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17,054 grants matching genome editing

Role of the U-12 dependent Minor Spliceosome in Early Embryo Development and Brain Disease

$46,036
Taylor Floyd · Weill Medical Coll Of Cornell Univ · F31 · FY2021 · NS

Simultaneous Single-cell Lineage Tracing and Transcriptome Analysis for Mapping Human and Mouse Retinal Development

$46,036
Claire Bell · Johns Hopkins University · F31 · FY2021 · EY

Direct observation and quantification of the assembly of Cas9 ribonucleoprotein complex and its activity on nucleosomes at single molecule resolution

$46,036
Ikenna Okafor · Johns Hopkins University · F31 · FY2021 · GM

Determining the cell fate programs of mammalian retina development

$46,036
Martin Tran · California Institute Of Technology · F31 · FY2021 · EY

Determining the influence of 3D chromatin structure on human evolution

$46,036
Lana Harshman · University Of California, San Francisco · F31 · FY2021 · HG

Understanding OPA1 mutation-driven dominant optic atrophy using human PSC-derived retinal ganglion cells

$46,036
Katherine Anne Pohl · University Of California Los Angeles · F31 · FY2021 · EY

Defining the effects of noncoding genetic variation on human regulatory element activity

$46,036
Kari Strouse · Duke University · F31 · FY2021 · HG

Dissecting Gene Regulatory Roles of TET Enzymes and 5-hydroxymethylcytosine in Mammalian Active DNA Demethylation

$46,036
Alex Tianjiun Wei · University Of Pennsylvania · F31 · FY2021 · HG

Dynamics of Mitochondrial Inheritance in C. elegans Primordial Germ Cells

$46,036
Aaron Zachary Schwartz · New York University School Of Medicine · F31 · FY2021 · HD

Interrogating the role of mutant KRAS allelic imbalance and co-mutated genes in targeted therapy response of NSCLC

$46,036
Bianca Diaz · Weill Medical Coll Of Cornell Univ · F31 · FY2021 · CA

The conserved transcription factor UNC-30/PITX1-3 coordinates synaptogenesis and cell identity in C. elegans motor neurons

$46,036
Edgar Orlando Correa-Colã“n · University Of Chicago · F31 · FY2021 · NS

Defining mechanisms of lipoprotein turnover and their regulation by ASGR1

$46,036
Tabea Moll · Johns Hopkins University · F31 · FY2021 · HL

Harnessing the mesenchymal stromal cell secretome to target alpha-synuclein associated dysfunction in Parkinson's disease and related disorders.

$46,036
Jeremy Daniel Burgess · Mayo Clinic Jacksonville · F99 · FY2021 · AG

Progeria and Vasculature: Investigating Genetic Effects and the Potential of Genome Editing for Treatment

$46,036
Crystal Kennedy · Duke University · F31 · FY2021 · HL

Elucidation of mutant p53-medidated mechanisms in promoting metastatic esophageal cancer

$45,901
Gizem Efe · Columbia University Health Sciences · F31 · FY2022 · CA

Targeting the WNT Pathway in Colorectal Cancer

$45,891
Emma M Schatoff · Weill Medical Coll Of Cornell Univ · F31 · FY2018 · CA

Genome Editing Treatment for Catecholaminergic Polymorphic Ventricular Tachycardia

$45,877
Oliver Moore · Baylor College Of Medicine · F30 · FY2021 · HL

Functional Genomics

$45,834
Nevan J Krogan · University Of California, San Francisco · U54 · FY2019 · CA

Mechanisms of DNMT3B-mediated DNA Methylation Maintenance

$45,752
Bailey Michelle Tibben · Van Andel Research Institute · F31 · FY2022 · CA

In Vivo Gene Targeting to Treat Inherited Bone Disease

$45,700
David R Deyle · Mayo Clinic Rochester · R01 · FY2018 · AR

Mechanisms of TGFb in prostaglandin metabolism and fertilization

$45,587
Muhan Hu · University Of Alabama At Birmingham · F30 · FY2020 · HD

Neural and molecular control of subordinate social status in a cichlid fish

$45,566
Kathleen Munley · University Of California Los Angeles · F32 · FY2024 · GM

Base Editing Gene Correction of Pathogenic MYH7 Mutations in Models of Hypertrophic Cardiomyopathy

$45,559
Andreas C Chai · Ut Southwestern Medical Center · F30 · FY2023 · HL

The role of DNMT3A in gene regulation and stem cell expansion

$45,544
Yung-Hsin Huang · Baylor College Of Medicine · F99 · FY2017 · CA

Transcriptional Regulation of Cone Photoreceptor Genesis

$45,533
Mark M Emerson · City College Of New York · R01 · FY2022 · EY