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24,576 grants matching “microbiome”
Brain-Gut Microbiome-Visceral Adiposity Relationships in Multiethnic Adults
$237,470Unhee Lim · University Of Hawaii At Manoa · R21 · FY2015 · DK
Core F: Systems Biology & Biostatistics
$237,440Mark James Cameron · Case Western Reserve University · P30 · FY2025 · AI
Postdoctoral Training Program in Pulmonary and Critical Care Translational Research
$237,389Steven M Dudek · University Of Illinois At Chicago · T32 · FY2022 · HL
Biostatistics and Bioinformatics Core
$237,334Yu-Ping Wang · Tulane University Of Louisiana · U19 · FY2025 · AG
Tissue Acquisition And Cellular/Molecular Analysis Shared Resource (TACMASR)
$237,333Yana Zavros · University Of Arizona · P30 · FY2022 · CA
An engineered Clostridial consortia to interrogate immune modulation by secondary bile acids
$237,296Cathryn R Nagler · University Of Chicago · R21 · FY2024 · AI
Sequence-based Analysis of Parasite Diversity and Host Interactions
$237,278Ewen F Kirkness · J. Craig Venter Institute, Inc. · U19 · FY2014 · AI
Predoctoral Training Program in Immunology
$237,235Kevin L Legge · University Of Iowa · T32 · FY2022 · AI
PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRSV) CAUSES THE MOST COSTLY DISEASE TO SWINE PRODUCTION IN THE UNITEDSTATES. DISEASE CAUSED BY THIS VIRUS OFTEN INVOLVES SECONDARY BACTERIAL PATHOGENS, WHICH EXACERBATES RESPIRATORY DISEASE ANDINCREASES ANTIMICROBIAL ADMINISTRATION IN YOUNG GROWING PIGS. ALTHOUGH COMMERCIAL VACCINES ARE USED TO REDUCE THE EFFECTS OFPRRSV ON SWINE HEALTH, THE CURRENTLY AVAILABLE VACCINES ARE CONSIDERED INADEQUATE FOR DISEASE CONTROL. ALTERNATIVE STRATEGIESFOR CONTROL OF PRRSV IS NEEDED TO MAINTAIN SWINE HEALTH AND WELFARE WHILE LESSENING THE ECONOMIC EFFECTS OF THIS DISEASE ONPORK PRODUCERS. THE GOAL OF THIS WORK IS TO INVESTIGATE THE GUT MICROBIOME AS AN ALTERNATIVE TOOL FOR PRRSV CONTROL DUE TO ITSIMPACT ON THE IMMUNE SYSTEM AND OUTCOME AFTER INFECTION. OBJECTIVES OF THE WORK INCLUDE INVESTIGATING THE EFFECTS OFMICROBIOME MODULATION ON OUTCOME OF SWINE WITH RESPIRATORY DISEASE AND IDENTIFYING WHAT BENEFICIAL MICROBES ARE ASSOCIATEDWITH IMPROVED HEALTH. WE ANTICIPATE THE DATA GENERATED IN THIS PROJECT WILL ALLOW US TO CHARACTERIZE AND DETERMINE THE GUTMICROBES WHICH IMPROVE PIG HEALTH IN THE PRESENCE OF PRRSV. OUR GOAL IS TO DETERMINE HOW BENEFICIAL GUT MICROBES MAY BEUSED AS A PREVENTATIVE MEDICINE TOOL TO REDUCE THE EFFECTS OF RESPIRATORY DISEASE AND DECREASE THE NEED FOR ANTIMICROBIALS INSWINE. THE IMPACTS OF THIS WORK WILL IMPROVE ANIMAL WELFARE AND ANIMAL HEALTH, LESSEN THE ECONOMIC LOSSES TO PRODUCERSASSOCIATED WITH PRRSV, AND REDUCE THE RISK OF ANTIMICROBIAL RESISTANCE IN SWINE.
$237,204Regents Of The University Of Minnesota · · FY2024 · National Institute of Food and Agriculture
Tissue Acquisition And Cellular/Molecular Analysis Shared Resource (TACMASR)
$237,191Yana Zavros · University Of Arizona · P30 · FY2024 · CA
Tissue Acquisition And Cellular/Molecular Analysis Shared Resource (TACMASR)
$237,191Yana Zavros · University Of Arizona · P30 · FY2023 · CA
Core B: Data Management and Analysis Core (DMAC)
$237,186Fei Zou · Univ Of North Carolina Chapel Hill · P42 · FY2025 · ES
Core Support for Cancer Center
$237,147Edward Chu · Albert Einstein College Of Medicine · P30 · FY2021 · CA
Spatial characterization of microbial communities in the cystic fibrosis lung
$237,045Ryan Coulson Hunter · University Of Minnesota · R00 · FY2013 · HL
Genetic characterization of the murine type I Interferon locus
$237,033Christian W Schindler · Columbia University Health Sciences · R21 · FY2014 · AI
Mechanistic Analyses of the Genetic Variation of Preterm Birth Using the Collaborative Cross Mice
$237,009Elizabeth A Bonney · University Of Vermont & St Agric College · R21 · FY2021 · AI
Prostaglandins as protective mediators in Clostridium difficile infection
$237,000David M Aronoff · Vanderbilt University Medical Center · R21 · FY2016 · AI
Studies on the virulence of Fillifactor alocis
$237,000Hansel M. Fletcher · Loma Linda University · R21 · FY2012 · DE
Investigate the impact of physiological microbial exposure on regulatory T cell-mediated immune regulation
$237,000Li-Fan Lu · University Of California, San Diego · R21 · FY2023 · AI
Hypovitaminosis D promotes MED12-associated genomic instability in uterine fibroids
$236,985Thomas G Boyer · University Of Texas Hlth Science Center · R01 · FY2019 · HD
Human Papillomavirus (HPV) Natural History, Genomics and Risk Assessment
$236,936Mark Schiffman · Division Of Cancer Epidemiology And Genetics · ZIA · FY2021 · CA
Core Support for Cancer Center
$236,823Edward Chu · Albert Einstein College Of Medicine · P30 · FY2020 · CA
Fecal Bacteriotherapy for Relapsing Clostridium difficile Infection
$236,814Colleen Renee Kelly · Miriam Hospital · R21 · FY2012 · DK
Therapy with fecal microbiota transplantation and immune checkpoint blockade for solid tumors
$236,768Hassane M Zarour · University Of Pittsburgh At Pittsburgh · U01 · FY2022 · CA
The role of LSD1 in regulating periodontal induced bone loss
$236,756Kim Carpenter Mansky · University Of Minnesota · R21 · FY2025 · DE