex in FLT3-ITD Acute Myeloid Leukemia
$32,248William Montgomery Yashar · Oregon Health & Science University · F30 · FY2024 · CA
Mechanisms of Transcriptional Regulation by MTG16 in the Intestine
$32,152Rachel Elizabeth Brown · Vanderbilt University · F30 · FY2020 · DK
Characterizing the role of MINK1 in Congenital Heart Disease and mucociliary clearance
$32,148Vaughn Colleluori · Yale University · F31 · FY2020 · HL
Identifying Novel Target Pathways and Therapies in Castration Resistant Prostate Cancer
$32,124Marisa Sanchez · Sanford Burnham Prebys Medical Discovery Institute · F31 · FY2018 · CA
Investigating molecular mechanism of T cell exhaustion in chronic infection and tumor microenvironment
$32,106Zeyu Chen · University Of Pennsylvania · F99 · FY2019 · CA
Aberrant Splicing in the Cardiac Arrhythmias
$32,007Matthew O'Neill · Vanderbilt University · F30 · FY2022 · HL
The APOBEC in APOBEC mutagenesis
$31,973Matthew C Jarvis · University Of Minnesota · F31 · FY2021 · CA
Mechanism of CD8 regulation of natural killer cell biology
$31,970Celia Claire Cubitt · Washington University · F30 · FY2021 · AI
Elucidating the Role of Noradrenergic Circuitry in Aversive Contextual Processing
$31,847Eric Zhang · University Of Washington · F31 · FY2023 · MH
Dosage Sensitivity of Gene Expression in Pluripotent Stem Cells in the context of Down Syndrome
$31,837Jennifer Eun-Mi Moon · Univ Of Massachusetts Med Sch Worcester · F31 · FY2018 · HD
Impact of RNA splicing factor mutations on circular RNA biogenesis in leukemia
$31,784Mike Fernandez · Beckman Research Institute/City Of Hope · F31 · FY2023 · CA
Functional interrogation of a novel SCGB3A2+/SFTPB+ cell in the human airway
$31,745Jason Spence · University Of Michigan At Ann Arbor · R01 · FY2024 · HL