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24,576 grants matching microbiome

Integrative Analysis of the Blood Plasma and Tumor Microbiome: A Novel Approach to Liquid Biopsy Screening for Early Epithelial Ovarian Cancer Detection

$224,840
Diane E Mahoney · University Of Kansas Medical Center · P20 · FY2024 · GM

INTENSIVE AGRICULTURAL PRODUCTION HAS LED TO HIGH AMOUNTS OF CARBON LOSS FROM THE SOIL. HOWEVER, ALTERNATIVE MODELS OF AGRICULTURAL PRODUCTION THAT MANAGE FOR BIODIVERSITY OVER BOTH SPACE AND TIME, SUCH AS COFFEE AGROFORESTRY SYSTEMS, CAN SERVE TO INCREASE CARBON STORAGE IN THE SOIL THROUGH CHANGES IN THE SOIL MICROBIOME. YET, UNDERSTANDING OF CARBON FORMATION IN THE SOIL IN AGRICULTURAL SYSTEMS IS STILL LIMITED, AND RECENT STUDIES SUGGEST THAT PLANT PHOTOSYNTHESIS AND DOWNSTREAM EFFECTS ON SOIL BIOLOGY ARE THE LIMITING FACTOR OF CARBON SEQUESTRATION. ARBUSCULAR MYCORRHIZAL FUNGI (AMF), SOIL BORN FUNGI THAT FORM ASSOCIATIONS WITH PLANT ROOTS, REDISTRIBUTE CARBON PRODUCED BY PLANTS INTO THE SOIL. THE CARBON FROM THE PLANTS IS THEN EITHER METABOLIZED BY SOIL BACTERIA, OR STORED AS CARBON IN THE SOIL. HOWEVER, THE EFFECTS OF CANOPY COVER IN AGROFORESTRY SYSTEMS ON PLANT PHOTOSYNTHESIS, AMF, AND ASSOCIATED SOIL BIOGEOCHEMICAL MECHANISMS REMAIN UNDERSTUDIED. THIS PROJECT WILL EXAMINE HOW GRADIENTS OF SHADE IN COFFEE AGROFORESTRY SYSTEMS IN HAWAI'I CHANGE AMF COMMUNITIES AND ASSOCIATED SOIL BIODIVERSITY, AND IN TURN MICROBIAL PROCESSING OF ORGANIC MATTER AND SOIL CARBON USING FIELD OBSERVATIONAL STUDIES. THE STUDY ALSO INCLUDES A PAIRED GREENHOUSE EXPERIMENT TO EXAMINE THE FEEDBACK OF SOIL BIOLOGY TO PLANT HEALTH AND ASSOCIATED CARBON UNDER DIFFERENT SHADE TREATMENTS. THIS RESEARCH WILL EXPAND THE UNDERSTANDING OF THE ROLE OF PHOTOSYNTHESIS AND ASSOCIATED SOIL BIOLOGY IN CARBON STORAGE IN AGROFORESTRY SYSTEMS, WHICH IS CRITICAL FOR CREATING SUSTAINABLE AGRICULTURAL SYSTEMS.

$224,809
Regents Of The University Of California, The · · FY2025 · National Institute of Food and Agriculture

Sphingolipid-dependent host-microbe interactions

$224,807
Elizabeth L Johnson · Cornell University · R35 · FY2021 · GM

TransBiota: Genital microbiome, inflammation and HIV risk in trans men and women

$224,775
Jacques Ravel · University Of Maryland Baltimore · R21 · FY2022 · AI

Integrated and universal ultrasonic microbial lysis and extraction

$224,669
Gregory John Kellogg · Covaris, Inc. · R43 · FY2019 · GM

Characterization of the Impact of the Noncapped Alphavirus Genomic RNAs

$224,648
Kevin Joseph Sokoloski · University Of Louisville · P20 · FY2020 · GM

Novel Re-engineered L DOPA probiotic therapy for Parkinsons Disease

$224,584
Anumantha Gounder Kanthasamy · Iowa State University · R61 · FY2020 · NS

Dartmouth Cystic Fibrosis Training Program

$224,496
George A. O'Toole · Dartmouth College · T32 · FY2024 · HL

Core C: Biostatistics and Bioinformatics Core

$224,479
Li Hsu · Fred Hutchinson Cancer Center · P50 · FY2024 · CA

HIV Microbicides and the Vaginal Microbiome

$224,465
Steven L. Zeichner · Children'S Research Institute · R21 · FY2009 · AI

Novel treatment for Crohn's disease and related inflammatory gastrointestinal disease

$224,412
Stacy Marie Townsend · Synedgen, Inc. · R43 · FY2016 · DK

Project 4: Impact of the Gut Microbiome on Liver Innate Immunity and Skeletal Function

$224,250
Chad Michael Novince · Medical University Of South Carolina · P20 · FY2020 · GM

Hydra as an Antiviral Innate Immunity Model System

$224,250
Forest L Rohwer · San Diego State University · R21 · FY2011 · AI

Dietary restriction and associated changes in gut microbiota to prevent Alzheimer disease

$224,250
Kumar Sambamurti · Medical University Of South Carolina · R21 · FY2019 · AG

Microbial-ecology guided discovery of non-traditional therapeutics that limit resistance

$224,200
Jason Christopher Kwan · University Of Wisconsin-Madison · R21 · FY2016 · AI

Exploration, conservation, & development of marine biodiversity in Fiji and the S

$224,177
Mark E Hay · Georgia Institute Of Technology · U19 · FY2018 · TW

Laboratory & Biobehavioral Marker Core E

$224,151
Kelly L Jordan-Sciutto · University Of Pennsylvania · P30 · FY2023 · MH

Trace the flow of genes in the gut microbiome of obese and lean twin pairs

$224,139
Robin Knight · Washington University · P01 · FY2008 · DK

Surgical Research Training in Gastrointestinal Diseases

$224,126
Mark R Hellmich · University Of Texas Med Br Galveston · T32 · FY2020 · DK

TOPIC 22. SUBTOPIC A. PROJECT TITLEAN ANALYTICAL TECHNOLOGY PLATFORM TO IDENTIFY SYMBIOTIC INTERACTIONS BETWEEN PGPR AND ROOT MICROBIOME MEMBERS FROM BIOFUEL FEEDSTOCKS

$224,094
Powers & Zahr, Llc · · FY2018 · Department of Energy

Developing a Molecular Map of Atopic Dermatitis Across Ethnicity and Severity Subtypes.

$224,076
Emma Guttman · Icahn School Of Medicine At Mount Sinai · U01 · FY2024 · AI

Developing a Molecular Map of Atopic Dermatitis Across Ethnicity and Severity Subtypes.

$224,076
Emma Guttman · Icahn School Of Medicine At Mount Sinai · U01 · FY2025 · AI

Developing a Molecular Map of Atopic Dermatitis Across Ethnicity and Severity Subtypes.

$224,076
Emma Guttman · Icahn School Of Medicine At Mount Sinai · U01 · FY2023 · AI

Developing a Molecular Map of Atopic Dermatitis Across Ethnicity and Severity Subtypes.

$224,076
Emma Guttman · Icahn School Of Medicine At Mount Sinai · U01 · FY2020 · AI

Developing a Molecular Map of Atopic Dermatitis Across Ethnicity and Severity Subtypes.

$224,076
Emma Guttman · Icahn School Of Medicine At Mount Sinai · U01 · FY2022 · AI