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17,828 grants matching “crispr”
Infectious cell entry pathway of human-infecting thogotoviruses
$34,515Paul William Rothlauf · Harvard Medical School · F31 · FY2022 · AI
Elucidating mechanisms of ATXN2 interaction with TDP-43 in human motor neuron models of Amyotrophic Lateral Sclerosis
$34,515Stanley Pernell Gill · Harvard Medical School · F31 · FY2022 · NS
Intratumoral plasma cells in MPNST response to CDK4/6 targeted therapy and sensitization to immune checkpoint blockade
$34,491Joshua J Lingo · University Of Iowa · F31 · FY2023 · CA
Identifying targets for combination therapy with FOLFIRINOX and investigating cell polarity loss as a potential driver of invasion in basal-like PDAC
$34,454Sandra Zarmer · Univ Of North Carolina Chapel Hill · F31 · FY2021 · CA
Identifying and targeting the genetic determinants of immune suppression and immunotherapy failure in prostate cancer.
$34,454Katherine C. Murphy · Univ Of Massachusetts Med Sch Worcester · F31 · FY2025 · CA
The Determinants of CD8 T cell Dysfunction in Oral Cavity Squamous Cell Carcinoma
$34,446Riley Dalton Zale Mullins · Washington University · F31 · FY2023 · DE
A single prime editing strategy for correcting diverse mutations responsible for RBM20-associated dilated cardiomyopathy
$34,370Nicholas Gaston · Univ Of Massachusetts Med Sch Worcester · F31 · FY2025 · HL
Developing a novel adenine base editor tool for in vivo alpha-1 antitrypsin deficiency gene correction.
$34,344Jenny Gao · Univ Of Massachusetts Med Sch Worcester · F30 · FY2025 · HL
Tracing mechanisms of cellular heterogeneity and drug resistance in cancer
$34,337Gabriel Lee Eades · University Of California, San Francisco · F32 · FY2016 · CA
Evaluating the role of Mecr and Mitochondrial Fatty Acid Synthesis in T cell Function and Metabolism
$34,314Kaylee Kristal Steiner · Vanderbilt University · F31 · FY2024 · DK
Uncovering functional nodes of the Rett syndrome transcriptome
$34,290Daniel Connolly · University Of Pennsylvania · F30 · FY2022 · HD
Assessing Sox 10's effect on chromatin accessibility in enteric neuron lineage diversification
$34,250Joseph T Benthal · Vanderbilt University · F31 · FY2024 · DK
Exploring cyclic di-nucleotide signaling across the tree of life (Supplement)
$34,246Christopher M Waters · Michigan State University · R35 · FY2024 · GM
Identification and Characterization of the Antiviral Response to RSV Infection: A Single Cell Approach
$34,217Sara Sunshine · University Of California, San Francisco · F31 · FY2022 · AI
Characterizing ALCAM as an oncoprotein and immunotherapeutic target in neuroblastoma
$34,204Jarrett Lindsay · University Of Pennsylvania · F31 · FY2022 · CA
Gene Therapy for the Treatment of Neurofibromatosis Type I (NF1)
$34,190Madeleine Janette Sitton · Duke University · F99 · FY2023 · CA
Metabotropic contributions to pH-sensitivity and breathing modulation by RTN chemoreceptors
$34,182Elizabeth Catherine Gonye · University Of Virginia · F31 · FY2020 · HL
Defining the function of SETD8 in colorectal cancer
$34,179Zvi Cramer · University Of Pennsylvania · F31 · FY2022 · CA
Mechanistic dissection of novel regulators of TDP-43 aggregation identified in a genome-wide CRISPR-Cas9 knockout screen
$34,179Katelyn Sweeney · University Of Pennsylvania · F31 · FY2022 · NS
Coupling a multifunctional tag to scalable endogenous tagging technology for improved genome-wide perturbation screens
$34,179Stephanie Elizabeth Sansbury · University Of Pennsylvania · F31 · FY2022 · HG
Deciphering the contribution of enhancer transcription to enhancer function
$34,127Carlos Guzman · University Of California, San Diego · F31 · FY2023 · HG
Lineage Analysis of Cellular States Predicting Reprogramming into iPSCs
$34,096Naveen Jain · University Of Pennsylvania · F30 · FY2022 · HD
High Frequency of CHD1 Loss in BRCA2- Deficient African American Prostate Tumors Drives Tumor Formation by Suppressing Replication Stress
$34,092Zoltan Szallasi · Dana-Farber Cancer Inst · U54 · FY2022 · CA
The Oncogenic functions of YAP/TAZ in Renal Cell Carcinoma
$34,052Alec Thomas McIntosh · Georgetown University · F30 · FY2022 · CA
Genetically inducible cell sorting to interrogate human pluripotent stem cell lineage transitions
$34,037Ashley Libby · University Of California, San Francisco · F31 · FY2019 · HL