Sort
38,696 grants matching “als”
Mediators and Moderators of Exercise Behavior Change
$358,023Angela D Bryan · University Of Colorado · R01 · FY2006 · CA
Electric Field as Novel Neuronal Interface
$358,015George Mason University · R01 · FY2005 · EB
tRNA-derived stress-induced RNAs and translational control
$358,000Pavel Ivanov · Brigham And Women'S Hospital · R01 · FY2024 · GM
tRNA-derived stress-induced RNAs and translational control
$358,000Pavel Ivanov · Brigham And Women'S Hospital · R01 · FY2025 · GM
tRNA-derived stress-induced RNAs and translational control
$358,000Pavel Ivanov · Brigham And Women'S Hospital · R01 · FY2023 · GM
tRNA-derived stress-induced RNAs and translational control
$358,000Pavel Ivanov · Brigham And Women'S Hospital · R01 · FY2022 · GM
SCIENTIFIC OBJECTIVES: OSIRIS-REX CAN BE THOUGHT OF AS A THERMAL EXPERIMENT. THE SAMPLES RETURNED FROM ASTEROID BENNU WILL PRESERVE A UNIQUE INVENTORY OF SOLAR SYSTEM VOLATILE BUILDING BLOCKS CONTROLLED BY THE TEMPERATURE HISTORY OF ITS SURFACE AND INTERIOR. THERMAL REMOTE SENSING OF ITS SURFACE WILL CONSTRAIN COMPOSITION AND PHYSICAL MATURITY OF THE SURFACE AND MATERIALS WE WILL RETURN. TEMPERATURES CONTROL BENNU'S ORBITAL EVOLUTION. THE PRIMARY OBJECTIVE OF THIS OSIRIS-REX PARTICIPATING SCIENTIST PROJECT IS TO ADVANCE THE SCIENTIFIC ANALYSIS OF BENNU WITH THERMAL MODELING. USING 3D THERMAL MODELING TOOLS AND EXPERIENCE WITH THERMAL INFRARED IMAGERY AND LASER REFLECTANCE DATA FROM THE MOON MERCURY AND ITOKAWA WE WILL INVESTIGATE AND AID CURRENTLY PLANNED INVESTIGATIONS BY ADDRESSING: 1) STABILITY OF SURFACE AND INTERIOR VOLATILES INCLUDING POSSIBLE VOLATILE OUTGASSING 2) SURFACE AND SUBSURFACE THERMAL PROPERTIES INCLUDING SURFACE ROCK SIZE AND FRACTION AND SAMPLE SITE SELECTION AND 3) YARKOVSKY AND YORP ACCELERATIONS. THIS MODEL HAS HERITAGE IN THE LRO DIVINER LUNAR THERMAL MODEL (PAIGE ET AL. 2010; SIEGLER ET AL. 2014 2016) AND MESSENGER THERMAL MODEL (PAIGE ET AL. 2013). ON MERCURY AND THE MOON THIS MODEL HAS BEEN USED TO ANALYZE THERMAL PROPERTIES OF THE LUNAR SUBSURFACE AND VOLATILE STABILITY IN SHADOWED REGIONS NEAR THE POLES. IT HAS ALSO BEEN DEMONSTRATED FOR SMALLER 3D OBJECTS SUCH AS ASTEROID ITOKAWA AND HAS BEEN APPLIED TO EXAMINING THE YARKOVSKY EFFECT DUE TO ASYMMETRIC HEATING ON AIRLESS BODIES (ADLER ET AL. 2013 LPSC). WE WILL WORK WITH EXISTING TEAM THERMAL MODELS (CHOI ET AL. 2014) TO CREATE A UNIFIED MODEL FRAMEWORK. WE SEE THIS MODEL AS AN IDEAL SUPPORTING APPLICATION FOR THE OSIRIS-REX INSTRUMENT PACKAGE IN SEVERAL KEY WAYS: IT WILL UTILIZE SHAPE MODEL DATA FROM OLA AND OCAMS TO PRODUCE A GLOBAL THERMAL MAP OF SURFACE AND SUBSURFACE TEMPERATURES. THIS WILL ALLOW FOR MAPPING OF EXPECTED SURFACE THERMAL INERTIA AND IDENTIFICATION OF REGIONS OF POSSIBLE VOLATILE STABILITY. WE WILL WORK WITH OTES TO PROVIDE AREAS WHERE ANOMALOUS THERMAL PROPERTIES HAVE BEEN DETECTED. OTES WILL PROVIDE SURFACE TEMPERATURES BUT THE MODEL WILL ALLOW FOR A FULL THERMAL HISTORY LINKING SEPARATE MEASUREMENTS IN TIME. IT CAN ACT AS A BASELINE THERMAL CORRECTION FOR OVIRS OBSERVATIONS IF COINCIDENT OTES MEASUREMENTS ARE UNAVAILABLE. WE WILL WORK WITH TEAM MEMBERS STUDYING THE YARKOVSKY EFFECT AND HOW THEIR STUDIES MIGHT UTILIZE OUR MODEL RESULTS.
$357,998Planetary Science Institute · · FY2020 · National Aeronautics and Space Administration
CBT for Adherence and Depression in Diabetes
$357,996Steven A Safren · Massachusetts General Hospital · R01 · FY2008 · MH
CBT for Adherence and Depression in Diabetes
$357,996Steven A Safren · Massachusetts General Hospital · R01 · FY2007 · MH
Characterization of mammalian COG complex-interacting intra-Golgi trafficking mac
$357,980Vladimir V Lupashin · Univ Of Arkansas For Med Scis · R01 · FY2012 · GM
Towards an Improved Understanding of BOLD Signal Changes
$357,960R. Todd Constable · Yale University · R01 · FY2010 · NS
Telepsychiatry & Culturally Sensitive Treatment of Depressed Asian Americans
$357,919Albert S. Yeung · Massachusetts General Hospital · R01 · FY2009 · MH
Emergence of Grammar in a New Sign Language
$357,917Carol Padden · University Of California, San Diego · R01 · FY2010 · DC
Anti-repression Mechanisms in p53-Mediated Stress Responses
$357,857Wei Gu · Icahn School Of Medicine At Mount Sinai · P01 · FY2011 · CA
Mechanisms of Brain Tumor Stem Cell Growth and Differentiation
$357,857John Park · National Institute Of Neurological Disorders And Stroke · ZIA · FY2012 · NS
Role of autophagy in normal and transformed hematopoietic stem cells
$357,814Emmanuelle Passegue · University Of California, San Francisco · R01 · FY2016 · CA
Model for SorCS1-mediated Diabetes with Dementia
$357,804Samuel E Gandy · Icahn School Of Medicine At Mount Sinai · R01 · FY2013 · NS
RapidâResponse Macromolecular Crystallography
$357,772Corie Y Ralston · University Of Calif-Lawrenc Berkeley Lab · P30 · FY2017 · GM
C-reactive protein promotes myeloma cell-mediated bone destruction
$357,767Qing Yi · University Of Tx Md Anderson Can Ctr · R01 · FY2012 · CA
C-reactive protein promotes myeloma cell-mediated bone destruction
$357,767Qing Yi · University Of Tx Md Anderson Can Ctr · R01 · FY2011 · CA
ROLES FOR ALPHA-SYNUCLEIN DEGRADATION AND CYTOSOLIC DOPAMINE IN PD PATHOGENESIS
$357,760David Sulzer · Columbia University Health Sciences · P50 · FY2009 · NS
Improving Medication Continuity among Adolescents with ADHD
$357,750William Bernard Brinkman · Cincinnati Childrens Hosp Med Ctr · R34 · FY2018 · MH
Use of Exercise to Reduce Young Adult Marijuana Use There is an App for That
$357,750R. Lorraine Collins · State University Of New York At Buffalo · R34 · FY2014 · DA
Use of Exercise to Reduce Young Adult Marijuana Use There is an App for That
$357,750R. Lorraine Collins · State University Of New York At Buffalo · R34 · FY2013 · DA
ADENOSINE A1 AND A2 RECEPTORS IN THE MYOCARDIUM
$357,750Univ Of Massachusetts Med Sch Worcester · R01 · FY2003 · HL