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64,565 grants matching drug discovery

A redox-sensitive switch in the macrophage nucleus regulates acute phase inflammatory injury

$544,709
Marcelo G. Bonini · Northwestern University At Chicago · R01 · FY2024 · HL

Design of the First Mdm2 Targeting PROTACs for treatment of p53 Mutant or Deficient Cancers

$544,697
Joseph M Salvino · Wistar Institute · R01 · FY2025 · CA

DEVELOPMENTAL FUNDS (Core-002)

$544,647
Jennifer A Pietenpol · Vanderbilt University Medical Center · P30 · FY2017 · CA

DEVELOPMENTAL FUNDS (Core-002)

$544,647
Jennifer A Pietenpol · Vanderbilt University Medical Center · P30 · FY2018 · CA

AI-based platform for predicting emerging vaccine-escape variants and designing mutation-proof antibodies

$544,602
Guowei Wei · Michigan State University · R01 · FY2024 · AI

Discovery of functionally selective Alzheimer's disease therapeutics

$544,576
Robert R Luedtke · University Of North Texas Hlth Sci Ctr · R01 · FY2019 · AG

COBRE: LOUISVILLE RES FOUND INC: ALTERATION &RENOVATION

$544,567
University Of Louisville · P20 · FY2005 · RR

Development of novel antivirals for arthritogenic alphaviruses

$544,521
Donghoon Chung · University Of Louisville · R01 · FY2025 · AI

Hepatic Wnt/LRP6 Regulation of Plasma Lipids

$544,492
Arya Mani · Yale University · R01 · FY2015 · HL

Human ion channel pharmacology in droplet bilayer membranes

$544,482
Jason L. Poulos · Librede, Inc. · R44 · FY2014 · GM

3-Dimensional modeling of basal cell function in pseudostratified epithelia

$544,478
Sylvie Breton · Massachusetts General Hospital · R01 · FY2009 · DK

Maintenance of genome stability in 3D

$544,454
Jean Gautier · University Of Tx Md Anderson Can Ctr · R01 · FY2025 · CA

Gene Regulation in the Opioid Dependent Human Brain (Project 2)

$544,428
Peter Christopher Scacheri · Research Triangle Institute · P50 · FY2024 · DA

Tretment of negative symptoms and cognitive impairment in schizoprenia

$544,419
Robert W Buchanan · University Of Maryland Baltimore · P50 · FY2008 · MH

Chemoprevention of Early Pulmonary Lesions in Mice

$544,396
University Of Colorado Denver · R01 · FY2004 · CA

Novel peptide-coated suture for cleft lip and palate repair

$544,364
Zhong Zheng · Scarless Laboratories, Inc. · R44 · FY2017 · DE

Cancer Research Training in Molecular Biology

$544,335
Sarah J Parsons · University Of Virginia · T32 · FY2008 · CA

Structure-Guided Studied of GPCRs of RAS

$544,287
Sadashiva S. Karnik · Cleveland Clinic Lerner Com-Cwru · R01 · FY2019 · HL

Structure-Guided Studied of GPCRs of RAS

$544,287
Sadashiva S. Karnik · Cleveland Clinic Lerner Com-Cwru · R01 · FY2018 · HL

Contributions of prion strains and substrains to prion zoonotic potential and evolution

$544,279
Jason C Bartz · Creighton University · R01 · FY2025 · NS

Defining a pathway for mitochondrial heme trafficking

$544,180
Dennis J Stuehr · Cleveland Clinic Lerner Com-Cwru · R01 · FY2023 · GM

Redox Transduction of Nitric Oxide Signaling

$544,149
Bruce A Freeman · University Of Pittsburgh At Pittsburgh · R37 · FY2015 · HL

G Protein-Coupled Receptor Regulation in Airway Myocytes

$544,142
Raymond B. Penn · Thomas Jefferson University · R01 · FY2025 · HL

Targeting the PlsX/Y pathway for novel antimicrobials

$544,103
Richard Edward Lee · St. Jude Children'S Research Hospital · R01 · FY2009 · AI

Novel mechanisms of Alveolar Macrophage-Dependent Antifungal Innate Immunity

$544,080
Terry W Wright · University Of Rochester · R01 · FY2020 · AI