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17,054 grants matching “genome editing”
Starter Grant: Cis-acting signals and genome-wide effects of extensive genome processing in diverse ciliates
$50,000Rebecca A Zufall · University Of Houston · · FY2006 · BIO
I-Corps: Targeted Epigenetic Modulation to Activate Therapeutic Genes
$50,000Isaac Hilton · William Marsh Rice University · · FY2023 · TIP
C9ORF72 in Motor System Biology and ALS
$50,000Kevin C Eggan · Harvard University · R01 · FY2016 · NS
**AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** IN SEPTEMBER 2022, THE GENOME-EDITED MICROBIAL WORKSHOP/CONFERENCE SERIES WAS FIRST HELD IN WASHINGTON, D.C. BY CERSA. SINCE THEN, IT HAS MET TWO MORE TIMES IN JUNE 2023 (IN-PERSON) AND NOVEMBER 2023 (VIRTUALLY). THE FIRST WORKSHOP DISCUSSED CHALLENGES AND CONCERNS RELEVANT TO GENOME-EDITED MICROBIAL REGULATION AND PROVIDE DIRECTION FOR STAKEHOLDERS IN THE REGULATORY SPACE.THE GOAL OF THE FIRST WORKSHOP WAS TO DISCUSS ISSUES AND CONCERNS RELATED TO GENOME-EDITED MICROBIAL REGULATION AND PROVIDE GUIDANCE FOR REGULATORY STAKEHOLDERS. DURING THIS MEETING, MEMBERS OF INDUSTRY, GOVERNMENT, AND ACADEMIC EXPERTS DISCUSSED CONCERNS RELATED TO THE REGULATION OF GENOME-EDITED MICROBIAL PRODUCTS. THE GROUP DEVELOPED A CONSENSUS STATEMENT TO REPRESENT THEIR COLLECTIVE VIEWPOINTS ON THE MATTER, WHICH WAS THEN SHARED WITHIN THEIR NETWORKS AND USED TO GUIDE FURTHER EXPLORATION IN THIS AREA.USING THE CONSENSUS STATEMENT AS A STARTING POINT, CERSA CREATED A FRAMEWORK FOR THE SECOND MEETING IN JUNE 2023. PARTICIPANTS DISCUSSED ONGOING CONCERNS IN GENOME-EDITED MICROBIAL REGULATION AND DEVELOPED AN OUTLINE OF THE TOPICS THAT WERE DISCUSSED DURING THE MEETING. THE GROUP ALSO DISCUSSED WAYS TO CREATE A MORE TRANSPARENT AND EFFICIENT REGULATORY BODY AND IDENTIFIED WHO ELSE NEEDED TO BE INCLUDED IN THE CONVERSATION TO ACHIEVE THIS. WE WILL BUILD ON THESE SUGGESTIONS WHEN WE DEVELOP OUR INVITEE LIST FOR THIS CONFERENCE.AFTER THE SECOND MEETING, SIX WORKING GROUPS WERE FORMED TO FOCUS ON QUESTIONS DISCUSSED DURING THE MEETING. THESE GROUPS MET VIRTUALLY IN NOVEMBER 2023 TO UPDATE THE LARGER GROUP ON THEIR PROGRESS. AT THAT TIME, AREAS OF FOCUS, RESEARCH TOPICS TO EXPLORE, AND NEXT STEPS CONCERNING REGULATORY MATTERS WERE IDENTIFIED. THE FULL VIDEO OF THIS MEETING IS AVAILABLE ONLINE AT CERSA'S WEBSITE. THIS CONFERENCE GRANT PROPOSAL IS REQUESTING FUNDS TO SUPPORT A 3RD IN-PERSON CONFERENCE TO FURTHER THE CONVERSATION THAT WAS STARTED IN SEPTEMBER 2022.IN OUR LAST GROUP MEETING IT WAS AGREED THAT THERE WERE A NUMBER OF GAPS IN OUR COLLECTIVE KNOWLEDGE THAT WOULD BE HELPFUL TO SEE ADDRESSED IN ADVANCE OF THE NEXT MEETING. AS SUCH, WE WILL COMPLETE A LITERATURE REVIEW TO BE SHARED WITH THE INVITEES AND PARTICIPANTS OF OUR NEXT CONFERENCE. ONCE THE LITERATURE REVIEW IS COMPLETE, WE WILL SHARE IT WITH THE PARTICIPANTS OF THE CONFERENCE WE ARE NOW PLANNING TO HOST.
$50,000North Carolina State University · · FY2024 · National Institute of Food and Agriculture
I-Corps: Silicon Nanoneedle Chip Technology for Massively Parallel Gene Editing
$50,000Rhonda Shrader · University Of California-Berkeley · · FY2017 · TIP
Molecular and anatomical basis of sleep regulation by SLEEPLESS
$50,000William J Joiner · University Of California, San Diego · R01 · FY2011 · NS
I Corps: Development of Genome Edited Cancer Vaccines
$50,000Kaiming Ye · Suny At Binghamton · · FY2019 · TIP
DNA Methylation and Hydroxymethylation During Retinal Development and Stem Cell Maintenance
$50,000Jeffrey Gross · University Of Pittsburgh At Pittsburgh · R01 · FY2018 · EY
I-Corps: Curing inherited diseases at the source through next-generation clustered regularly interspaced short palindromic repeat (CRISPR) systems
$50,000Jennifer A Doudna · University Of California-Berkeley · · FY2022 · TIP
Workshop Proposal: Advanced Crop Improvement: meeting challenges for food security, Senegal, October 27 - Nov 9, 2019
$49,996Jan E Leach · Colorado State University · · FY2019 · BIO
Leveraging CRISPR RNA-guided DNA Transposases for Gene Insertion at the CFTR Locus
$49,946Rebeca Teresa King · Columbia University Health Sciences · F31 · FY2024 · HL
Parametric design software for nanostructured CRISPR payloads
$49,930Steven L Armentrout · Parabon Nanolabs, Inc. · R43 · FY2024 · GM
Mechanisms and functions of N6-methyladenosine (m6A) in cancer
$49,919Samie R Jaffrey · Weill Medical Coll Of Cornell Univ · R01 · FY2020 · CA
Understanding Complex Genome Editing and RNA Biology in Oxytricha
$49,853Laura F Landweber · Columbia University Health Sciences · R35 · FY2024 · GM
High-throughput characterization of epigenetic context on DNA double strand break repair dynamics
$49,629Roger Zou · Johns Hopkins University · F30 · FY2022 · CA
Genetic analysis of type II diabetes
$49,571Francis Sellers Collins · National Human Genome Research Institute · ZIA · FY2024 · HG
Impact of mtDNA Mutations and Transfer on Tumor Growth Dynamics
$49,556Amy Katherine Yu · University Of California Los Angeles · F30 · FY2022 · CA
Therapeutic Editing of Rod Glycolysis Rescues Retinal Degeneration
$49,538Nicholas David Nolan · Columbia University Health Sciences · F31 · FY2025 · EY
Interrogation of Non-Canonical Roles of VGSCs in Neurodevelopmental Epilepsy
$49,538Kyle Helms · Columbia University Health Sciences · F31 · FY2025 · NS
Structural and evolutionary basis for insertion unidirectionality in RNA-guided DNA transposition systems
$49,538Vinh H Truong · St. Jude Children'S Research Hospital Graduate School Of Biomedical Sciences, Llc · F31 · FY2025 · GM
Understanding Kras Mutation Heterogeneity in PDAC
$49,538Whitney Juliet Sisso · Weill Medical Coll Of Cornell Univ · F31 · FY2025 · CA
Investigating the role of protein quality control in osmotic stress adaptation
$49,538Kathy H Le · Stanford University · F31 · FY2025 · GM
Determining the role of nuclear envelope reformation proteins in regulating the cGAS/STING innate immune response in cancer
$49,538Anthony Wayne Isenhour · Yale University · F31 · FY2025 · CA
Investigating the roles of METTL3 and M6A modification in colorectal cancer progression
$49,538Hung Mai · Washington University · F31 · FY2025 · CA
Mechanisms of gene regulation by an E3 ubiquitin ligase during neurodevelopment
$49,538Nicole A. Hall · New York University School Of Medicine · F31 · FY2025 · NS