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91,797 grants matching “obesity”
Integrated Demographic and Health Survey Data for Population Health Research
$650,284Elizabeth H Boyle · University Of Minnesota · R01 · FY2023 · HD
Neuroscience-based Interventions for Cancer Risk Behavior Change
$650,280Caryn Lerman · University Of Pennsylvania · R35 · FY2018 · CA
Translational Diebetes Prevention in GDM
$650,243Assiamira Ferrara · Kaiser Foundation Research Institute · R18 · FY2012 · DK
Enhancing Assisted Reproductive Technologies with Deep Learning and Data Visualization
$650,231Hanspeter Pfister · Harvard University · R01 · FY2024 · HD
Small molecules targeting hepatic glucose production and insulin resistance
$650,222Pere Puigserver · Dana-Farber Cancer Inst · R01 · FY2023 · DK
Metabolomics from a Controlled Feeding Study and Large Cohorts to Identify Diet-Associated Biomarkers, Augmented by Genetics to Infer Causality for Cardiometabolic Outcomes
$650,217Joel N Hirschhorn · Boston Children'S Hospital · R01 · FY2023 · DK
Metabolomics from a Controlled Feeding Study and Large Cohorts to Identify Diet-Associated Biomarkers, Augmented by Genetics to Infer Causality for Cardiometabolic Outcomes
$650,217Joel N Hirschhorn · Boston Children'S Hospital · R01 · FY2022 · DK
Metabolic Control Analysis
$650,211Richard L Veech · National Institute On Alcohol Abuse And Alcoholism · ZIA · FY2011 · AA
Epidemiology of CHD of Men Aged 40+
$650,148University Of Pittsburgh At Pittsburgh · R01 · FY2005 · HL
Sleep Apnea Endophenotypes: One Size Does Not Fit All
$650,142Atul Malhotra · University Of California, San Diego · R01 · FY2024 · HL
Lifecourse Exposures & Diet: Epigenetics, Maturation & Metabolic Syndrome
$650,136Karen Eileen Peterson · University Of Michigan At Ann Arbor · P01 · FY2014 · ES
Uncoupling obesity from breast cancer in African American women
$650,118Gerald V Denis · Boston University Medical Campus · U01 · FY2017 · CA
Optimizing Individualized and Adaptive mHealth Interventions via Control Systems Engineering Methods
$650,111Eric Hekler · University Of California, San Diego · R01 · FY2020 · CA
Counseling for Overweight Women for Diet and Activity
$650,097San Diego State University · R01 · FY2002 · CA
Impact of Early Life Experience on Vagal Neurons and Circuits
$650,093Pat R Levitt · Children'S Hospital Of Los Angeles · R01 · FY2024 · DK
Multiethnic Fine-Mapping of Polycystic Ovary Syndrome Susceptibility Loci
$650,056Andrea Dunaif · Northwestern University At Chicago · R01 · FY2016 · HD
Peer-Based Approaches to Enhance Physical Activity in Dyads of Inactive Women
$650,051Larkin Strong · University Of Tx Md Anderson Can Ctr · R01 · FY2025 · HL
Role of Pharmacotherapy in Counteracting Weight Regain in Adolescents with Severe Obesity
$650,033Aaron S Kelly · University Of Minnesota · R01 · FY2021 · DK
Sex-dependent regulation of cardiac cAMP, ECC, and arrhythmia by phosphodiesterases
$650,028Yang K Xiang · University Of California Los Angeles · R01 · FY2025 · HL
Lactation and Incidence of Diabetes Mellitus in CARDIA Women
$650,027Erica P Gunderson · Kaiser Foundation Research Institute · R01 · FY2012 · DK
Antihypertensive Mechanisms of Minocycline in Resistant Hypertension: Role of the gut microbiota-brain-immune axis
$650,022Steven Michael Smith · University Of Florida · R01 · FY2025 · HL
Using Metabolomics to Define the Behavioral Phenomics of Energy Balance and Exercise Response
$650,017Molly Bray · University Of Texas At Austin · R01 · FY2021 · DK
The Johnston County OA Project: Arthritis and Disability
$650,000Joanne M. Jordan · Univ Of North Carolina Chapel Hill · U01 · FY2014 · DP
Cardiovascular Disease in Pima Indians
$650,000Barbara V Howard · Medstar Health Research Institute · U01 · FY2011 · HL
** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** FLAVONOIDS ARE COMPOUNDS PLANTS PRODUCE TO PROTECT THEMSELVES AGAINST VARIOUS STRESSES THAT ARE EXPECTED TO BECOME MORE PROMINENT AS THE RESULT OF CLIMATE CHANGE. THIS INCLUDES ATTACK BY PATHOGENIC MICROBES, TEMPERATURE EXTREMES, AND UV RADIATION. SEVERAL FLAVONOIDS ARE ALSO OF INTEREST AS ANTI-CANCER DRUGS OR AS NUTRACEUTICALS - COMPOUNDS IN OUR FOOD THAT HAVE POSITIVE EFFECTS ON HEALTH, FOR EXAMPLE BY SLOWING DOWN THE EFFECTS OF AGING OR REDUCING THE RISK OF OBESITY. OF SPECIAL INTEREST WITH RESPECT TO THE LATTER TWO APPLICATIONS ARE 3-DEOXYANTHOCYANIDINS (3-DOA), WHICH THE CERAL CROP SORGHUM, BUT NOT THE OTHER CEREALS (E.G. MAIZE, WHEAT), CAN SYNTHESIZE, BUT WHOSE BIOSYNTHESIS IS NOT YET FULLY UNDERSTOOD. WE PROPOSE A DETAILED ANALYSIS OF HOW SORGHUM PLANTS PRODUCE FLAVONOIDS, AS THE BASIS FOR THE TAILORED PRODUCTION OF BIO-ACTIVE COMPOUNDS, I.E. PLANTS THAT PRODUCE SPECIFIC FLAVONOIDS, AND IN GREATER QUANTITY. THIS APPROACH RELIES ON A DETAILED ANALYSIS OF THE ENZYMES INVOLVED IN FLAVONOID BIOSYNTHESIS TO FIGURE OUT THEIR EXACT MODE OF ACTION. AS A NEXT STEP, THEIR PROPERTIES CAN BE MODIFIED.
$650,000University Of Florida · · FY2023 · National Institute of Food and Agriculture