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17,828 grants matching crispr

Leveraging cancer-specific defects in nuclear integrity to inform novel synthetic lethal strategies

$182,156
Charles Patrick Lusk · Yale University · R21 · FY2020 · CA

A modular, customizable sequencing system for simultaneous genotyping and transcript analysis in single cells

$182,156
Manuel Garber · Univ Of Massachusetts Med Sch Worcester · R21 · FY2021 · CA

A modular, customizable sequencing system for simultaneous genotyping and transcript analysis in single cells

$182,156
Manuel Garber · Univ Of Massachusetts Med Sch Worcester · R21 · FY2020 · CA

Genome Engineering Core

$182,011
Farshid Guilak · Washington University · P30 · FY2022 · AR

Dissecting the sensory hair cell nucleus: Development of a novel method for investigating chromatin interactions (Tn5-Capture) in small cell numbers

$181,875
Litao Tao · Creighton University · R21 · FY2024 · DC

Dissecting the sensory hair cell nucleus: Development of a novel method for investigating chromatin interactions (Tn5-Capture) in small cell numbers

$181,875
Litao Tao · Creighton University · R21 · FY2023 · DC

Chemically ligated-guide RNA (lgRNA)-based CRISPR/Cas9 gene editing for elimination of hepatitis B virus cccDNA

$181,875
Ju-Tao Guo · Baruch S. Blumberg Institute · R21 · FY2025 · AI

Correction of endocrine disruptor-induced transgenerational epimutations by CRISPR-dCas9

$181,875
Ramji Kumar Bhandari · University Of North Carolina Greensboro · R21 · FY2021 · HD

A Molecular Grammar for Guide RNAs (gRNAs) with Engineered Secondary Structures

$181,875
Eric Alan Josephs · University Of North Carolina Greensboro · R21 · FY2022 · EB

Murine Mutagenesis Core

$181,823
Xinzhong Dong · Johns Hopkins University · P30 · FY2019 · NS

A new bladder cancer model based on tissue reprogramming and gene targeting

$181,790
Flaminia Talos · State University New York Stony Brook · R21 · FY2021 · CA

Murine Mutagenesis Core

$181,777
Xinzhong Dong · Johns Hopkins University · P30 · FY2018 · NS

Next generation of delivery platform for Prime editors based on an RNA vector for Sickle cell disease: the “all-in-one” vector

$181,575
Patricia Devaux · Mayo Clinic Rochester · R21 · FY2025 · EB

Tumor Intrinsic Regulation of Immune Evasion Pathways in Breast Cancer

$181,475
Sheera Rosenbaum · University Of Colorado Denver · K00 · FY2024 · CA

Murine Mutagenesis Core

$181,453
Xinzhong Dong · Johns Hopkins University · P30 · FY2017 · NS

De novo development of small CRISPR-Cas proteins using artificial intelligence algorithms

$181,436
Jin Liu · University Of North Texas Hlth Sci Ctr · R21 · FY2023 · GM

Chemical- and Photo-Inducible CRISPR-Guided Epigenome Editing

$181,192
Fu-Sen Liang · University Of New Mexico · R21 · FY2016 · HG

Core D: CRISPRi/a Core

$181,010
Martin Kampmann · Weill Medical Coll Of Cornell Univ · U54 · FY2019 · NS

Murine Mutagenesis Core

$180,990
Xinzhong Dong · Johns Hopkins University · P30 · FY2016 · NS

Identification of Novel Regulators of Natural Killer Cell Activity

$180,970
Dan S Kaufman · University Of California, San Diego · R21 · FY2022 · CA

Development of a microfluidic primary cell editing platform (pCEP) for personal gene therapy

$180,836
Soojung Claire Hur · Johns Hopkins University · R21 · FY2022 · CA

Halting Breast Cancer Metastasis by Blocking Cancer-MSC Engulfment

$180,632
Yu-Chih Chen · University Of Pittsburgh At Pittsburgh · R21 · FY2025 · CA

From synapse to function: cocaine-induced cell-type- and circuit-specific accumbal proteome changes

$180,606
Yun Young Yim · Icahn School Of Medicine At Mount Sinai · K01 · FY2025 · DA

CANcer Cachexia Action Network/CANCAN

$180,544
Mariam Jamal-Hanjani · University College London · OT2 · FY2023 · CA

Toward a Curative Treatment for HBV with cccDNA-Targeting Peptide Nucleic Acids

$180,537
Keith Thomas Gagnon · Wake Forest University Health Sciences · R21 · FY2024 · AI